Özge Özkaya, PhD

Özge has a Phd in Molecular Biology and several years experience working as a bench scientists. She has been working in science communication since 2014.

New Approach could help Preoperative Differentiation of Endometriosis and Cancer

Researchers in Japan identified some radiological parameters that could be used to differentiate between endometriosis-associated ovarian cancer (EAOC) and a particular type of benign ovarian endometriosis (OE), making it easier for doctors to offer the right treatment to women who need it. In a research article published in the scientific journal Magnetic Resonance in Medical Sciences, a team of researchers led by Dr. Hiroshi Kobayashi reported that the height and height-width ration (HWR) of the mural nodules, or cysts found…

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Best Time for IVF Between 7 and 25 Months Post Surgery Study Suggests

The more severe endometriosis is, the lower the success rate of IVF, according to a new study published in the Journal of Minimally Invasive Gynecology. However, the presence of endometriosis as such does not seem to affect the outcome of IVF and the best time to have IVF seems to be seven to 25 months after endometriosis surgery. In order to evaluate the impact of endometriosis on the outcome of IVF and to identify the best time interval to have…

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Cystectomy More Likely to Cause Infertility than Laparoscopic Vaporization

Treating patients with endometriotic ovarian cysts using laparoscopic vaporization may be better than treating them with cystectomy, or the surgical removal of cysts, regarding fertility. This information is according to a study conducted by Japanese scientists and published in the Asian Journal of Endoscopic Surgery. Although both operations can lower the ovarian reserve, or the capacity of the ovary to provide eggs that can be fertilized leading to a successful pregnancy, laparoscopic vaporization seems to be associated with a slower rate…

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Interleukin-6 Involved in the Development of Endometriosis

A chemical produced by the body called Interleukin-6 (IL-6) and known to be involved in inflammation also seems to promote the development of endometriosis. This is according to a study by Chinese scientists published in the journal Medical Science Monitor. Previous research has shown that the concentration of IL-6 is increased in the peritoneal fluid (the liquid lubricating the surface of tissues lining the abdominal wall and pelvic cavity) of women with endometriosis. But it was not clear whether increased…

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Plant Compound May Protect Against Endometriosis

Marrubiin, a compound derived from a plant in the mint family called white horehound may have protective effects against endometriosis, according to a study published in the journal Molecular Medicine Reports.  Marrubiin is the main analgesic, or painkiller compound found in the white horehound and is used to treat several ailments. It is known to improve blood and lymph flow, has anti‑inflammatory and anti‑oxidative properties, and may protect the heart muscle. In order to assess whether marrubiin may also have…

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Women with Deep Infiltrating Endometriosis Have a Higher Risk of Appendix Involvement

Women with deep-infiltrating endometriosis, a form of endometriosis that invades the abdominal and pelvic cavity, have an increased risk of developing endometriosis of the appendix. It is therefore important to check women with deep infiltrating endometriosis for appendix involvement during endometriosis surgery in these patients. Researchers from the University of North Carolina, Chapel Hill, NC, USA, led by Dr. Joanne Garrett, conducted a study to determine whether women with deep infiltrating endometriosis have an increased risk of appendiceal endometriosis compared to…

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Indirect assessment of endometriosis prevalence in general population

The prevalence of endometriosis is 10 percent among the general population, estimates a study published in the Journal of Gynecology Obstetrics and Human Reproduction. It is very difficult to estimate the prevalence of endometriosis in the general population. Seventeen different research articles have been published assessing the prevalence of endometriosis in women undergoing tubal sterilization. The results of these studies showed a huge variation in the prevalence of endometriosis ranging from 1.4 percent to 43.3 percent.   In order to…

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Bowel Involvement in Deep Infiltrating Endometriosis

Cleansing the colon before an ultrasound makes it easier to detect rectal nodules of deep infiltrating endometriosis, found a study published in the Journal of Minimally Invasive Gynecology.  Cleansing the colon before a surgery is called bowel preparation and is done using drugs that cause diarrhea, therefore, emptying the colon.  Researchers led by Dr. Francisco Carmona at Universitat de Barcelona in Spain wanted to assess whether bowel preparation increases the accuracy of transvaginal ultrasound, an ultrasound done by inserting the…

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"Kissing Round Ligaments" May Be a Sign of Bladder Endometriosis

Specific laparoscopic findings may help surgeons diagnose bladder endometriosis, a rare and often undiagnosed condition.  Bladder endometriosis is thought to affect only around one percent of patients with endometriosis. However, this could be an underestimation and many cases may go undiagnosed. In order to help surgeons diagnose bladder endometriosis, researchers led by Dr. David Soriano in the Department of Obstetrics and Gynecology, at The Chaim Sheba Medical Center in Ramat-Gan, Israel established a visual score of pelvic lesions.  The team…

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The Involvement of the Blood Clotting System in Endometriosis

The blood clotting system might be over-active in women with endometriosis, found a study published in the scientific journal Reproductive Sciences.  Although the authors stated that there is not enough evidence to suggest that over-coagulation may be directly causing endometriosis or that the clotting status can be used as a tool to diagnose the disease they noted: “A role of the local coagulation system in the pathogenesis of the disease cannot be excluded.” In order to assess whether there are…

