Somatic mutations in iatrogenic endometriosis.

Somatic mutations in iatrogenic endometriosis. By Selma Oransay

Lac and al., from the Department of Molecular Oncology in BC Cancer Research Center, Vancouver, Canada, planned a retrospective and multinational research to investigate the prevalence of somatic cancer-driver mutations in incisional endometriosis and recently published in the "Journal of Human Reproduction". Their…

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Further Results From the FEELING Study Published

Further Results From the FEELING Study Published By Özge Özkaya

Some women are more likely to develop deep infiltrating endometriosis according to the further analysis of the results of the FEELING study. These are women who: are married, are older,  have siblings,  have had a prior pregnancy,  or for whom…

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The diagnosis and management of endometriosis in Korea

The diagnosis and management of endometriosis in Korea By Selma Oransay

The Korean Society of Endometriosis has scrutinized the present published literature of endometriosis in the domestic and international platform to provide new guidelines and the clinical management of the disease. The study was recently published in the journal "Obstetrics and Gynecology…

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Can MRI be used to detect anterior pelvic endometriotic lesions?

Can MRI be used to detect anterior pelvic endometriotic lesions? By Hale Goksever Celik

Deep infiltrating endometriosis is the most severe manifestation of endometriosis. It is defined as the infiltration of ectopic endometrial tissue under the peritoneum, pelvic structures, and the organ walls such as the uterosacral ligaments, colon, vagina, bladder, ureter, rectovaginal septum,…

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Does deep infiltrating endometriosis affect sexual activity?

Does deep infiltrating endometriosis affect sexual activity? By Dr. Youngran Park

Endometriosis is one of the most common gynecological diseases in women of reproductive age, and pelvic pain and infertility are the most frequent complications. There are three different type of endometriosis lesions; superficial lesions, deep lesions, and ovarian cysts. In…

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Parametrial endometriosis: A harder form of endometriosis

Parametrial endometriosis: A harder form of endometriosis By Hale Goksever Celik

Deep infiltrating endometriosis is the most severe manifestation of endometriosis, affecting 20% of all patients with endometriosis. It is defined as the infiltration of ectopic endometrial tissue under the peritoneum, pelvic structures, and the organ walls such as the uterosacral…

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Will I Have Complications After Endometriosis Surgery?

Will I Have Complications After Endometriosis Surgery? By Özge Özkaya

The rate of complications after surgery to treat deep infiltrating endometriosis is low, confirmed a study by researchers in Germany. It is important to know whether major or minor complications following surgery are likely to develop and what the outcome…

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Laparoscopic surgery of endometriosis through three compartments

Laparoscopic surgery of endometriosis through three compartments By Selma Oransay

This case study which is published in the J. of Minimally İnvasive Gynecology is the video demonstration of Collin et al who performed the laparoscopic operation of their patient in Gynecologic Surgery Department of Strasburg Hospital University, France. 37 years old…

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IVF Is the Best Option to Become Pregnant for Women with Severe Endometriosis, or Is It Not?

IVF Is the Best Option to Become Pregnant for Women with Severe Endometriosis, or Is It Not? By Özge Özkaya

Treating rectal endometriosis with surgery seems to increase the chance of a woman conceiving, with most pregnancies occurring naturally. This is according to a study published in the medical journal Human Reproduction.  The optimal treatment for women with severe endometriosis…

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Endometrioma and endometriosis

Endometrioma and endometriosis By Irem Onur

Exacoustos C. et al. published an article titled “The isolated ovarian endometrioma: a history between myth and reality” in the Journal of Minimally Invasive Gynecology in 2018. They aimed to examine the association between ovarian endometriomas detectable at the transvaginal ultrasound…

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How to evaluate ureteral endometriosis : A review of the literature

How to evaluate ureteral endometriosis :  A review of the  literature By Selma Oransay

In this recently published review of the literature, Barra et al. from Genova, Italy intend to provide a useful tool to guide physicians in the management of deep infiltrating endometriosis. Authors elected 67 abstracts from Pubmed and Medline in accordance with PRISMA…

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Fluorescence Guided Surgery: a New Technique to Treat Deep Infiltrating Endometriosis

Fluorescence Guided Surgery: a New Technique to Treat Deep Infiltrating Endometriosis By Özge Özkaya

