Özge Özkaya, PhD

Özge has a Phd in Molecular Biology and several years experience working as a bench scientists. She has been working in science communication since 2014.

Potential New Approach to Treat Endometriosis

Inhibiting ribosome biogenesis could be a potential therapeutic approach for endometriosis according to a new study published in the scientific journal Biomedicines. Ribosome biogenesis plays a key role in protein homeostasis during cell growth and division. Previous research has shown that it is upregulated during endometriosis progression and malignant transition. Based on this knowledge, a team of researchers led by Dr. Jim Jinn-Chyuan Sheu hypothesized that inhibiting ribosome biogenesis could be effective for treating the disease and complications associated with…

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Medicinal Cannabis Use for Endometriosis in Australia and New Zeland

Cannabis use leads to positive outcomes for the management of endometriosis according to the results of an online survey among patients from Australia and New Zealand. These findings, which were published in the journal Cannabis and Cannabinoid Research suggest that medicinal cannabis may have a therapeutic potential in endometriosis. However, many patients are using it without medical supervision and this could have detrimental effects, especially in terms of drug interactions and the tapering or cessation of other medications without supervision. …

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Mindfullness Can Hep Reduce Endometriosis Pain

A brief mindfulness-based intervention can be useful in managing pain related to endometriosis and restoring patients’ psychological well-being, found a new study published in the European Journal of Pain. This finding contributes to the applicability of mindfulness-based interventions in people living with chronic pain. Endometriosis can cause debilitating pain and have a great negative impact on the quality of life of women living with it. Although laparoscopic deep excision surgery, the gold standard endometriosis treatment, can alleviate pain symptoms in…

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Quality of Life Is Negatively Correlated With Anxiety and Depression in Endometriosis

The quality of life of endometriosis patients is negatively correlated with anxiety and depression according to a new study published in the scientific journal Frontiers in Psychology. Based on this finding, the authors of the study suggest that improving patients' quality of life may help them “relieve their unhealthy emotions”. In order to analyze the effect of quality of life on unhealthy emotions and identify factors that may be relevant to supporting the clinical care of patients, a team of…

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Challenges of Living With Endometriosis and Possible Solutions

A new study published in the scientific journal BMC Women's Health reviewed the challenges of living with endometriosis and possible solutions for women with the disease. The findings of the study highlight the need for a multidisciplinary approach to treating women with endometriosis.  “To achieve this goal, a collaboration of professionals, psychologists, and support organizations is needed in the near future,” wrote first author Gabriella Márki and the co-authors of the study, for which a team of medical and psychological…

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Imaging Techniques Able to Predict Depth of Endometriosis Before Surgery

Transvaginal ultrasound (TVUS) and pelvic magnetic resonance imaging (MRI) performed by a specialist can accurately predict the depth of rectosigmoid endometriosis before surgery, according to a new study published in the Journal of Minimally Invasive Gynecology. Both approaches are similar in assessing the depth of rectal wall involvement, according to the authors of the study who said that “their use is justified in the preoperative planning of these gynecologic surgeries”. It is still very difficult to diagnose and assess the…

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A New Non-Invasive Marker for Endometriosis?

The reactivity of serum immunoglobulin G (IgG) with fucose-specific lectins AAL, LCA, and LTA could be a useful diagnostic biomarker for endometriosis, according to a new study published in the Journal of Inflammation Research. It could also be a clinical tool to differentiate women with advanced endometriosis from those without the disease. “… the analysis of native IgG fucosylation directly in serum, without prior time-consuming, expensive IgG isolation, is sufficient to distinguish advanced stages of endometriosis from a control group…

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Could Traditional Chinese Medicine Treat Endometriosis?

Tetramethylpyrazine, a compound derived from a herb and used in traditional Chinese medicine could be a promising drug candidate to treat endometriosis. This is according to a new study by Dr. Shenghui Huang and colleagues published in the scientific journal Reproductive Sciences.  Researchers increasingly think that endometrial lesions are wounds that undergo repeat cycles of tissue repair and injury. Platelets, therefore, play a crucial role in the progression of the disease. Tetramethylpyrazin has been used in traditional Chinese medicine for thousands…

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Surgery for the Treatment of Endometriosis of the Diaphragm and Thorax

Diaphragmatic and thoracic endometriosis starts in the abdominal wall of the diaphragm and later invades the thorax, based on findings from a series of patients surgically treated for the disease, reports a study published in the Journal of Gynecology Obstetrics and Human Reproduction.  Therefore, early diagnosis is of great importance, according to Dr. Alexia Wetzel and the co-others of the study who stress that chest pain should be systematically investigated in patients experiencing pelvic endometriosis. To review the current management…

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Endometriosis of the Diaphragm, What do the Doctors Know About it?

