Selma Oransay, MD

Dr. ORANSAY is 35 years experienced clinician in OB/ GYN. She worked in the main national maternity educational hospital of Turkey for 20 years than she moved to İstanbul and worked in private hospitals. Her published articles are mostly on topics of menopause and infertility. She is also experienced as a voluntary OB/GYN doctor in African healthcare program.

The Relationship Between Dyspareunia and Infertility in Endometriosis

Wahl et al. from the Center of Pelvic Pain and Endometriosis British Columbia Women's Hospital, Vancouver, Canada studied with endometriotic patients suffering from dyspareunia who were referred to their center and built a cross-sectional study to investigate the relations between dyspareunia symptoms with infertility. Their results were published recently in "Sexual Medicine". The authors hypothesized that both deep dyspareunia and superficial dyspareunia would be independently associated with infertility concerns among women with endometriosis. However, only superficial dyspareunia found to be…

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Diaphragmatic endometriosis

Diaphragmatic endometriosis is a rare clinical condition that may show signs and symptoms like chest pain, right upper quadrant abdominal pain, shoulder pain, pleuritic pain, hemothorax, pneumothorax, hemoptysis, and thoracic endometriosis syndrome while the major part of the patients is asymptomatic (70%). The clinical diagnosis of this form of endometriosis is difficult due to the low sensitivity of imaging techniques and the lack of symptoms in most of the patients.  To reveal the feasibility, safety, and effectiveness of the minimally…

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Adiposity, endometriosis type and severity

Dr. Jiyoung from the division of Public Health, Department of Family and Preventive Medicine of the University of Utah, planned a prospective cross-sectional study to assess whether there is an inverse relationship between the adiposity and endometriosis. The results of the study are published in the "Journal of Minimal İnvasive Gynecology". To reveal that if adiposity is a risk factor for initiating endometriosis, 495 women from 14 clinical centers in Salt Lake City, Utah and San Francisco California, were enrolled…

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Treatment choices for abdominal wall endometriosis

Welch et.al, from the Department of  Radiology, Mayo Clinic, Rochester, worked with his gynecologist colleagues to underline the current treatment algorithm of abdominal wall endometriosis in Mayo Clinic. Their experience results recently published in the journal "Abdominal Radiology". Abdominal wall endometriosis diagnosis is frequently delayed due to other causes of abdominal pain, like hernias that occurred after abdominal operations, and tend to be increased by the increasing rate of cesarean section deliveries. When the diagnosis of abdominal wall endometriosis has…

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Rare lesions in the pathologic examinations of endometriosis.

Dr. Glenn McCluggage from the Department of Pathology, Belfast Health, and Social Care Trust, penned a review about selected uncommon variants of endometriosis or benign alterations that may cause difficulties of pathologic diagnosis and provided all related histopathological illustrations in a recent periodical of Histopathology. The potency of some endometriosis undergoing a malignant transformation like ovarian clear cell carcinoma and endometrioid is well known. Besides them, uncommon tumor types that may arise in endometriosis also be under debate. The author…

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Endometriosis and atherosclerotic cardiovascular disease

Endometriosis and atherosclerotic cardiovascular disease show the same pathologic mechanism in terms of endothelial dysfunction. Tan et al. from the Department of Obstetrics and Gynecology, the University of British Columbia, Vancouver, Canada reviewed the literature aiming to determine whether women with endometriosis are candidates of the high-risk population for lifelong atherosclerotic cardiovascular diseases. Their paper is recently published in the journal named "Reproductive Biomed Online". The diagnosis of endometriosis in women is made in their premenopausal years that makes the…

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How to design patient-centered interventions to meet the needs of endometriosis patients

The treatment of endometriosis is not perfect and necessitates the development of patient-oriented care initiatives. On this basis, patient-related transparent information should be the priority for researchers to find out a way for targeted interventions. Steele et al. from Australia and New Zeland, wrote an opinion paper to explain what is necessary to find an answer to the needs of patients with endometriosis. The paper is recently published in the journal "Australian and New Zeland Obstetrics and Gynecology". When the progression…

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Surgery and the endometriosis associated-pain: A systematic review

The surgical approach for pelvic pain-related to endometriosis depends on the stage and the type of the endometriotic lesion and ranging from ablation and the excision of the lesions to radical surgery as hysterectomy with removal of ovaries and presacral neurectomy. Although in clinical research, no improvement in pain-relief after surgery reported in 20-38% of the patients, preferred conservative surgery for endometriosis remains as protection of the uterus and at least one ovary. Singh et al. from the Department of…

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Risk of placenta previa is elevated in endometriotic women who underwent surgery.

In the last decade concerns raised for surgical operations performed before pregnancies of endometriotic patients due to significantly increased risk of pregnancy complications such as placenta previa, preterm birth, hypertensive disorders of pregnancy, placental abruption, postpartum hemorrhage and small baby for gestational age. The comparison of the efficiency of medical treatment versus surgery before pregnancy remains uncertain. To evaluate the difference between these two regimes affecting perinatal outcomes, Miura et al. from the Department of Obstetrics and Gynecology of Nagoya…

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Cloverleaf Sign: A new MRI sign for diagnosing DIE

Magnetic resonance imaging provides accurate information for the staging of deeply infiltrating endometriosis, especially when the patient is virgin, obese or has limited transvaginal examinations due to pelvic pain. In this recently published study in Investive Radiology, Harma et al. from the University of Bern, Switzerland aimed to evaluate the role of an MRI "cloverleaf" sign as a tool to improve the diagnosis of deep infiltrating endometriosis and to compare related operative findings. Their retrospective study group consists of 103 patients. Two…

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Increased obstetrical complications after ART therapy in endometriosis patients.