Fluorescence-guided surgery could help differentiate recto-vaginal deep infiltrating endometriosis nodules (RVDIEN) from healthy rectal tissue and remove them successfully without perforating the rectum, according to a study published in the scientific journal Surgical Innovation.  The method could offer a better,…

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Deep Infiltrating Endometriosis Impairs Sexual Function

Deep Infiltrating Endometriosis Impairs Sexual Function By Kasthuri Nair

Lima et al., a group of scientists from Hospital do Servidor Público Estadual in Brazil, recently published an article entitled “Female Sexual Function in Women with Suspected Deep Infiltrating Endometriosis” in Revista Brasileira De Ginecologia E Obstetricia. The paper analyzed…

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Recurrence of Deep Infiltrating Endometriosis

Recurrence of Deep Infiltrating Endometriosis By Yu Yu

There are mainly three types of endometriotic lesions. These are ovarian endometriosis, superficial peritoneal endometriosis, and deep infiltrating endometriosis (DIE). The latter is often described as a lesion with greater than 5 mm invasion of the peritoneal surface. DIE lesions…

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MRI Best at Detecting Intestinal Deep Infiltrating Endometriosis

MRI Best at Detecting Intestinal Deep Infiltrating Endometriosis By Özge Özkaya

Magnetic resonance imaging (MRI) seems to be a better method in identifying deep infiltrating endometriosis in the intestine compared to two-dimensional ultrasonography (2DUS), found a study by researchers in Italy and Spain. However, this does not seem to be the…

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Fetal Membranes Abnormalities in Pregnant Women with DIE

Fetal Membranes Abnormalities in Pregnant Women with DIE By Kasthuri Nair

Marcellin, Méhats, and Gogusev formulated a study where they analyzed alterations in the fetal membranes (FM) of women suffering from severe endometriosis. Their paper titled “Histopathological Alterations in Fetal Membranes of Women With Endometriosis” was recently published in the Reproductive…

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Women with Deep Infiltrating Endometriosis Have a Higher Risk of Appendix Involvement

Women with Deep Infiltrating Endometriosis Have a Higher Risk of Appendix Involvement By Özge Özkaya

Women with deep-infiltrating endometriosis, a form of endometriosis that invades the abdominal and pelvic cavity, have an increased risk of developing endometriosis of the appendix. It is therefore important to check women with deep infiltrating endometriosis for appendix involvement during…

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Ovarian Endometriomas vs Deep Infiltrating Endometriosis

Ovarian Endometriomas vs Deep Infiltrating Endometriosis By Yu Yu

Ovarian endometrioma (OMA) and deep infiltrating endometriosis (DIE) have been described as two disease entities, although they are both characterized by endometrial tissue located outside the uterus. As OMA and DIE look different histologically, it is puzzling what cause their…

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Bowel Involvement in Deep Infiltrating Endometriosis

Bowel Involvement in Deep Infiltrating Endometriosis By Özge Özkaya

Cleansing the colon before an ultrasound makes it easier to detect rectal nodules of deep infiltrating endometriosis, found a study published in the Journal of Minimally Invasive Gynecology.  Cleansing the colon before a surgery is called bowel preparation and is…

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Deep Infiltrating Endometriosis, Surgery and Fertility

 Deep Infiltrating Endometriosis, Surgery and Fertility By Kasthuri Nair

Carneiro, Costa, and Ávila recently published an article in a scientific journal named Reproduction, titled “To operate or not to operate on women with deep infiltrating endometriosis (DIE) before in vitro fertilization (IVF),” that explored the relationship between DIE and infertility.…

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A potential indicator of invasive endometriosis. 

A potential indicator of invasive endometriosis.  By Asli Bahadirli Talbott

Furuya & Masuda et al., in their recent article that will be published in Acta Obstet Gynecol Scand, report that the protein encoded by ZEB1 gene (Zinc finger E-box-Binding homeobox) is a potential indicator of invasive endometriosis.  ZEB1 is a transcription factor that has been implicated…

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Unexpected "cancer-related" mutations in "non-cancerous" endometriosis: Do they predict aggressiveness?

Unexpected By Laura Ardighieri

A study supported by Endometriosis Foundation of America, reported by scientists from Johns Hopkins Medicine (Baltimore, USA) and the University of British Columbia (Vancouver, Canada) have identified the molecular alterations of deep infiltrating endometriosis trough a wide exome­ sequencing (protein-coding genetic alphabet…

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