Endometriosis-related obstetrical complications and their outcome

Endometriosis-related obstetrical complications and their outcome By Selma Oransay

Borisova et al. from the Department of Gynecology and Obstetrics of Peoples' Friendship University, Moskow, Russia, and her colleagues from the Center of Perinatal and Reproductive Medicine of University Perugia, Italy, recently published a review of the literature data about…

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A Call for Pan-Canadian Collaboration for the Care and Quality of Life of Endometriosis Patients

A Call for Pan-Canadian Collaboration for the Care and Quality of Life of Endometriosis Patients By Timur Seckin

Wahl KJ et al., from Canada, drew attention to the lack of health care for endometriosis patients who are estimated to be 1 million in number in Canada in their recent brief communication report. The delay in the diagnosis, the…

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Racial and ethnic disparities and women health

Racial and ethnic disparities and women health By Selma Oransay

The well documented racial and ethnic disparities in Obstetrics and Gynecology in the US make available to use them as an indicator of implicit bias in giving unequal health and care service to minorities. Dr. Bryant from Massachusetts General Hospital,…

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The effect of endometriosis on the quality of life

The effect of endometriosis on the quality of life By Hale Goksever Celik

Endometriosis, the disease defined as the localization of endometrial glandular and stromal tissue outside the uterine cavity, can be diagnosed in the reproductive-aged women with an incidence of 7-15%. However, endometriosis is observed in women with chronic pelvic pain syndrome…

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Endometriosis surgery and future pregnancy complications

Endometriosis surgery and future pregnancy complications By Selma Oransay

Endometriosis is one of the known diseases for infertility in the reproductive period of women. Several studies revealed that endometriosis itself maybe the reason for some unfavorable obstetric outcomes. Localization, the type of endometriotic lesions, and the stage of endometriosis…

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Diaphragmatic endometriosis

Diaphragmatic endometriosis By Selma Oransay

Diaphragmatic endometriosis is a rare clinical condition that may show signs and symptoms like chest pain, right upper quadrant abdominal pain, shoulder pain, pleuritic pain, hemothorax, pneumothorax, hemoptysis, and thoracic endometriosis syndrome while the major part of the patients is…

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Risk of placenta previa is elevated in endometriotic women who underwent surgery.

Risk of placenta previa is elevated in endometriotic women who underwent surgery. By Selma Oransay

In the last decade concerns raised for surgical operations performed before pregnancies of endometriotic patients due to significantly increased risk of pregnancy complications such as placenta previa, preterm birth, hypertensive disorders of pregnancy, placental abruption, postpartum hemorrhage and small baby…

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Increased obstetrical complications after ART therapy in endometriosis patients.

Increased obstetrical complications after ART therapy in endometriosis patients. By Selma Oransay

To examine the impact of endometriosis and adenomyosis on ART therapy, Harada et al. from the Department of Obstetrics and Gynecology of Tottori University, Japan, planned a prospective cohort study and published their results recently in PLoS One.  The study…

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Nanotechnology as a tool for targeted therapy of endometriosis

Nanotechnology as a tool for targeted therapy of endometriosis By Murat Osman

Endometriosis is a process whereby endometrial cells persistently grow and invade extra-uterine tissue through a primarily estrogen-dependent manner. These ectopic endometrial cells proliferate in sometimes an uncontrolled manner, similar to cancer or inflammatory tissues. To proliferate, cells need cholesterol to…

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Infertility in women with endometriosis

Infertility in women with endometriosis By Hale Goksever Celik

Endometriosis is an estrogen-dependent gynecological disease mostly encountered in reproductive-aged women. The most common presenting complaints are dysmenorrhea, dyspareunia, chronic pelvic pain, and infertility. Despite extensive research, the etiopathogenic mechanism underlying the two has not been fully elucidated. Although human…

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Ovarian stimulation regimes: Concerns on progression or recurrence of endometriosis

 Ovarian stimulation regimes: Concerns on progression or recurrence of endometriosis By Selma Oransay

Somigliana et al., from the University of Milan, Italy, performed a literature review to predict the endometriosis-enhancing effect of ART regimes on infertile women and reported their results in Reproductive Biomedicine Online. Their points of interest were increasing dysmenorrhea, dyspareunia, non-menstrual pain and…

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How Ovarian Endometriomas and DIE affect ART outcomes

