Özge Özkaya, PhD

Özge has a Phd in Molecular Biology and several years experience working as a bench scientists. She has been working in science communication since 2014.

The Severity of Pain Does not Predict Endometriosis or its Stage, Study Confirms

The intensity of pain a woman experiences could predict whether or not she would undergo laparoscopic surgery. However, it could not predict whether she has endometriosis or in case she did, the severity of her disease. This is according to a study published in "The Australian and New Zealand Journal of Obstetrics and Gynaecology". “These findings indicate the need to review current frameworks guiding practice toward surgery for pelvic pain”, wrote Isabelle Conroy and the co-authors of the study. The…

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How Does Endometriosis Affect Patients Quality of Life?

Health-related quality of life is significantly lower in patients with endometriomas or deep infiltrating endometriosis compared to women without the disease. This is according to the results of a recent study in adult Spanish women that was published in the "International Journal of Environmental Research and Public Health".  This is an important finding because it may have important implications in terms of prevention, clinical practice, and intervention. In order to assess health-related quality of life in adult Spanish women with endometriomas…

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Adhesion Barrier Helps After Endometriosis Surgery

An adhesion barrier, named "4DryField® PH" significantly reduced the formation of adhesions following endometriosis surgery, according to a new study by German scientists.  The formation of adhesions following endometriosis surgery is a severe problem that affects 90% of patients. The findings of this study, therefore, provide practical benefits for endometriosis patients undergoing surgery.  In order to evaluate the effectiveness of this particular adhesion barrier in preventing the formation of adhesions following endometriosis surgery, a team of researchers led by Dr.…

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The Surgical Management of Endometriosis of the Ureter and Bladder

Laparoscopic surgery is feasible and safe to manage endometriosis of the ureter and bladder, according to a new study published in the Journal of Minimally Invasive Gynecology. According to the authors of the study, ureteral resection is more strongly associated with laparotomy and more complications compared to other procedures and should be reserved for cases where ureterolysis is not feasible or in case of recurrence. The best surgical management of patients with endometriosis of the ureter and bladder remains controversial. …

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Peritoneal Pockets and Endometriosis

Infertile women with peritoneal pockets had more endometriosis compared to women without pockets according to a study published in the Journal of Obstetrics and Gynaecology Canada. Severe pelvic pain was also associated with the presence of pockets and the presence of endometriosis as well as its severity. These findings are important because they can guide decision-making about whether or not to treat peritoneal pockets in women with infertility and endometriosis. In order to evaluate the prevalence of endometriosis and peritoneal…

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Low-Dose Aspirin as a Potential Treatment for Endometriosis-Related Infertility

Treatment with low-dose aspirin could downregulate progesterone resistance and increase the expression of leukemia inhibitory factor (LIF) during the implantation window, according to a study that used a rat model of endometriosis. This, in turn, could improve endometrial receptivity and increase the pregnancy rate.  These findings are important because they suggest that this approach could also be used to treat infertility in women with endometriosis. It is thought that 30 to 50% of women with endometriosis are infertile or have…

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Genetic Predisposition to Endometriosis

Certain genetic polymorphisms, called SNPs, in the ESR2 and CYP19A1 genes, were more prevalent among patients with endometriosis compared to women without the disease according to a study by researchers in Poland.  A better understanding of the genetic mechanisms underlying the disease, could pave the way to the development of new therapies in the future and improve outcomes in endometriosis.  Previous research has shown that two genes, estrogen receptor 2 (ESR2) and cytochrome P450 family 19 subfamily A member 1 (CYP19A1)…

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Endometriosis Surgery Improves Sex Life

Women who underwent laparoscopic resection surgery to treat their deep infiltrating endometriosis had improved sexual quality of life and health-related quality of life according to a new study published in the Journal of Minimally Invasive Gynecology. These findings are important because they can help guide the right standard of care in the surgical treatment of deep infiltrating endometriosis. In order to investigate the long-term effects of laparoscopic excision surgery to treat deep infiltrating endometriosis on the sexual quality of life and…

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Could There Be a Relationship Between Endometriosis and the "Restless Leg Syndrome"?

Women with endometriosis have a significantly higher prevalence of restless leg syndrome according to a study published in the scientific journal "Frontiers in Endocrinology". This is the first study highlighting such an association between the two conditions. These findings are important because they can pave the way to the discovery of new therapies that could address both conditions and improve patients’ quality of life. Restless legs syndrome is characterized by an uncontrollable urge to move the legs especially in the evening…

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Surgery for the Treatment of Endometriosis of the Diaphragm and Thorax

Diaphragmatic and thoracic endometriosis starts in the abdominal wall of the diaphragm and later invades the thorax, based on findings from a series of patients surgically treated for the disease, reports a study published in the Journal of Gynecology Obstetrics and Human Reproduction.  Therefore, early diagnosis is of great importance, according to Dr. Alexia Wetzel and the co-others of the study who stress that chest pain should be systematically investigated in patients experiencing pelvic endometriosis. To review the current management…

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What Happens to Endometriosis Patients After Endometriosis Surgery?

