Özge Özkaya, PhD

Özge has a Phd in Molecular Biology and several years experience working as a bench scientists. She has been working in science communication since 2014.

Effects of Hormonal Contraceptives on Endometriosis Pain

There is no difference between the oral progestin dienogest and combined oral contraceptive pills in managing pain and increasing quality of life in women with endometriosis, according to the results of a randomized, double-blind, placebo-controlled clinical trial. However, there was a significant difference between treated patients and those who received a placebo. Combined oral contraceptive pills are readily used to manage the symptoms of endometriosis however, their effectiveness has not been thoroughly investigated. Here, a team of researchers led by…

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Pain During Sex in Women With Endometriosis

Pain during intercourse or dyspareunia due to endometriosis manifests itself in multiple forms such as deep, introital, and/or positional. Pain can also occur at orgasm and during and/or after intercourse. These are the findings of a systemic literature review published in the International Journal of Environmental Research and Public Health. “Dyspareunia impairs women's psychological health, especially in terms of poor self-esteem and sense of femininity, and has negative consequences on intimate relationships,” the researchers wrote. However, despite this, both women…

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Sexual Function in Women With Endometriosis

The sexual function of women diagnosed with endometriosis is impaired confirmed a new study by Spanish researchers published in the Journal of Clinical Medicine. According to the study, the strongest predictive factors for poor sexual function are deep disease, depression, age, and unemployment. Sexual function is defined as the way the body reacts in different stages of the sexual response cycle. Recent research has shown that endometriosis has a negative impact on a woman’s sexual quality of life. The disease…

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Antinuclear Antibody May Be Linked to Milder Disease in Endometriosis

The prevalence of positive antinuclear antibody was 21.2% in women with endometriosis compared to 5.4% in controls, according to a new study published in the journal Human Immunology. Antinuclear antibodies are autoantibodies that bind to the content of the cell nucleus. Interestingly, patients with positive antinuclear antibody were more likely to have no symptoms and had less painful menstruation. “The presence of this autoantibody may be linked to a milder clinical expression of the disease,” wrote the authors of the…

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Does Surgery Improve the Digestive Symptoms of Endometriosis?

Women with deep infiltrating endometriosis involving the bowels have the most significant improvement in gastrointestinal symptoms following surgery. This is according to the findings of a comparative retrospective study in almost 1,500 women.  “Women with severe bowel symptoms and deep endometriosis infiltrating the bowel should be informed about the high probability of symptom improvement after the removal of bowel nodules,” wrote the authors of the study that was published in the Journal of Minimally Invasive Gynecology. The researchers’ aim was…

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Dietary adjustments do not increase the quality of life of women with endometriosis.

Even though dietary changes do not seem to increase patients’ quality of life, they lead to a perceived reduction in symptoms. No specific adjustment in the diet increases the quality of life of women with endometriosis, according to a new study by Dutch scientists. However, patients with the disease do feel that adjustments to their diet improve their symptoms. “(…) more research is needed to gain evidence about the specific effects of nutrients on endometriosis symptoms,” wrote Iris Krabbenborg and…

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Could Cannabis Be Recommended to Manage Endometriosis?

It is not possible to recommend cannabis-based products to patients with endometriosis because there is not enough evidence supporting their benefits, according to a new study published in the Journal of Minimally Invasive Gynecology. Cannabis-based products have been suggested as a therapeutic option for patients with endometriosis. They could overcome the disadvantages of current treatments such as infertility and other side effects, it was proposed. In order to understand the effects of cannabis-based products on women’s reproductive system and establish…

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Endometriosis Increases the Risk of Premature Labor Study Reports

Women with endometriosis who conceive naturally are at a high risk of giving birth prematurely and having their baby admitted to neonatal intensive care unit, compared to women without the disease, according to the results of a clinical study. The study also showed that women with severe adenomyosis in addition to endometriosis have a higher risk of placenta previa, where the placenta grows in the lowest part of the uterus, and the need to have a Cesarean section. This finding…

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The Coping Strategies of Korean Women With Endometriosis

Women with endometriosis adopt four main strategies to cope with the disease, according to a new study published in the journal "Research in Nursing & Health". These are gaining self-control, regaining daily routines, being emotionally supported and expressing themselves when feeling unsupported by society, and taking an active role in their own treatment plan. “This paper has widespread implications, including the need for training or a continuing education program for health professionals to enhance their competencies when caring for women…

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How to Reduce Pain After Laparoscopic Surgery

Using humidified warm gas with forced-air warming blanket during laparoscopic surgery resulted in significantly less pain in the recovery room, according to a new study published in the journal "Surgical Endoscopy". In patients with endometriosis, using humidified warm air even without forced-air warming blanket resulted in significantly less pain compared to insufflation with dry cold CO2 with forced-air warming blanket. “(…) in predisposed patients with endometriosis and who could otherwise expect high pain levels, warm and humidified gas may be…

