By Irem OnurUrocortin: A biomarker deserving investigation for endometriosis patients
By Irem Onur
Urocortin is a neuropeptide in the corticotropin-releasing hormone family and is expressed by eutopic and ectopic human endometria. Since it has paracrine and immunomodulatory effects, urocortin is thought to contribute to the pathogenesis of endometriosis. Its expression has been thoroughly…
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By Hale Goksever CelikThe coexistence deep infiltrating endometriosis and fibromyalgia
By Hale Goksever Celik
Endometriosis is defined as the localization of endometrial glandular and stromal cells outside the uterine cavity. The main symptoms of endometriosis which are dysmenorrhea, dyspareunia, and chronic pelvic pain impair the quality of life of these women. This disease may…
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By Selma OransayAntimullerian Hormone, endometrioma and ovarian reserve
By Selma Oransay
Younis et al. from Baruch-Padeh Medical Center, Poriya, Israel, designed a review study on ovarian reserve alterations before and after endometrioma surgery that recently documented in "Human Reproduction Update". The authors examined the electronic databases of articles published between January…
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By Engin AydinA highly sensitive Immunohistochemical Marker for Stromal Cells in endometriosis
By Engin Aydin
Endometriosis is diagnosed histopathologically by the presence of endometrium-like tissues outside the uterus. Positive CD10 immunohistochemistry, highlighting stromal cells of the endometrium, is a useful adjunct for pathologists in the tissue diagnosis. However, CD10 expression is not specific to endometrial stromal…
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The appearance of postoperative endometriosis by imaging methods
By Hale Goksever Celik
Endometriosis is a chronic gynecological disease mostly encountered in reproductive-aged women. Endometriosis can occur in three different entities: peritoneal, ovarian and deep endometriosis. Golden standard diagnosis is made by histopathological examination of surgical material after laparoscopic surgery in women with…
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The miscarriage rate in women with endometriosis undergoing IVF fresh cycles
By Hale Goksever Celik
Endometriosis is a chronic estrogen-dependent disease diagnosed in 25-40% of women with infertility. There are several mechanisms explaining the negative impacts of endometriosis on fertility through the entire reproductive process such as sperm-oocyte interaction, ovarian reserve, and implantation. Endometriosis is…
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By Dr. Youngran ParkEndometrioma, Fertility, and Assisted Reproduction
By Dr. Youngran Park
Endometriosis can negatively impact a woman’s health and quality of life. Surgery has been considered the primary treatment to overcome infertility in cases of ovarian endometrioma. Patients struggling with endometriosis often pursue assisted reproductive technologies (ART) due to fertility issues.…
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By Özge ÖzkayaFurther Results From the FEELING Study Published
By Özge Özkaya
Some women are more likely to develop deep infiltrating endometriosis according to the further analysis of the results of the FEELING study. These are women who: are married, are older, have siblings, have had a prior pregnancy, or for whom…
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Does ovarian endometrioma damage the ovarian reserve?
By Dr. Youngran Park
Ovarian endometriomas are commonly present in 17% to 44% of women with endometriosis and are often associated with infertility and pelvic pain. There are several treatment options including surgical treatment. Cyst excision is associated with better results in terms of…
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The diagnosis and management of endometriosis in Korea
By Selma Oransay
The Korean Society of Endometriosis has scrutinized the present published literature of endometriosis in the domestic and international platform to provide new guidelines and the clinical management of the disease. The study was recently published in the journal "Obstetrics and Gynecology…
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By Murat OsmanHow Ovarian Endometriomas and DIE affect ART outcomes
By Murat Osman
Previous studies have evaluated the impact of an ovarian endometrioma on ovarian reserve and its impact on the success of assisted reproductive technology (ART) outcomes have controversial results. ART is a method by which a woman’s own hormones are used…
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Endometrioma and endometriosis
By Irem Onur
Exacoustos C. et al. published an article titled “The isolated ovarian endometrioma: a history between myth and reality” in the Journal of Minimally Invasive Gynecology in 2018. They aimed to examine the association between ovarian endometriomas detectable at the transvaginal ultrasound…
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Personalised Medicine for Endometriosis?
By Özge Özkaya
The lining of the uterus of women with endometriosis is different from that of women without the disease even if they have chronic pelvic pain found a study published in the scientific journal Biology of Reproduction. The difference is found…
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Is there a definitive guideline for the surgical management of endometriosis?