The median time between the first consultation with a primary care physician and receiving a diagnosis of endometriosis of the diaphragm is two years according to a study by U.K. researchers. In the worse case, it took 23 years for a patient to receive a diagnosis, the study found. The reason for the delay is a lack of awareness among patients and healthcare professionals, according to Rachel Piccus and the co-authors of the study. “ The diagnosis of [diaphragmatic endometriosis]…

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Effects of Bowel Endometriosis Surgery on Mode of Delivery

Less than a third of doctors counsel women about the possible effects of surgical treatment of bowel endometriosis on their mode of delivery should they become pregnant, according to a new study published in the Journal of Obstetrics and Gynaecology. “Our survey highlights [the] wide variation in practice that currently exists,” wrote the authors of the study and said that guidance from the European Society of Gastrointestinal Endoscopy and/or The British Society for Gynaecological Endoscopy (BSGE) could help clinicians counsel…

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Pain During Intercourse, What Does it Feel Like?

The presentation, severity, and impact of painful intercourse caused by endometriosis differ between patients, found a new study published in The Journal of Sexual Medicine. According to the authors of the study, these findings are important because they can help develop better patient-reported outcome measures of this symptom. Dyspareunia or painful intercourse is one of the 5 main symptoms of endometriosis. Despite the fact that it can have a considerable impact on a woman’s quality of life and relationships, endometriosis-associated…

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Endometriosis Seems to Affect The Development of the Embryo

Embryos development is impaired in embryos from women with endometriosis found a new study published in the Journal of Assisted Reproduction and Genetics. In spite of this, the outcomes of in vitro fertilization (IVF) are similar for patients with endometriosis and women without the disease. In order to compare the development of embryos obtained from women with endometriosis and those without, a team of researchers led by Dr. Nina Desai from the Department of Obstetrics and Gynecology, Division of Reproductive…

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A New Simultaneous Tool to Assess Endometriosis Symptoms

Researchers from the Netherlands developed a new digital tool to assess the symptoms of endometriosis using the experience sampling method. This new method may help overcome the limitations of current questionnaires.  “After validation and testing, future studies will be planned to evaluate the use of this tool in a clinical setting in order to propose a personalized treatment plan for women with endometriosis,” wrote the researchers in an article they published in JMIR Formative Research. The symptoms of endometriosis have…

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How Likely Am I to Conceive After Endometriosis Surgery?

Women with superficial peritoneal endometriosis and just one type of lesion are more likely to conceive after surgery, according to a new study published in the International Journal of Gynecology and Obstetrics.  This is important because patients will be better informed and will have a clearer idea of what they can expect following surgery in terms of fertility. In order to characterize the relationship between the type of endometriosis lesion and the rate of conception following surgery in infertile women…

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Importance of Language in Communicating Endometriosis Pain

Language is of great importance for women with endometriosis to communicate their pain to their doctor, according to a new study published in Frontiers in Global Women's Health. The study also found that additional tools are needed to help women and doctors find the most effective way to communicate the experience. In order to examine the role of language in doctor-patient communication and what patients and doctors consider challenging and effective in endometriosis pain communication, Drs Stella Bullo and Annalise…

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New Endometriosis Clinical Trial Now Recruiting Participants

A new clinical trial investigating the effect of cognitive-behavioral therapy on quality of life in patients undergoing surgery for endometriosis is now recruiting participants. The randomized, controlled trial aims to recruit 100 participants, ages 18 to 50 with proven endometriosis and an indication for endometriosis debulking surgery. The participants will be divided into two groups. Those in the first group will receive usual care after the surgery while those in the second group will receive usual care plus cognitive-behavioral therapy.…

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Endometriosis and Sex

The sexual quality of life of women with adenomyosis or deep infiltrating endometriosis is significantly worse than that of women without the diseases, according to a new study published in the Journal of Sex & Marital Therapy. This finding suggests that adenomyosis and deep infiltrating endometriosis may have a negative impact on couples’ sexual life and relationships.  According to the authors of the study, clinicians should be aware of this problem when treating women with either disease. “The mere fact…

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Effects of Hormonal Contraceptives on Endometriosis Pain

There is no difference between the oral progestin dienogest and combined oral contraceptive pills in managing pain and increasing quality of life in women with endometriosis, according to the results of a randomized, double-blind, placebo-controlled clinical trial. However, there was a significant difference between treated patients and those who received a placebo. Combined oral contraceptive pills are readily used to manage the symptoms of endometriosis however, their effectiveness has not been thoroughly investigated. Here, a team of researchers led by…

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Pain During Sex in Women With Endometriosis

Pain during intercourse or dyspareunia due to endometriosis manifests itself in multiple forms such as deep, introital, and/or positional. Pain can also occur at orgasm and during and/or after intercourse. These are the findings of a systemic literature review published in the International Journal of Environmental Research and Public Health. “Dyspareunia impairs women's psychological health, especially in terms of poor self-esteem and sense of femininity, and has negative consequences on intimate relationships,” the researchers wrote. However, despite this, both women…

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