How Ovarian Endometriomas and DIE affect ART outcomes By Murat Osman

Previous studies have evaluated the impact of an ovarian endometrioma on ovarian reserve and its impact on the success of assisted reproductive technology (ART) outcomes have controversial results.  ART is a method by which a woman’s own hormones are used…

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Maternal and fetal outcomes in women with endometriosis : A review and meta-analysis

Maternal and fetal outcomes in women with endometriosis : A review and meta-analysis By Selma Oransay

Lalani et al from Dept. of Obstet. and Gynecol. , University of Ottowa, Canada, recently published this systemic review and meta-analysis of observational studies in the Journal of Human Reproduction, aimed to present the difference in the maternal and fetal…

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Non-assisted reproductive technology treatment: Is it effective in infertile patients with advanced endometriosis?

Non-assisted reproductive technology treatment: Is it effective in infertile patients with advanced endometriosis? By Hale Goksever Celik

The marriage and childbearing ages delay due to the life-style changes in developed countries. As a result, advanced age becomes a major concern in infertility treatments which consist of non-ART and ART modalities. Non-ART treatments include mild ovarian stimulation together…

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Laparoscopic surgery of endometriosis through three compartments

Laparoscopic surgery of endometriosis through three compartments By Selma Oransay

This case study which is published in the J. of Minimally İnvasive Gynecology is the video demonstration of Collin et al who performed the laparoscopic operation of their patient in Gynecologic Surgery Department of Strasburg Hospital University, France. 37 years old…

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Toxic Pelvic Cavity and Infertility

Toxic Pelvic Cavity and Infertility By Murat Osman

Endometriosis is a disease defined by the presence of endometrial tissue outside of the uterine cavity and has an incidence of approximately 10% in women of reproductive age. Thus, it is an important consideration in chronic pelvic pain and infertility…

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The vaginal delivery rate of singleton term pregnancies still remains the same after total deep infiltrating endometrosis excisions

The vaginal delivery rate of singleton term pregnancies still remains the same after total deep infiltrating endometrosis excisions By Selma Oransay

This recently published report in the Journal of Fertility Sterility is planned as a  matched case-control study, by Nirgianakanis et al. from the University of Bern, Switzerland. Authors claimed their study is the first because previous studies on pregnancy outcome after laparoscopic…

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Health-related quality of life in women with Endometriosis and Rheumatoid Arthritis

Health-related quality of life in women with Endometriosis and Rheumatoid Arthritis By Murat Osman

Endometriosis is a chronic inflammatory disease that is defined by the presence of ectopic endometrial tissue outside of the uterus. Unfortunately, endometriosis continues to be a leading cause of chronic pelvic pain and long-term morbidity in women of reproductive age.…

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Detecting endometriosis using peripheral blood

Detecting endometriosis using peripheral blood By Yu Yu

Laparoscopic visualization of endometriotic lesions with histological confirmation is the gold standard for the diagnosis of endometriosis. However, this diagnostic procedure, due to the need for laparoscopy and variability of disease/symptoms, can have a major delay up to 8-10 years…

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How Artificial Intelligence Can Improve Our Understanding of the Genes Associated with Endometriosis.

How Artificial Intelligence Can Improve Our Understanding of the Genes Associated with Endometriosis. By Dr. Youngran Park

Endometriosis is a disease characterized by the development of endometrial tissue outside the uterus. A number of studies have shown that endometriosis could have a genetic basis and numerous genes have been studied and proposed to help explain its pathogenesis.…

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Therapeutic strategies involving uterine stem cells in reproductive medicine

Therapeutic strategies involving uterine stem cells in reproductive medicine By Murat Osman

Stem cells are undifferentiated cells that often serve to regenerate tissue in states of injury or apoptosis. The endometrium has progenitor cells that replace tissue lost after each menstrual cycle. It has been postulated that excessive stem cell recruitment to…

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Extending the Female Fertility Clock

Extending the Female Fertility Clock By Kasthuri Nair

Varela, Sanchez-de-Puerta, and Garcia-Velasco are a group of scientists from various institutions in Spain and they recently published a review article titled “Fertility, IVF and reproductive genetics” in Current Opinion in Obstetrics and Gynecology. In this publication, the authors discussed…

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Reproductive delay and social egg freezing

Reproductive delay and social egg freezing By Yu Yu

The data collected from Office for National Statistics in England and Wales has suggested a major shift in the timing of motherhood. In the mid-1970s, the average age of motherhood was 26.4 years of age to, while in 2016, it…

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Endometriosis can Adversely Affect Oocyte Quality

Endometriosis can Adversely Affect Oocyte Quality By Kasthuri Nair

Kasapoglu et al. recently published a study in Gynecological Endocrinology titled “Detrimental effects of endometriosis on oocyte morphology in intracytoplasmic sperm injection cycles: a retrospective cohort study.” In this paper, they compared the oocytes recovered from women who have endometriosis…

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Swimming Against the Stream: Is Surgery Worthwhile in Women with Deep Infiltrating Endometriosis and Pregnancy Intention?

