Devilish triad: Endometriosis-irritable bowel syndrome and eating disorders

Devilish triad: Endometriosis-irritable bowel syndrome and eating disorders By Bahar Yuksel

Most women with endometriosis report digestive symptoms. But it is not well-defined whether those are related to endometriosis itself or a secondary syndrome may be the cause. Irritable bowel syndrome, eating disorders, and anxiety are very commonly diagnosed diseases among women…

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Would it be possible to diagnose endometriosis from a vaginal swab?

Would it be possible to diagnose endometriosis from a vaginal swab? By Nasuhi Engin Aydin

Ectopic endometrial tissues with new vessel formations in an inflammatory background have a component of mast cell-derived exosomal tRF-Leu-AAG-001 promoting inflammation and angiogenesis. This information is according to the paper published in a recent issue of the journal “BMC Women’s Health”,…

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Postoperative outcomes of deep intestinal endometriosis surgery.

 Postoperative outcomes of deep intestinal endometriosis surgery. By Selma Oransay

Invasion of endometriotic lesions to the bowels' mucosal and/or muscular levels is called intestinal deep endometriosis. These lesions are most frequently found in the rectosigmoid colon, followed by the rectum, ileum,  appendix, and caecum. The optimal surgical approach to intestinal deep…

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Endometriosis in transmasculine people

Endometriosis in transmasculine people By Eylül GÜN

“Transmasculine” refers to people who were assigned female at birth but later identify themselves with masculinity. If they choose to transition to the male gender, they are then prescribed long-term testosterone and some may want to undergo a hysterectomy as…

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Thoracic endometriosis: the most frequent endometriosis involvement outside abdominopelvic cavity

Thoracic endometriosis: the most frequent endometriosis involvement outside abdominopelvic cavity By Nasuhi Engin Aydin

Six to ten percent of reproductive-age women are affected by endometriosis, and about 12% are estimated to be outside the abdominopelvic cavity - the most frequent location being the thorax. Endometriosis within the pulmonary parenchyma or on the diaphragm and…

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Which surgical technique is best for rectal endometriosis?

Which surgical technique is best for rectal endometriosis? By Eylül GÜN

One of the common sites for deep endometriosis is the intestines, with a rate of 3-37%. Intestinal endometriosis constitutes a serious cause of gastrointestinal symptoms, pain, and the alteration of the quality of life, with the rectum and sigmoid colon being…

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Does Surgery Improve the Digestive Symptoms of Endometriosis?

Does Surgery Improve the Digestive Symptoms of Endometriosis? By Özge Özkaya

Women with deep infiltrating endometriosis involving the bowels have the most significant improvement in gastrointestinal symptoms following surgery. This is according to the findings of a comparative retrospective study in almost 1,500 women.  “Women with severe bowel symptoms and deep…

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Non-pharmacological self-care: dietary modifications in women with endometriosis.

Non-pharmacological self-care: dietary modifications in women with endometriosis. By Selma Oransay

The academic interest on the role of diet in endometriosis has grown due to its possible relation with inflammation, estrogenic activity, and menstrual cycles. Multiple dietary strategies and prescriptions are being used to deal with the pelvic pain and gastrointestinal…

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Endometriosis from the "EVOLUTIONARY" point of view

Endometriosis from the By Nasuhi Engin Aydin

Natalie Dinsdale and associates from the Canadian Simon Fraser University Department of Biological Sciences published a critical review titled “ The evolutionary biology of endometriosis” in a recent issue of the journal “Evolution, medicine and public health”. This review focuses…

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Endometriosis in intestine! Segmental resection or linear nodulectomy?

