Özge Özkaya, PhD

Özge has a Phd in Molecular Biology and several years experience working as a bench scientists. She has been working in science communication since 2014.

New Insights on Infertility and Low Success Rates of Assisted Reproduction in Women with Endometriosis

The fluid surrounding immature eggs waiting to mature and be fertilized by a sperm to lead to pregnancy is different in women with endometriosis compared to those without, according to a study published in Molecular Biology Reports. This could explain, at least in part, the low success rate of assisted reproductive techniques for couples in which the woman has endometriosis.  The difference is at the level of cytokines, which are signaling molecules that different cells of the immune system use…

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Hysterolaparoscopy Plus Assisted Reproduction Improves Fertility in Women with Endometriosis

Hysteroscopy and laparoscopic surgery is an effective and reliable therapeutic procedure, confirmed a study published in the "Journal of Clinical Medicine". The approach is even more effective when combined with assisted reproductive techniques such as artificial insemination and in vitro fertilization (IVF) performed in a timely manner following surgery.  The combination of the two approaches significantly improves women’s reproductive performance, and enhances their wellbeing and quality of life, the study found. For the study, a team of researchers in Hungary…

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A Routine Pelvic Ultrasound Examination Should Include an Evaluation for Endometriosis

Routine pelvic ultrasound examination should be extended beyond the uterus and ovaries into the posterior and anterior pelvic compartments, according to Australian doctors.  With such examinations, deep infiltrating endometriosis nodules can be searched, say the authors, allowing women to be diagnosed before surgery. This way, a well-prepared team of surgeons can perform a single operation to treat patients. In order to show how the evaluation for endometriosis can be included in a routine pelvic ultrasound examination, Drs. Sophie Piessens and…

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Can Controlled Trials Help Surgeons Decide on Best Way to Treat Endometriosis-Associated Pain?

It may not be realistic to base the decision on the best way to surgically treat pain in a woman with endometriosis on the results of surgical randomized controlled trials. This is according to a study by researchers at the Royal Hospital for Women, and the School of Women's and Children's Health at the University of New South Wales in Sydney, Australia. However, surgeons must be willing to “accept and adopt the evidence when it does demonstrate a particular outcome,"…

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Does Getting Pregnant Really Help When You Have Endometriosis?

Pregnancy has a favorable impact on the volume of deep infiltrating endometriosis lesions according to a study published in the scientific journal "PLoS One". This is the first study that demonstrates such a favorable impact of pregnancy on endometriosis lesion volume. For the study, researchers led by the French researcher Dr. Charles Chapron compared the volume of deep infiltrating endometriosis lesions before and after pregnancy. They did this using magnetic resonance imaging (MRI), an imaging technique that uses a magnetic…

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Endometriosis May Change Women’s Personality, Study Suggests

The personality of women may be altered as a result of endometriosis, according to a study published in the Journal of "Psychosomatic Obstetrics & Gynecology". This finding suggests that a better understanding of the disease is needed in order to provide affected women the best possible care by a multi-disciplinary team that includes psychologists. Endometriosis is a disease that is multidimensional. It has a wide range of symptoms, including chronic pain. In addition, its likely course is full of uncertainties…

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Endometriosis and Women’s Tendency Towards Blood Clotting

Women with ovarian endometriomas have an abnormally increased tendency toward blood clotting, study shows. Researchers think that this is due to the inflammatory nature of endometriosis. So abnormal coagulation parameters could be used to diagnose endometriosis, however, more detailed studies in a larger group of patients are needed in order to confirm the potential diagnostic power of the blood clotting parameter. It was already known that increased coagulation parameters including fibrinogen (a glycoprotein that circulates in the blood and that…

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Endometriosis Surgery and the Chances of Getting Pregnant

Women with deep infiltrating endometriosis who have had two or more failed attempts at assisted reproduction may be referred for surgery according to a study published in the Journal of Minimally Invasive Gynecology. The authors also found that the surgery does not delay conception. This finding can guide informed decision making regarding endometriosis surgery and women’s chances of conceiving. In the study, a team of researchers led by Dr. Horace Roman wanted to assess the probability of women with deep infiltrating…

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Could my Peritoneal Fluid Have a Negative Effect on my Partner’s Sperm?

The peritoneal fluid of women with endometriosis could negatively affect the quality and functionality of sperm, according to a study by Spanish researchers. This could explain infertility linked to the male partners of women with endometriosis. The knowledge could also be used to diagnose infertility linked to the male partner. The peritoneal fluid is the liquid made in the abdominal cavity to lubricate the tissues that line the abdominal wall and pelvic cavity. It is known that endometriosis can change…

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Endometriosis Severity and Complication Risks Following Laparoscopic Surgery

In a research article published in the journal Acta Obstetricia et Gynecologica Scandinavica, researchers at Brigham and Women's Hospital in Boston, Massachusetts suggested that the severity of endometriosis could not be a predictor of the risk of post-operative complications. In a letter to the editor of the same journal, researchers at the University of Sidney say that this could be due to the lack of adequate imaging before the operation. Imaging techniques such as magnetic resonance imaging (MRI) and ultrasound…

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What do Women with Endometriosis Think About the Medical Profession?

