Nadire Duru, PhD

Nadire is a Research Associate at the University of Maryland, School of Medicine working on finding novel therapeutics to target ovarian cancer. She holds a BS degree in Molecular Biology and Genetics from Istanbul Technical University; an MS degree in Human Genetics from Boğaziçi University; and a PhD in Radiation Oncology from Purdue University. She trained as a post-doctoral scholar at the Lawrence Berkeley National Laboratory and University of California, Davis (UC Davis) before starting her position at the University of Maryland.

Clinical Evaluation of Endometriosis-Associated Pain

Endometriosis has a noteworthy impact on the quality of life of the patients diagnosed with it since it is associated with unpleasant conditions such as endometriosis-associated pain. The diagnosis of endometriosis is not always straightforward because of the varying symptoms and a wide range of clinical manifestations. Median delay for the diagnosis can be as late as 10 years and the delay in diagnosis was found to be longer for women who have pelvic pain compared to women who have…

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Integrated bioinformatic analysis for endometriosis diagnosis

Endometriosis is considered as a non-malignant disease, but it is associated with several unfavorable conditions including non‑menstrual pelvic pain and infertility. Surgical resection and hormone suppression are common means of treatments; however, several side-effects and the recurrence are not preventable. There is an unmet need for developing therapeutic strategies by elucidating molecular mechanisms associated with endometriosis. It is suggested that endometrium of women with endometriosis display an irregular molecular expression pattern, which might help the tissue with implantation, invasion, and…

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Role of miR-141 in endometriosis

MicroRNAs (miRNAs) are short (18–24 nucleotides) endogenous non-coding RNAs that regulate a broad range of signaling pathways. They bind to specific sequences resulting in mRNA degradation and protein inhibition. Deregulation of miRNAs is associated with the development of many disease conditions, one of which is endometriosis. Epithelial-to-mesenchymal transition (EMT), which is considered as one of the hallmarks of cancer metastasis is the process of conversion of epithelial cells to mesenchymal cells, which increase the motility and invasiveness of cancer cells…

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