Endometriosis in intestine! Segmental resection or linear nodulectomy? By Bahar Yuksel

Intestinal involvement of endometriosis is common, and the incidence was defined between 45-56%. Previous studies investigating the role of surgery in the management of intestinal endometriosis reported improvement of life quality in up to 95% of cases following surgery. However,…

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Postoperative long-term estro-progestin therapy for endometrioma

Postoperative long-term estro-progestin therapy for endometrioma By Selma Oransay

After the removal of ovarian endometriomas, the major concern is the high recurrence rate of symptoms and endometriotic cysts. The estimated recurrence rate of endometriomas is up to 50% at 5 years after surgery. To prevent the recurrence, postoperatively long-term…

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Testosterone levels effect embryo implantation rates in patients with endometriosis

Testosterone levels effect embryo implantation rates in patients with endometriosis By Bahar Yuksel

Endometriosis is associated with infertility either causing poor oocyte and embryo qualities or poor endometrial receptivity. The effect of androgen levels on IVF outcomes has been described earlier, but the present study conducted by Ling Huang et assocates is the…

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Fertilization rate and pregnancy outcome in IVF cycles of endometriosis.

Fertilization rate and pregnancy outcome in IVF cycles of endometriosis. By Selma Oransay

Endometriosis affects the pelvic cavity, uterus, ovaries and causes impaired fertility as a result. The chronic inflammatory nature of this disease negatively impacts the oocyte quality, maturation, and fertilization. Obviously, fewer oocytes can be harvested in the IVF cycles of…

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Live Birth Rate in Women Who Underwent Fresh Embryo Transfer Using Freshly Retrieved Donor Oocytes

Live Birth Rate in Women Who Underwent Fresh Embryo Transfer Using Freshly Retrieved Donor Oocytes By Hale Goksever Celik

One of the important clinical findings in women with endometriosis is reproductive problems. Infertility can be encountered in up to 50% of women with endometriosis and up to 50% of women with infertility can be diagnosed with endometriosis. Several pathophysiologic…

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Comparison of diagnostic accuracy of imaging modalities for the deep infiltrating endometriosis

Comparison of diagnostic accuracy of imaging modalities for the deep infiltrating endometriosis By Selma Oransay

The treatment of deeply infiltrated endometriosis (DIE) is usually personalized and the potential success for the available therapeutical options is dependent on early and accurate diagnosis. Laparoscopy is the gold standard for the diagnosis of DIE. Other non-invasive diagnostic methods…

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Time for reassessment : Laparoscopic surgery and bowel endometriosis

Time for reassessment : Laparoscopic surgery and bowel endometriosis By Nasuhi Engin Aydin

Ferrero and associates from medical centers of Verona and Genoa, Italy, made a comprehensive review covering all aspects of the surgical approach to bowel endometriosis, published their results in "Best Practice & Research Clinical Obstetrics and Gynaecology". Bowel endometriosis is the…

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Colorectal Deep Endometriosis Resection and Potential Complications

Colorectal Deep Endometriosis Resection and Potential Complications By Murat Osman

A severe clinical form of endometriosis, deeply infiltrating endometriosis (DIE) is characterized by more aggressive endometriotic lesions commonly involving deeper pelvic or gastrointestinal organs. It causes significant quality of life impairment and morbidity and is increasingly associated with infertility. When…

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Endometriotic mesenchymal stem cells may promote endometriosis

Endometriotic mesenchymal stem cells may promote endometriosis By Yu Yu

The cause of endometriosis is still debatable. Many researchers have accepted that retrograde menstruation, where the endometrial fragments released during menstruation attach and colonize the ectopic locations, is the most plausible reason. However, the numbers just do not add up.…

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Voiding Dysfunction after Colorectal Surgery for Endometriosis

Voiding Dysfunction after Colorectal Surgery for Endometriosis By Timur Seckin

Postoperative voiding dysfunction is a less frequent complication of rectal shaving than that of discoid excision or segmental resection in patients undergoing colorectal surgery for endometriosis, regardless of its definition. This is according to a meta-analysis conducted by researchers from…

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Endometriosis Impacts Transgender Adolescents

Endometriosis Impacts Transgender Adolescents By Irem Onur

Shim J.Y. et al, from Boston, Massachusetts retrospectively searched the electronic medical records of transmasculine patients younger than 26 years old who were diagnosed with dysmenorrhea and treated at Boston Children’s Hospital, between January 1, 2000, and March 1, 2020.…

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Imaging of gastrointestinal endometriosis