By Murat Osman
Endometriosis is a chronic inflammatory disease that is defined by the presence of ectopic endometrial tissue outside of the uterus. Unfortunately, endometriosis continues to be a leading cause of chronic pelvic pain in women of reproductive age. This article titled,…
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By Kasthuri NairNo Link Found Between Vitamin D and Endometriosis
By Kasthuri Nair
Buggio et al., a group of scientists from the Ospedale Maggiore Policlinico, Universita` degli Studi in Milan, recently published a paper in the Reproductive Sciences titled “25-Hydroxyvitamin D Serum Levels and Endometriosis: Results of a Case-Control Study.” The publication sought…
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An Unusual Case "Free Floating Omental Endometrioma"
By Kasthuri Nair
Capaccione et al. published an article in Radiology Case Reports titled “Massive endometrioma presenting with dyspnea and abdominal symptoms.” This publication is centered around a particularly unique case report of a woman who was ultimately diagnosed with endometriosis. The patient…
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A How-To Guide for Endometriosis Surgery
By Kasthuri Nair
The European Society for Gynaecological Endoscopy (ESGE), ESHRE, and the World Endometriosis Society (WES) recently published a document titled “Recommendations for the surgical treatment of endometriosis—part 1: ovarian endometriomas.” This publication provides surgeons with recommendations for the technical aspects of…
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Which Endometriosis Treatment is Better: NETA or Extended-cycle OC (Seasonique®)?
By Kasthuri Nair
Scala et al. recently shared the findings of their patient preference prospective study in a journal article titled “Norethindrone acetate versus extended-cycle oral contraceptive (Seasonique®) in the treatment of endometriosis symptoms: A prospective open-label comparative study,” which was published in the…
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Long-term Use of Dienogest can Prevent Recurrence of Endometriomas
By Kasthuri Nair
Chandra et al. recently published a paper titled “Clinical experience of the long-term use of dienogest after surgery for ovarian endometriomas” in Obstetrics and Gynecology Science. The publication explored the benefits and repercussions associated with long-term use of dienogest, a…
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Can Ovarian Stimulation Increase Endometrioma Volume?
By Kasthuri Nair
Seyhan et al. recently published a paper titled “Do endometriomas grow during ovarian stimulation for assisted reproduction? A three-dimensional volume analysis before and after ovarian stimulation” in Reproductive BioMedicine Online. The authors initially believe that ovarian stimulation, often used in…
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Ovarian Reserve Depletion is not Time Sensitive
By Kasthuri Nair
The European Journal of Obstetrics & Gynecology and Reproductive Biology recently published a paper titled “Is endometrioma-associated damage to ovarian reserve progressive? Insights from IVF cycles.” This publication by Benaglia et al. examines the controversial relationship between endometriosis and ovarian…
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Updates in the Field of Endometriosis: Imaging
By Kasthuri Nair
Hoyos, Johnson, and Puscheck wrote a chapter titled “Endometriosis and Imaging” that discusses the imagining technologies that can be used to diagnosis and examine individuals with the disease. This chapter evaluates three types of imagining, namely Ultrasound (US), Magnetic Resonance…
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Updates in the Field of Endometriosis: Fertility Preservation
By Kasthuri Nair
“Endometriosis and Fertility” is a chapter dedicated to examining the role of endometriosis and endometriomas in decreasing fertility. In other words, the authors of this chapter discuss the relationship between endometriomas, surgeries, and infertility. Barnett, Banks and Decherney also deliberate…
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By Yu YuOvarian Endometriomas vs Deep Infiltrating Endometriosis
By Yu Yu
Ovarian endometrioma (OMA) and deep infiltrating endometriosis (DIE) have been described as two disease entities, although they are both characterized by endometrial tissue located outside the uterus. As OMA and DIE look different histologically, it is puzzling what cause their…
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Reduced vascularization in ovarian endometriomas associated with less pain
By Yu Yu
Angiogenesis, i.e., the development of new blood vessels is believed to play an important role in endometriosis pathogenesis and symptoms. Endometriosis is associated and requires neovascularization to proliferate, invade surrounding normal structure in order to establish an endometriotic lesion. Ovarian…
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Hormonal Contraceptives and Endometriomas
By Kasthuri Nair
Hormonal contraceptive has recently become a popular choice of birth control for many women. The European Journal of Obstetrics & Gynecology and Reproductive Biology recently published an article entitled “Incidence of ovarian endometrioma among women with peritoneal endometriosis with and…
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ICSI Outcomes for Laparoscopic Intervention of Endometriosis
By Kasthuri Nair
Women with endometriosis can have trouble conceiving and often turn to fertility treatments for help. Guler et al. recently published a paper in Systems Biology in Reproductive Medicine titled “The Impact of laparoscopic surgery of peritoneal endometriosis and endometrioma on…
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Characteristics of Ovarian Endometriotic Cysts Could Help Determine Whether Endometrioma Will Reoccur
By Özge Özkaya
The features of ovarian endometriotic cysts could help predict whether endometrioma will re-occur in individual patients, according to a study published in the European Journal of Obstetrics and Gynecology. Predicting the risk of recurrence is important because it can help…
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