Failure of surgical treatment, use of the emergency room, and access to complementary healthcare are factors associated with a negative perception of the medical profession in women with endometriosis.  This is according to a study conducted by researchers in British Columbia and published in the Journal of Obstetrics and Gynaecology Canada. Identifying such factors that influence patients’ perception is important because the knowledge can help develop ways to improve this perception. For the study, researchers led by Dr. Paul J.…

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Does the Severity of Endometriosis Increase the Risk of Complications Following Surgery?

The severity of endometriosis cannot predict the risk of complications after laparoscopy. Instead, the complexity of the surgical procedure itself may increase the risk of complications. This is according to a study published in the journal "Acta Obstetricia et Gynecologica Scandinavica". Identifying factors affecting the risk of complications following surgery in women with endometriosis is important because it can help better plan the surgery as well as counsel patients about the operation. In order to determine whether any patient or procedure…

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Quality of Endometriosis Healthcare: What Do Patients Feel, What Do Doctors Say?

Patients and doctors seem to agree that clinical care for women with endometriosis needs improving. This is according to the results of a study published in the Journal of Psychosomatic Obstetrics & Gynecology.  Endometriosis is a severe condition where chronic pelvic pain can be extremely debilitating. It is therefore of great importance to manage the symptoms of the disease in a successful way to allow women to participate in social and economic activities. A good understanding of patients’ and health…

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How Best to Assess Productivity at Work Among Women with Endometriosis?

The health-related productivity questionnaire (HRPQ) is a valid tool to evaluate patient-reported productivity at work and at home among women with endometriosis found a study by U.S. researchers.  This finding is important because it shows that HRPQ can be used in interventional studies to assess the impact of endometriosis on women’s productivity. A better understanding of this impact can help better manage the burden of the disease on society. It is known that endometriosis negatively impacts health-related quality of life,…

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Factors affecting risk of ovarian endometriosis malignancy

Getting married when older, having had ovarian endometriosis for longer, giving birth in a shorter time, and other complications in the uterus that are benign may all increase the risk of ovarian endometriosis malignancy. This is according to a study by Chinese researchers that was published in the Journal of Obstetrics and Gynecology. According to the study, factors that seem to increase the risk of ovarian endometriosis malignancy to return include endometriosis being in an advanced stage, clear-cell carcinomas (a…

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Could Vitamin D Be Linked to Endometriosis?

There does not seem to be a cause-effect relationship between vitamin D status and endometriosis. In other words, too much or not enough vitamin D does not seem to be associated with endometriosis. This is according to a review of the literature conducted by researchers in Italy. Understanding such a relationship, if it exists, would be important in developing new strategies to treat this debilitating condition. It is known that vitamin D is involved in the function of many organs…

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Study Sheds Light on Physiological Processes Associated with Endometriosis

Sensory nerves play an important role in the development of endometriosis as well as fibrosis, confirms a study by Chinese researchers.  A better understanding of physiological processes associated with the development of endometriosis can help researchers devise new ways to treat the disease. Sensory nerves are nerves that are involved in carrying sensory information such as pain and other sensations from different parts of the body to the brain.  Researchers know that endometriotic lesions are hyper-innervated, i.e. have excessive nervous…

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New Protein for Endometriosis Diagnosis

A protein called TIMP3 (tissue inhibitor of metalloproteinase-3) could be used for the diagnosis and prognosis (likely course) of endometriosis.  The early diagnosis of endometriosis is of paramount importance because it can help to diagnosis and thus initiate the right course of treatment without delay, therefore, preventing the development of complication associated with the disease including infertility. A group of researchers from Greece, led by Dr. Grigorios Grimbizis, analysed the expression pattern of TIMP3 in endometrial lesions and in the…

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How Long Does it Take to Be Diagnosed with Endometriosis?

It takes a median of eight years to reach a diagnosis of endometriosis from when the symptoms of the condition first appear confirmed a new British study. Interestingly, it seems that the earlier the symptoms appear, the later the disease is diagnosed. According to the authors, factors that contribute to a delayed diagnosis include: menstrual cramps in adolescence,  the presence of rectovaginal endometriosis,  the normalization of pain and,  the attitudes of healthcare professionals These findings highlight the importance of educating…

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Disparities in Access to Healthcare in Women with Endometriosis

There are significant differences in the use of medical services and prescriptions between women with endometriosis who have private healthcare and those who don’t. This is according to a study published in the American Journal of Obstetrics and Gynaecology.   This finding is important because it underlines the importance of developing healthcare programs to allow all women with endometriosis to be able to access healthcare services and prescriptions. It is also important because it shows the importance of research on healthcare…

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