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The Most Cost Effective Medical Treatment to Prevent Recurrent Endometriosis

A new study conducted in China found that a class of drugs called Gonadotropin-releasing hormone agonists (GnRH-a) is more cost effective for the treatment of recurrent endometriosis despite the fact that they are more expensive than oral contraceptives. The results of the study published in An International Journal of Obstetrics & Gynaecology could help clinicians and patients worldwide to decide which drug to choose as a first-line treatment for the prevention of endometriosis. Researchers led by Dr. Yu Wang at …

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Symptoms of Endometriosis May Be Partly Caused by an Infection and Be Treated with Antibiotics

Women with endometriosis are more frequently diagnosed with chronic endometritis compared to other women found a study published in the medical journal Fertility and Sterility.  According to the authors, this finding suggests that although no causal relationship between these two conditions has been established, chronic endometritis should be considered in women with endometriosis especially if they have abnormal bleeding. This way they can be treated with appropriate medication and unnecessary surgery could be avoided. Chronic endometritis is a chronic inflammation…

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Naturally Occurring Plant Product May Hold Promise for the Treatment of Endometriosis

A natural plant product called apigenin might be a potential new treatment for endometriosis according to a study published in the Journal of Cell Physiology. “ […] Apigenin is a potential novel therapeutic agent to overcome current limitations in the treatment to endometriosis,” the researchers wrote but added that further research using animal models are required before apigenin can be considered for the treatment of endometriosis patients. Apigenin is a compound found in several fruits and vegetables such as parsley,…

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Novel Biological Pathway Could Offer new Treatment Option for Endometriosis

Researchers have identified a novel biological pathway that may be involved in endometriosis. Targeting this pathway may, therefore, be a new alternative approach to treating the condition in the future.  Endometriosis is characterized by the tissue that normally lines the walls of the uterus to grow in the peritoneum, or space lining the inside of the abdomen causing pain and even infertility. However, there is very little oxygen in this area, and therefore it is usually not an environment that…

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Robotic Assisted Laparoscopy Not Better Than Standard Laparoscopy

Robotic-assisted laparoscopy (RAL) does not seem to offer any benefits over standard laparoscopy, according to a study published in the scientific journal Reproductive Biomedicine Online.  According to the authors of the study more research is needed to investigate the role of RAL for the treatment of endometriosis. “Due to the higher costs, RAL treatment of endometriosis should be performed only within controlled studies,” the researchers wrote.  In order to clarify whether RAL, which became available in recent years, offers an…

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The Endometrium Itself is Genetically Different in Endometriosis Patients

Researchers in China identified a number of genes that are differentially expressed in the eutopic endometrium of women with endometriosis and those without. The researchers think that these genes may be involved in the development of endometriosis and that they may be useful as potential biomarkers to for the diagnosis of the condition. For the study that was published in the scientific journal Biomedical Reports, the team led by Dr. Yuanguang Meng at People's Liberation Army Medical School in Beijing,…

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Female Sex Hormone Necessary but not Enough to Cause Endometriosis

Estrogen, the primary female sex hormone may be necessary but is not enough to induce endometriosis, found a study published in the Journal of Bioscience.   This finding is important because it can help scientists better understand factors that cause endometriosis and design new approaches to treat it.  It is known that estrogen is one of the factors that cause endometriosis. In order to better understand the role of this hormone in the development of the disease, researchers at the National…

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Asian Women at Higher Risk of Endometriosis and Less Likely to Conceive with IVF but not Because of their Endometriosis

The rate of endometriosis is higher amongst women of Asian origin confirms a study published in the Journal of Assisted Reproduction and Genetics. In addition, pregnancy rates following fertility treatments are lower in this group of women. However, this does not seem to be related to their endometriosis. In order to determine whether being diagnosed with endometriosis had an influence on the outcome of IVF treatment in women from different ethnic backgrounds, researchers at the University of California, in collaboration…

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TFF3 May Be Involved in Endometriosis Research Suggests

Levels of a protein called TFF3 are significantly increased in the peritoneal cavity (the abdominal space) of women with endometriosis, found a study published in the scientific journal Reproductive Sciences. This increase was in line with levels of other known biomarkers of endometriosis such as cancer antigen (CA) 125, CA-19-9, interleukin 8, monocyte chemotactic protein 1, and matrix metalloproteinase 7. In addition, the levels of the TFF3 protein in the blood of women were significantly influenced by the menstrual cycle…

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A Cholesterol-Lowering Drug and an Anticancer Drug May Be Alternative Treatments Against Endometriosis

Crestor (rosuvastatin), a cholesterol lowering drug and Avastin (bevacizumab), an anticancer drug are more efficient in reducing endometriosis in rats compared to progesterone medication, according to a study published in the journal Gynecological Endocrinology. For the study, researchers led by Dr. Cetin Celik at the Department of gynecology and obstetrics at Selcuk University in Konya, Turkey induced endometriosis in rats by surgically implanting endometriotic tissue in their abdomen. They then separated the rats into three groups of 10 animals each.…

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