Bahar Yuksel, MD

Bahar Yuksel graduated from Istanbul University Istanbul Medical School at the top of the class of 2010. She completed her residency in Istanbul Medical School Obstetrics and Gynecology Department by the top score Residency Board Exam. Between 2016 and 2017 she studied at Stanford School of Medicine and did research about ovarian physiology.  Her projects were funded by The Scientific And Technological Research Council Of Turkey several times. Her main interests are endometriosis and ovarian physiology. Now she has her practice in Istanbul as an Ob&Gyn , member of Turkish Endometriosis and Adenomyosis Society and works for Endofoundation of America as Research Associate.

Does hysterectomy bring a total relief in patients with endometriosis?

There is a common belief that hysterectomy is the last option to relieve the pain in patients with endometriosis by stopping the production of menstrual material. The study entitled "Impact of hysterectomy on analgesic, psychoactive and neuroactive drug use in women with endometriosis, national cohort study" conducted in Sweden using a nation-wide surgery and drug use follow up system claimed it otherwise. The authors led by Dr.Brunes collected the data of patients who had a hysterectomy for benign diseases and selected…

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Endometrial fluid analysis as a new diagnostic test for endometriosis diagnosis

There is still a huge demand for finding a minimally invasive diagnostic test for endometriosis and yet none has been defined properly. The present study which was conducted in Cleveland Clinic by Natalia C. Llarena et al between March 2017 and October 2018 searched for the answer to this ever-going question and analyzed the cytokine profile for endometrial aspirates. The authors analyzed 60 patients including healthy controls and endometriosis patients while excluding any patients who have reasons for the potentially…

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Can a grape ingredient, resveratrol, be the promised warrior to defeat endometriosis?

Endometriosis is a chronic estrogen-dependent disorder and has a known relationship with angiogenesis, inflammation, and oxidative stress. Resveratrol is a part of a "polyphenol" compound which are thought to act like antioxidants, protects the body against damage. This compound is normally found in the skin of red grapes, but you can also find it in peanuts and berries. In a recent study conducted by Khazei et al. a phytoestrogen called Resveratrol which has anti-inflammatory, anti-estrogenic, anti-angiogenic, and antioxidant effects has been…

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Fallopian tube endometriosis

Endometriosis affects various tissues including pelvic and extra-pelvic organs. Fallopian tube endometriosis is not a widely studied topic in endometriosis, hence the real incidence is unknown as not all studies evaluate microscopically diagnosed Fallopian tube endometriosis. In the retrospective database study conducted by McGuinness and Farr Nezhad et al, the investigators sought to find the answers for the real incidence of tubal endometriosis. They analyzed the operative data of patients who underwent surgery for suspected endometriosis, and also evaluated the results…

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The more than expected prevalence of endometriosis in patients with Mullerian abnormalities

Congenital müllerian anomalies resulting in a spectrum of uterine abnormalities are caused by the abnormal embryologic fusion of the müllerian ducts to form a normal uterine cavity.  They are often unrecognized because they are usually asymptomatic. The presence of a uterine anomaly increases the risk of pregnancy loss and adverse pregnancy outcomes. The classification of uterine anomalies by American Fertility Society classification includes hypoplasia/agenesis, unicornuate, didelphys, bicornuate, septate, arcuate, and diethylstilbestrol-related. The prevalence of uterine malformations is up to 38 percent…

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Mental stress promotes mice endometriosis

Endometriosis is a disease for which pathogenesis and progression are not fully understood. Inflammation is one of the key candidates that might be related to the creation or progression of endometriosis. In the study conducted by Kawakita et al from Japan, the relation of mental stress on endometriosis distribution and the inflammatory reaction was examined. The authors created a mouse model and exposed one group to mental stress, and checked the presence of stress by daily controlled serum cortisol levels.…

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Reproductive capacity and recurrence rate after surgery for Stage III/IV endometriosis 

If gaining fertility back is the main goal, the surgical removal of endometriosis lesions is globally recognized as first-line therapy. Even though, pre- and postoperative hormone therapy leads to a significant decrease in the spread of the disease measured with the revised ASRM scores it is not an option for fertility preservation. In the study conducted in Hannover Medical School, the authors aimed to establish postoperative recurrence and pregnancy rates in patients after surgical resection of moderate and severe endometriosis lesions (rASRM stage…

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