Although few patients with endometriosis who undergo a hysterectomy need repeat surgery, up to 25% of them need minor surgery. Around 20% of patients who undergo conservative surgery with ovarian preservation require additional endometriosis surgery. Up to one in three patients who had uterine sparing endometriosis surgery later seek infertility assessment.  These results suggest that women with endometriosis should be offered counseling before surgery to inform them about the possibility of their symptoms recurring, the possible need for repeat surgery,…

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Targeting Endometriosis From a Different Angle

Dopamine agonists could help reduce the size of endometriosis lesions and minimize pain, while maintaining ovulation, according to a new study published in the scientific journal Human Reproduction. This constitutes a completely different approach in targeting endometriosis according to Dr. Nuria Pellicer and the co-authors of the study. In the present study, the team of researchers reviewed experimental and clinical data to assess the feasibility of reducing angiogenesis using dopamine agonists to treat endometriosis. Angiogenesis or the formation of new…

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Endometriosis of the Diaphragm, What do the Doctors Know About it?

The median time between the first consultation with a primary care physician and receiving a diagnosis of endometriosis of the diaphragm is two years according to a study by U.K. researchers. In the worse case, it took 23 years for a patient to receive a diagnosis, the study found. The reason for the delay is a lack of awareness among patients and healthcare professionals, according to Rachel Piccus and the co-authors of the study. “ The diagnosis of [diaphragmatic endometriosis]…

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Chronic Opioid Use in Women with Endometriosis

Women with endometriosis are at a higher risk of chronic opioid use compared to those without the disease, according to a new study by researchers in the U.S. This could be due to other diseases that accompany endometriosis.  This finding is important because it could guide clinicians in their choice of pain-relief medication they prescribe patients with endometriosis. In order to evaluate the factors associated with a higher risk of chronic opioid use and the risk of associated complications, the…

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Pain Sensitization and What Should Be Done About it?

Pain sensitization and lumbopelvic impairments are common among women with endometriosis, especially if they have advanced stage disease. This is according to a study by researchers in Spain that was published in the scientific journal "Pain Medicine". The finding underscores the importance of developing rehabilitation interventions targeting pain and lumbopelvic impairments in endometriosis patients. To explore the effect of endometriosis on hypersensitivity to pain and musculoskeletal impairments in the lumbopelvic region, the team of researchers led by Dr. Francisco Artacho-Cordón conducted…

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Perineal Endometriosis, How Soon Does it Return After Surgery?

The higher the body mass index (BMI) of a woman during delivery and within one month after delivery, the quicker the symptoms of perineal endometriosis return. This is according to a recent study that appeared in the World Journal of Clinical Cases. Based on this finding, the authors stress the importance of evaluating the location of endometrial lesions before surgery and recommend immediate surgery following a diagnosis of perineal endometriosis.  Perineal endometriosis is a rare form of endometriosis where hard…

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Selected Blood Inflammatory Biomarkers May Help Identify Endometriosis

Levels of inflammatory biomarkers in the blood differ between women with endometriosis and those without the disease. Levels of some biomarkers also differ according to the stage of endometriosis. This is according to a new study by Polish scientists published in the "International Journal of Molecular Sciences". Based on this finding, the researchers propose a panel of inflammatory biomarkers that could be used to identify women with advanced-stage endometriosis who could qualify for treatment. It is already known that endometriosis…

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Endometriosis and Sexual Satisfaction

Endometriosis affects the ability to have an orgasm during sexual intercourse, according to a study published in The Journal of Sexual Medicine. However, the disease does not have an effect on reaching orgasm via masturbation or sexual activities with a partner that does not involve intercourse. These findings suggest that women living with chronic pelvic pain due to endometriosis could increase their sexual satisfaction by integrating activities in their sex lives that do not involve intercourse. Painful intercourse is one…

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Do Adolescents Know About Endometriosis?

Most secondary school girls have painful periods and many of them don’t know what typical periods are like, according to a study published in the "Journal of Pediatric and Adolescent Gynecology".  The majority of the girls do not have knowledge of endometriosis, although they are familiar with other chronic conditions such as diabetes and epilepsy. This finding is important and suggests that menstrual health education at school is important to improve knowledge about what a typical period is like, how to…

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KEYNOTE: Excision Without Mutilation: It’s Possible! -  Arnaud Wattiez, MD

In his keynote lecture, Dr. Wattiez talks about the pros and cons of endometriosis surgery and the importance of tailoring endometriosis surgery to individual patients.  “Endometriosis is a disease that degrades patient’s wellbeing," Dr. Wattiez says and gives some examples of the disease’s negative impact on patients’ quality of life. According to Wattiez, 84% of women with endometriosis have a decrease in the quality of their work, one in five report being temporarily disabled, and 40% have their career growth…

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