Imaging of gastrointestinal endometriosis By Murat Osman

Endometriosis is a disease characterized by the ectopic implantation of endometrial tissue to surrounding pelvic and extra-pelvic structures. One frequent site of involvement is the gastrointestinal(GI) tract, which occurs especially among women with deep infiltrating endometriosis. Most cases of GI-involving…

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Fertility preservation protocols in women with endometriosis

Fertility preservation protocols in women with endometriosis By Hale Goksever Celik

Infertility is one of the major symptoms in women with endometriosis. Childbearing at a delayed age is preferred by the majority of women recently who consult for the demand for fertility preservation procedures. There are several techniques for fertility preservation…

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Cycle-related gastrointestinal complaints in reproductive age young women

Cycle-related gastrointestinal complaints in reproductive age young women By Timur Seckin

An analysis of 1-year data on 266 patients who presented to the Clinic and Polyclinic for Gynecology and Reproductive Medicine at Jena University Hospital to undergo surgery for endometriosis and its symptoms was performed by Nicolaous K. et al., a…

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Endometriosis May Change Women’s Personality, Study Suggests

Endometriosis May Change Women’s Personality, Study Suggests By Özge Özkaya

The personality of women may be altered as a result of endometriosis, according to a study published in the Journal of "Psychosomatic Obstetrics & Gynecology". This finding suggests that a better understanding of the disease is needed in order to…

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Endometriosis and ovarian reserve

Endometriosis and ovarian reserve By Hale Goksever Celik

Endometriosis is most frequently encountered in reproductive-aged women. Its prevalence is 10-15% in the general population of this age. However, endometriosis is diagnosed more frequently in infertile women with a prevalence of 25-40%. Although the exact mechanism explaining the association between…

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Hemorrhagic Ascites, Belly-Blood: The cause may be endometriosis!

Hemorrhagic Ascites, Belly-Blood: The cause may be endometriosis! By Timur Seckin

A paper on the presentation of hemorrhagic ascites in endometriosis patients, written by Bernard et al. from the United States and China, was published in the journal Fertility and Sterility. From 1978 to 2016, the authors found only 37 articles, which describe 42…

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CD4, CD8 T lymphocytes gain importance in endometriosis

CD4, CD8 T lymphocytes gain importance in endometriosis By Nasuhi Engin Aydin

Immune dysregulation is important in the development of endometriosis where the role of various lymphocyte subpopulations has been investigated up till now. Caihua Li and associates from Anhui Medical University, China, made a unique observation regarding CD4 and CD8 T…

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Endometriosis and Insulin dependent Diabetes Mellitus

Endometriosis and Insulin dependent Diabetes Mellitus By Nasuhi Engin Aydin

Simmen and associates from the University of Arkansas for Medical Sciences, Alabama, published a review article about the co-existence of type 1 diabetes mellitus (T1DM)  and endometriosis, in the recent issue of the "Journal of Endocrinology". Insulin-dependent diabetes or T1DM…

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How to Classify Endometriosis for a better and effective evaluation

How to Classify Endometriosis for a better and effective evaluation By Selma Oransay

Endometriosis affects 10% of women in their reproductive period and causes infertility around 40% of women who have the disease. Peritoneal fluid may be one of the factors to facilitate the spread of endometriosis to ovaries, peritoneum and other deep…

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Seven Hormonal Biomarkers for Diagnosing Endometriosis

Seven Hormonal Biomarkers for Diagnosing Endometriosis By Dr. Youngran Park

Endometriosis is an inflammatory condition characterized by implantation and invasive growth of endometrial tissue outside the uterine cavity. Although it is benign, endometriosis has cancer-like features, a mutation profile similar to that of ovarian cancer, and increased ovarian cancer risk.…

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The postoperative functional outcomes of deep infiltrating endometriosis

The postoperative functional outcomes of deep infiltrating endometriosis By Hale Goksever Celik

Rectosigmoid endometriosis is defined as the infiltration of the bowel wall with the endometrial-like glands and stroma, reaching at least the muscular layer. The most commonly involved sites are the rectum and sigmoid colon. For the management of deep infiltrating…

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Antimullerian Hormone, endometrioma and ovarian reserve