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The Cost of Healthcare for Chronic Pelvic Pain

The healthcare costs of pelvic pain range between 1,367 USD and 7,043 USD per woman per year, found a new study published in the Journal of Obstetrics and Gynaecology Canada. The study also reported that prescription costs ranged between 193 USD and 2,457 USD and indirect costs ranged between 4,216 USD and 12,789 USD per woman per year. Combined costs ranged between 1,820 USD and 20,898 USD. When the researchers analyzed the yearly costs of chronic pelvic pain by country,…

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Potential new Target to Reduce Endometriosis Pain

The inflammatory mediators, bradykinin, and bradykinin B1 receptor may play a role in the onset of endometriosis-associated pain according to a new study by Chinese researchers. They do so by inducing the prostaglandin signaling pathway. Therefore, targeting these biological pathways could be a new therapeutic approach for endometriosis and increase patients’ quality of life. Although pain is one of the main symptoms of endometriosis researchers do not fully understand its exact cause and mechanism in the disease. However, they know…

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Research Identifies New Genes That Could Be Targeted to Treat Endometriosis

Researchers identified three new genes that could help understand the invasiveness of endometriosis. They also identified one new gene that could be related to the recurrence of the disease. These genes may potentially be new therapeutic targets for endometriosis. In order to find new biomarkers and therapies for endometriosis, two researchers from the University of Science and Technology in Wuhan, China, researchers analyzed the common characteristics of endometriosis and endometriosis-related type ovarian cancer by screening differentially expressed genes between the…

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Impact of Endometriosis on Work Life in Finnish Women

Endometriosis is associated with poor "work ability" at late fertile age, according to a Finnish study published in the journal Acta Obstetricia et Gynecologica Scandinavica. Although women with endometriosis have more disability days, their employment rate and risk of early retirement are similar to those without the disease at late fertile age, the study found. Based on these findings, the authors encourage healthcare practitioners to recognize the relevance of organizing timely care for endometriosis patients to promote their "work ability". …

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Ovarian Cancer Survival in the presence of Endometriosis

Women with ovarian cancer and histologically proven endometriosis have longer overall survival compared to those with ovarian cancer but no endometriosis, found a study published in the American Journal of Obstetrics & Gynecology.  “[…] Women diagnosed as having ovarian cancer and concurrent endometriosis should be explained the role of endometriosis in ovarian cancer survival,” the authors of the study wrote. They added that future studies on the treatment and prognosis of ovarian cancer should consider stratifying patients by endometriosis status…

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Depression and Anxiety Common in Women with Endo

Symptoms of depression and anxiety are frequent among women with endometriosis and are related to chronic pain, confirms a review of the literature and meta-analysis published in the Journal of Women's Health.  According to the study authors, correlating factors should be investigated further. Researchers have suggested that the symptoms of endometriosis such as chronic pelvic pain are associated with psychological distress in women with the disease. In order to explore the strength of the associations between endometriosis and depression or…

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Chemical Found in Self-Care Products May Be Linked to Endometriosis

There may be a link between exposure to phthalates and endometriosis according to a new study published in the Journal of Assisted Reproduction and Genetics. Although more research is needed, these findings could be translated into clinical practice according to Dr. Alessandro Conforti and the co-authors of the study. Phthalates often called "plasticizers" are a group of chemicals used to make plastics more durable. They are widely used in many products including vinyl flooring, lubricating oils, and personal-care products such…

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Technical Facts for the Prevention of Complications After Deep Endometriosis Surgery

There are no differences in the risk of rectovaginal fistula in women with rectovaginal endometriosis who were managed by a liberal or restrictive policy of preventive stoma according to a study by French researchers published in the Journal of Minimally Invasive Gynecology. According to the authors, this result suggests that stomas should not be routinely performed in women with rectal and vaginal sutures. Instead, they should be carefully evaluated based on risk factors such as distance from the anal verge.…

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Strong Geographical Gradient in Endometriosis Incidence Identified

The geographical distribution of new endometriosis cases showed a very strong north-south spatial gradient in the highly industrialized Friuli Venezia Giulia region of Italy, according to a new study published in the International Journal of Environmental Research and Public Health. “The cluster of 5 municipalities in the industrialized and polluted south-east part of the region is suggestive,” the researchers wrote. But they said information about patients' characteristics and exposure histories are limited due to the ecologic nature of the study. The incidence estimates…

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Endometriosis and Rheumatoid Arthritis, Could There Be a Link?

Patients with endometriosis have a higher risk of rheumatoid arthritis according to a study published in the journal Rheumatology. This finding suggests that rheumatologists should be especially mindful of the possibility of underlying endometriosis when treating women with rheumatoid arthritis. The molecular mechanism of how rheumatoid arthritis and endometriosis may be linked remains unknown. But what is known is that both diseases are inflammatory in nature. It is also thought that autoimmunity, like in the case of rheumatoid arthritis, may…

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