Swimming Against the Stream: Is Surgery Worthwhile in Women with Deep Infiltrating Endometriosis and Pregnancy Intention? By Murat Osman

Management of Deeply Infiltrating Endometriosis (DIE) is further complicated by the implications of affected patients who plan to become or are pregnant. Optimal management in this situation is not standardized due to a lack of randomized trials comparing primary surgery…

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Breast Feeding Can Reduce the Risk of Endometriosis

Breast Feeding Can Reduce the Risk of Endometriosis By Kasthuri Nair

In their publication titled “History of breast feeding and risk of incident endometriosis: prospective cohort study,” Farland et al. examine the benefits of breast feeding. The authors initially hypothesize that the length of lactation in women that have been pregnant…

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Updates in the Field of Endometriosis: Fertility

Updates in the Field of Endometriosis: Fertility By Kasthuri Nair

Infertility can be a significant problem for many women who are suffering from endometriosis. In their chapter titled “Endometriosis and Fertility,” Evans and Decherney discuss the role of endometriosis in infertility and examine the usefulness of various fertility treatments. The…

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Updates in the Field of Endometriosis: Fertility Preservation

Updates in the Field of Endometriosis: Fertility Preservation By Kasthuri Nair

“Endometriosis and Fertility” is a chapter dedicated to examining the role of endometriosis and endometriomas in decreasing fertility. In other words, the authors of this chapter discuss the relationship between endometriomas, surgeries, and infertility. Barnett, Banks and Decherney also deliberate…

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First-line surgery followed by ART versus ART alone among women with colon-involving endometriosis.

First-line surgery followed by ART versus ART alone among women with colon-involving endometriosis. By Murat Osman

Endometriosis, a disease characterized by the presence of endometrial tissue outside the uterus, may cause pelvic and gynecologic complications that affect fertility in women of reproductive age. Several forms of endometriosis have been observed that are characterized by the varying…

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Factors that Impact IVF-ICSI Outcomes of live birth

Factors that Impact IVF-ICSI Outcomes of live birth By Kasthuri Nair

Endometriosis affects women in their reproductive years, which often makes it difficult for women with this disease to reproduce. A paper published in the Journal of Assisted Reproduction and Genetics by Roux et al. from Marseille, France, addressed this issue…

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The Involvement of the Blood Clotting System in Endometriosis

The Involvement of the Blood Clotting System in Endometriosis By Özge Özkaya

The blood clotting system might be over-active in women with endometriosis, found a study published in the scientific journal Reproductive Sciences.  Although the authors stated that there is not enough evidence to suggest that over-coagulation may be directly causing endometriosis…

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Combination Therapy Proves More Efficient in the Treatment of Endometriosis

Combination Therapy Proves More Efficient in the Treatment of Endometriosis By Kasthuri Nair

In their recent paper in British Journal of Pharmacology, entitled “Combination therapy with telmisartan and parecoxib induces regression of endometriotic lesions,” Nenicu et al. illustrate the increased effectiveness of telmisartan used along with a cyclooxygenase-2 (COX-2) inhibitor (a non-steroidal anti-inflammatory…

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Can a cure be developed for endometriosis?

Can a cure be developed for endometriosis? By Asli Bahadirli Talbott

The Lancet correspondence highlights that regardless of the importance of endometriosis; its full socioeconomic impact is underestimated and endometriosis research is considerably underfunded. The Endometriosis Priority Setting Partnership (PSP) which includes women with endometriosis, their supporters, health-care practitioners, endometriosis researchers, and representatives from…

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Metabolomic profiling and biochemical evaluation of the follicular fluid of endometriosis patients.

Metabolomic profiling and biochemical evaluation of the follicular fluid of endometriosis patients. By Yu Yu

Metabolites are the intermediates and products of metabolism from our body. Increasingly the study of metabolite content in biological systems can be used to derive useful information to identify disease-related markers, such as the use of glucose in the blood…

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