Antimullerian Hormone, endometrioma and ovarian reserve By Selma Oransay

Younis et al. from Baruch-Padeh Medical Center, Poriya, Israel, designed a review study on ovarian reserve alterations before and after endometrioma surgery that recently documented in "Human Reproduction Update". The authors examined the electronic databases of articles published between January…

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Preoperative factors to predict unresponsiveness in women undergoing endometriosis surgery

Preoperative factors to predict unresponsiveness in women undergoing endometriosis surgery By Hale Goksever Celik

Endometriosis is defined as the localization of endometrial glandular and stromal cells outside the uterine cavity. Despite extensive research, the optimal management of endometriosis still remains unclear. Several treatment options include analgesic medication, hormonal treatments, and surgical intervention. There is…

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Bowel endometriosis: What you need to know

Bowel endometriosis: What you need to know By Demet Candaş Green

When the endometrial tissue infiltrates the intestinal walls and reaches inside the intestines, this condition is called "bowel endometriosis". It is estimated that between 3.8% and 37% of women with endometriosis are affected by bowel endometriosis. The endometriosis lesions infiltrating…

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Vaginal Sexual Intercourse during Menstruation

Vaginal Sexual Intercourse during Menstruation By Irem Onur

Mazokopakis and Samonis from Greece examined and discussed the vaginal sexual intercourse during menstruation from a biblical as well as a modern medical point of view in their paper published in MAEDICA – a Journal of Clinical Medicine in September 2018.…

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Development of Less Invasive Diagnostic Tests for Endometriosis Through Proteomics

Development of Less Invasive Diagnostic Tests for Endometriosis Through Proteomics By Murat Osman

Proteomics is a field which utilizes various methods to carry out large-scale studies of proteins. Due to the inherent nature of the field, proteomics focuses on the identification, localization, and functional analysis of the protein make-up of a given type…

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Extragenital endometriosis and ultrasound

Extragenital endometriosis and ultrasound By Irem Onur

Contrast-enhanced ultrasound (CEUS) is a non-invasive imaging method with no exposure to radiation. There are a few reports on the use of CEUS in the assessment of endometriosis in the literature. Dong et al. reported 3 histopathologically proven cases of…

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An overlooked symptom of endometriosis: Fatigue

An overlooked symptom of endometriosis: Fatigue By Timur Seckin

A majority of endometriosis patients experience fatigue. This is according to a multicenter study conducted by a group of researchers from Switzerland, Germany, and Austria. Fatigue, and feeling spoonie, may be a symptom of endometriosis affecting the daily activities and…

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Factors Associated with Endometriosis Risk

Factors Associated with Endometriosis Risk By Özge Özkaya

Socio-economic factors, lifestyle habits, and other physical and mental illnesses may be linked to endometriosis according to a new observational study published in the European Journal Of Obstetrics Gynecology And Reproductive Biology.  Endometriosis is a debilitating condition affecting as many…

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Maternal and fetal outcomes in women with endometriosis : A review and meta-analysis

Maternal and fetal outcomes in women with endometriosis : A review and meta-analysis By Selma Oransay

Lalani et al from Dept. of Obstet. and Gynecol. , University of Ottowa, Canada, recently published this systemic review and meta-analysis of observational studies in the Journal of Human Reproduction, aimed to present the difference in the maternal and fetal…

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PROPOFOL: a new combat for endometriosis?

PROPOFOL: a new combat for endometriosis? By Selma Oransay

Feng et al, from the Department of  Gynecology Weifang Medical University Hospital, Shandong, China, recently published their prospective experimental research in the journal Experimental and Therapeutic Medicine. Propofol, a rapid and short-term anesthetic substance, recently has been shown to prevent cancer through inhibiting…

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Cosmetics and some household products could be responsible for worsening endometriosis.

