Demet Candaş Green

Demet is an editorial coordinator at the University of California, Davis (UC Davis) responsible for editing and reviewing scientific elements of grant proposals. She holds a BS and an MS degree in Molecular Biology and Genetics from Boğaziçi University, Turkey; and a PhD in Biochemistry and Molecular Biology from UC Davis. She trained as a post-doctoral scholar at the UC Davis Comprehensive Cancer Center before she launched a career as a scientific editor. 

Characteristics and location of extrapelvic endometriosis

The authors of this study reviewed the medical records of 1000 women with endometriosis from two geographical areas, New Haven, US and Crete, Greece over a 20-year period with a goal of identifying the presence and location of extrapelvic endometriosis and its associated characteristics. Extrapelvic endometriosis refers to the endometriotic tissue attached to the areas other than uterus-proximal locations such as ovaries, fallopian tubes, uterine ligaments and the surrounding pelvic peritoneum. Of the 1000 women studied, 200 cases were identified…

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Endometriosis increases the risk of miscarriage

This systematic review was based on four studies in literature and included a total of 31,167 pregnant women with endometriosis. Several studies were previously performed to establish the association between endometriosis and pregnancy loss with contradictory results. This somewhat large data set revealed a higher risk of early miscarriage in spontaneously pregnant (without the aid of medically assisted techniques) women with endometriosis. The authors offered several explanations for the potential association of endometriosis and miscarriage:  (1) Local and systematic inflammation…

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Environmental toxins and endometriosis

Polychlorinated biphenyls (PCBs) are organic chlorine contaminants that were widely used in industry due to their excellent physicochemical properties. However, they were banned in the US and the rest of the world in 1979. PCBs are highly stable and resistant to environmental degradation. Thus, they persist in both the environment and body. PCBs are fat-soluble and may concentrate in the human body through the food chain. This review article from by Yao M et al., from Zhejiang University, China, published…

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Does endometriosis increase skin cancer risk?

Two major types of skin cancer are melanoma, which is the least frequent type but with highest metastatic potential; and non-melanoma skin cancers which include basal cell carcinoma and squamous cell carcinoma. Several risk factors are identified for skin cancer – sun exposure, family history of skin cancer, genetics, etc. Recent studies also suggested that a history of endometriosis increases the risk of melanoma skin cancer. Farland and colleagues extend these studies to examine the association between endometriosis and the…

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Surgical treatment of colonic endometriosis

In this study, the authors provide a brief report published in the journal "The American Surgeon" which retrospectively reviewed the therapy outcomes in eight consecutive patients who had a laparoscopic surgical intervention for deeply infiltrating endometriosis (DIE) at Anne Arundel Medical Center. The goal was to compare "segmental bowel resection" or "excision of local lesions" for colonic endometriosis in terms of therapy and quality of life outcomes. All eight patients had undergone extensive preoperative workup including prior diagnostic laparoscopies as well as CT…

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Women with endometriosis suffer from anxiety and depression

Endometriosis is considered a disabling condition that may significantly affect social relationships, sexuality and mental health of patients. Women who suffer from endometriosis report high levels of anxiety and depression and other psychological disorders. In this review article, the authors discuss the impact of anxiety and depression in the management of endometriosis in affected women. Several studies have found an association between endometriosis and psychological diseases; depression and anxiety are the most common ones. These psychological diseases influence the severity…

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How rats can help improve colon endometriosis treatment in humans

Colorectal endometriosis forms about 3–37% of all deep infiltrating endometriosis (DIE) cases. DIE is a highly invasive type of endometriosis, occurs when ovarian endometriomas overgrow and rupture, releasing their contents into the abdominal and pelvic cavity, resulting in the formation of new lesions of endometriosis outside of ovaries. The management of DIE in the colon is mainly surgical, either the endometriotic nodule in the colon is excised by shaving or the segment of the affected colon is removed altogether. Removal…

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