To examine the impact of endometriosis and adenomyosis on ART therapy, Harada et al. from the Department of Obstetrics and Gynecology of Tottori University, Japan, planned a prospective cohort study and published their results recently in PLoS One.  The study pool consists of 103.099 pregnancies that resulted in live-birth, stillbirth or abortion between February 2011 and July 2014 on 15 different regions of Japan. The presence of adenomyosis or endometriosis in these patients was based on the responses to a…

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Consquences of endometriosis in menopausal period.

Marie-Scemama et al. from Foch Hospital, Suresnes, France, referred to endometriosis and menopause which is an actual cruising topic and recently published it in the journal named "Hormone Molecular Biology and Clinical Investigation". Endometriosis a well-known estrogen-dependent disease has three distinct phenotypes: Superficial peritoneal endometriosis, ovarian endometrioma, and deeply infiltrated endometriosis. Moreover, this disorder frequently associated with adenomyosis. The mystery about the development of endometriosis is why different forms of the disease are presented in different patients or why all types…

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A new technique for laparoscopic management of ovarian endometriosis.

To cause a minimal hazardous effect on ovarian reserve during laparoscopic surgery of endometriomas is always a great concern for clinicians. Shaltout et al. from Cairo University, Egypt, examined the effect of "Surgicel" on preventing the recurrence of endometriomas and recently published their results in the "Journal of Ovarian Research". Surgicel, an oxidized regenerated cellulose compound, acts as a physical barrier that stimulates platelet aggregation and clotting, while it's acidic nature helps to create vasoconstriction at the application area to…

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Endometriosis and the quality of life

Recent developments of technics and improvement of skill in the laparoscopic field increased the courage of clinicians to attempt early and multiple diagnostic operations on endometriotic patients. Vanuccini et al. from NEUROFARBA, University of Florence, Florence, Italy recently published their prospective study aimed to evaluate the relation between early laparoscopy and further quality of life in endometriosis, in the "Journal of Gynecological Endocrinology". After applying the Questionnaires and  SF12 (Short Form 12)  to a total number of 153 patients, two…

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Adolescent dysmenorrhea and future endometriosis

Dysmenorrhoea is typically classified as primary, or secondary due to underlying pathologies like fibroids, endometriosis, adenomyosis or uterine anomalies. Generally, long-term dysmenorrhea is present in endometriotic patient's anamnesis, but until recently, the research to clarify this connection remained retrospective. Knox et al. from the Department of Paediatric and Adolescent Gynecology, The Royal Children's Hospital, Melbourne, Australia, conducted a longitudinal cohort study on adolescents who need multiple treatments in tertiary centers due to their severe dysmenorrhea, aiming to find the relation between…

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What happens to women with endometriosis after menopause?

Endometriosis affects women in their reproductive period of life, with expected regression of lesions in the postmenopausal period. Literature about postmenopausal endometriosis assessing the prevalence, pathogenesis, and treatment is limited. As 2-5 % of postmenopausal women are affected by this uncommon condition, developing stress push forward the necessity for future research on this topic. Ladanyi et al. from the Department of Obstetrics and Gynecology from the University of Tennessee, USA, reviewed the current literature and recently published their findings regarding postmenopausal endometriosis in the…

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How to Classify Endometriosis for a better and effective evaluation

Endometriosis affects 10% of women in their reproductive period and causes infertility around 40% of women who have the disease. Peritoneal fluid may be one of the factors to facilitate the spread of endometriosis to ovaries, peritoneum and other deep tissues. Small, but progressive lesions may progress more aggressively inside the pelvic space and be more harmful to patient fertility when compared to larger but calm masses of endometriomas. Joliniere et al., from the Department of Gynecology and Obstetrics in Fribourg…

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A position statement of diagnosing and treating endometriosis for gynecologists.

Endometriosis Treatment Italian Group recently declared 10 "valuable" conducts to evaluate endometriotic patients and published them in Hum. Reprod. Open. This society consists of 16 university departments and training center with expert clinicians on endometriosis from Italy. After arising the idea of defining medical interventions and achieving gold standards of diagnosing and treating endometriosis that can be adapted to various disease forms they performed first meeting in Oct.2016. In this meeting, the committee discussed and collectively selected the final ten remarks to…

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A study about adnexial torsion doubts in patients with endometriosis.

Endometrioma is the presence of endometriosis cysts in the ovary, and is one of the most common forms of endometriosis, with unknown pathophysiology. Adnexal torsion results in twisting ovarian tissues resulting in a decreased blood flow. The causes for adnexal torsion due endometrioma is not clear yet. Dr. Dafna and colleagues from the Department of Obstetrics and Gynecology of Tel Aviv University, Israel, recently published a retrospective cohort study in Israel Medical Association Journal, where they retrospectively examined the data of surgically…

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Analogous pathways of peritoneal tumor wound healing and endometriosis.

Endometriosis, diagnosed around 10-15% of women population in their reproductive period, is a chronically progressive inflammatory disease to cause peritoneal lesions while spreading into the abdominal cavity. The pathophysiology of the adhesions between the peritoneum and pelvic organs can be explained by the similar pathways of some other clinical conditions such as peritoneal metastasis and injuries, which cause hypoxia, cytokines discharge, fibrosis, and sclerosis of peritoneal tissues. Dr. Wilson, from the Upper Gastrointestinal Surgery Department of Liverpool Hospital, Australia, penned…

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