Cosmetics and some household products could be responsible for worsening endometriosis. By Selma Oransay

A controlled clinical study recently published in the Journal of Human Reproductive Sciences,  composed by Nazir et al. from the University of Health Sciences, Lahore, Pakistan. The study compared the blood diethyl hexyl phthalate (DEHP) levels of fifty infertile women laparoscopically diagnosed…

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Catching Endometriosis Early

Catching Endometriosis Early By Kasthuri Nair

Li et al., a group primarily from Sun Yat-sen University in the People’s Republic of China, recently published an article titled “Endometrium metabolomic profiling reveals potential biomarkers for diagnosis of endometriosis at minimal-mild stages” in Reproductive Biology and Endocrinology. The…

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Difficulties Associated with Diagnosing Ascites and Encapsulating Peritonitis in Endometriosis

Difficulties Associated with Diagnosing Ascites and Encapsulating Peritonitis in Endometriosis By Kasthuri Nair

De Magalhães et al. recently published a paper titled “Ascites and Encapsulating Peritonitis in Endometriosis: a Systematic Review with a Case Report” in Revista Brasileira de Ginecologia e Obstetrícia. The team from the Universidade Federal do Ceará and the Universidade…

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Therapeutic strategies involving uterine stem cells in reproductive medicine

Therapeutic strategies involving uterine stem cells in reproductive medicine By Murat Osman

Stem cells are undifferentiated cells that often serve to regenerate tissue in states of injury or apoptosis. The endometrium has progenitor cells that replace tissue lost after each menstrual cycle. It has been postulated that excessive stem cell recruitment to…

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Thoracic Endometriosis Syndrome : A case report describing endometriosis involvement of the lung

Thoracic Endometriosis Syndrome : A case report describing endometriosis involvement of the lung By Murat Osman

Leonardo-Pinto and authors from the Universidade Estadual de Campinas, Brazil, have recently published a case report titled, "Hemoptysis and Endometriosis: An Unusual Association - Case Report and Review of the Literature" in the Journal, Revista Brasileira De Ginecologia E Obstetricia describing a…

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Intestinal Endometriosis and Colorectal Cancer versus T4 Colorectal Cancer

Intestinal Endometriosis and Colorectal Cancer versus T4 Colorectal Cancer By Kasthuri Nair

Ishii et al. recently published a paper titled “Intestinal endometriosis combined with colorectal cancer: a case series” in the Journal of Medical Case Reports. This case report follows 7 Japanese women who have intestinal endometriosis and colorectal cancer. These women…

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MRI Best at Detecting Intestinal Deep Infiltrating Endometriosis

MRI Best at Detecting Intestinal Deep Infiltrating Endometriosis By Özge Özkaya

Magnetic resonance imaging (MRI) seems to be a better method in identifying deep infiltrating endometriosis in the intestine compared to two-dimensional ultrasonography (2DUS), found a study by researchers in Italy and Spain. However, this does not seem to be the…

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Gestational diabetes risk in women with endometriosis

Gestational diabetes risk in women with endometriosis By Demet Candaş Green

Gestational diabetes (GD) is a common complication in pregnancy with several negative consequences for both mother and baby.  The risk of developing GD increases with maternal age and body mass index (BMI). Women with endometriosis conceive later than fertile women,…

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EFA Medical Conference 2017: "Cells Are the New Cure" Presentation by Dr. Max Gomez

EFA Medical Conference 2017: By Kasthuri Nair

Dr. Max Gomez is an award-winning broadcast journalist, CBS News Medical Correspondent, and a presenter at the EFA 2017 Medical Conference. Dr. Gomez’s presentation was titled “Cells Are the New Cure: The Cutting-Edge Medical Breakthroughs That Are Transforming Our Health.”…

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Characteristics and location of extrapelvic endometriosis

Characteristics and location of extrapelvic endometriosis By Demet Candaş Green

The authors of this study reviewed the medical records of 1000 women with endometriosis from two geographical areas, New Haven, US and Crete, Greece over a 20-year period with a goal of identifying the presence and location of extrapelvic endometriosis…

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Best Time for IVF Between 7 and 25 Months Post Surgery Study Suggests

Best Time for IVF Between 7 and 25 Months Post Surgery Study Suggests By Özge Özkaya

The more severe endometriosis is, the lower the success rate of IVF, according to a new study published in the Journal of Minimally Invasive Gynecology. However, the presence of endometriosis as such does not seem to affect the outcome of…

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