CA125 do not correlate with pain and its severity among adolescents

CA125 do not correlate with pain and its severity among adolescents By Ellen Tumimbang

Cancer antigen 125 (CA125) is a high molecular weight glycoprotein expressed in tissue derived from the coelomic and Mullerian epithelia including the uterus endometrium. Previous studies reported that CA125 is the most studied endometriosis marker. Women with endometriosis experienced different…

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Dyspareunia and Endometriosis

Dyspareunia and Endometriosis By Irem Onur

Women experience severe pain during intercourse related to endometriosis and this has a significant negative impact on the lives of women. This is according to an American study published in the "Journal of Pain Research". The study included 638 endometriosis…

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Sexual Quality of Life in Women With Endometriosis

Sexual Quality of Life in Women With Endometriosis By Özge Özkaya

Painful intercourse, more severe period pain, worse health-related quality of life, and unemployment are all associated with worse sexual quality of life in women with endometriosis. This is according to a Dutch study published in the scientific journal Sexual Medicine.…

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Pain and Quality of Life Following Surgical Treatment for Endometriosis

Pain and Quality of Life Following Surgical Treatment for Endometriosis By Ellen Tumimbang

Currently, laparoscopy is the preferred approach as a surgical treatment of endometriosis. Many studies have shown the effectiveness of laparoscopic surgery to reduce the painful symptoms and improve the quality of life for patients with endometriosis in the short term…

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The effect of endometriosis on the quality of life

The effect of endometriosis on the quality of life By Hale Goksever Celik

Endometriosis, the disease defined as the localization of endometrial glandular and stromal tissue outside the uterine cavity, can be diagnosed in the reproductive-aged women with an incidence of 7-15%. However, endometriosis is observed in women with chronic pelvic pain syndrome…

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A hope for postoperative symptomatic endometriosis therapy

A hope for postoperative symptomatic endometriosis therapy By Irem Onur

A new chapter in the treatment of symptomatic endometriosis patients may begin since new medical approaches including oral GnRH antagonists, selective progesterone receptor modulators, aromatase inhibitors, and peritoneal immune response modulators are being actively evaluated. To date, there was only…

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Case-control study to develop a questionnaire for early diagnosis of endometriosis

Case-control study to develop a questionnaire for early diagnosis of endometriosis By Nadire Duru

Endometriosis, which affects 5–10% of women of reproductive age, is a chronic gynecological disease characterized by the presence of endometrial glands and stroma outside the uterus, associated with several discomforts such as pelvic pain, menstrual disorders, and infertility. Ultrasound evaluation…

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The Relationship Between Dyspareunia and Infertility in Endometriosis

The Relationship Between Dyspareunia and Infertility in Endometriosis By Selma Oransay

Wahl et al. from the Center of Pelvic Pain and Endometriosis British Columbia Women's Hospital, Vancouver, Canada studied with endometriotic patients suffering from dyspareunia who were referred to their center and built a cross-sectional study to investigate the relations between…

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Surgery and the endometriosis associated-pain: A systematic review

Surgery and the endometriosis associated-pain: A systematic review By Selma Oransay

The surgical approach for pelvic pain-related to endometriosis depends on the stage and the type of the endometriotic lesion and ranging from ablation and the excision of the lesions to radical surgery as hysterectomy with removal of ovaries and presacral…

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Patients preferences for the treatment of endometriosis-associated pain

Patients preferences for the treatment of endometriosis-associated pain By Hale Goksever Celik

Endometriosis is defined as the location of endometrial stroma and glands outside the uterine cavity. The most common presenting complaints are mainly dysmenorrhea, dyspareunia, chronic pelvic pain, and infertility, most of which relate to the menstrual period. Those women affected…

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Clinical trial for the use of oral lactobacillus on endometriosis pain severity

Clinical trial for the use of oral lactobacillus on endometriosis pain severity By Yu Yu

The standard treatment of endometriosis consists of surgery and hormonal based treatment. There is evidence for the efficacy of these types of treatment, although their side effects remain a critical consideration for women. Based on molecular studies, changes in the…

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Sexual distress, metacognitive beliefs, and  endometriosis

Sexual distress, metacognitive beliefs, and  endometriosis By Deniz Kocas

In this study, researchers from the University of Bergamo in Italy investigated the link between sexual distress and psychological and cognitive factors in women with endometriosis. Compared to the general female population, women with endometriosis have a nine-fold increased risk…

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The pain and its severity in deeply infiltrating endometriosis patients

The pain and its severity in deeply infiltrating endometriosis patients By Selma Oransay

Liang et al. from the Department of Obstetrics and Gynecology of the First Affiliated Hospital of Sun Yat-sen University, China, recently published an interesting paper in the Journal of Pain Research, a prospective study to reveal the relationship between neurogenesis and other potential…

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Endometriosis, Pain and Quality of Life

Endometriosis, Pain and Quality of Life By Deniz Kocas

Although studies show that pain in endometriosis is associated with decreased health-related quality of life (HRQoL), details as to which pain symptoms contribute to such a decline have not been explored. For the first time in this study, researchers from…

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How to improve the current ASRM classification of endometriosis?

How to improve the current ASRM classification of endometriosis? By Selma Oransay

In this article which recently published in Best Practice&Research Clinical Obst&Gyn.  from the University of Sao Paulo, Brazil, Andres et al.  penned a review of the classification of endometriosis in chronological order, and discussed the limitations of existing classification systems to…

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Health-related quality of life in women with Endometriosis and Rheumatoid Arthritis

Health-related quality of life in women with Endometriosis and Rheumatoid Arthritis By Murat Osman

Endometriosis is a chronic inflammatory disease that is defined by the presence of ectopic endometrial tissue outside of the uterus. Unfortunately, endometriosis continues to be a leading cause of chronic pelvic pain and long-term morbidity in women of reproductive age.…

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Difficulties Associated with Diagnosing Ascites and Encapsulating Peritonitis in Endometriosis

Difficulties Associated with Diagnosing Ascites and Encapsulating Peritonitis in Endometriosis By Kasthuri Nair

De Magalhães et al. recently published a paper titled “Ascites and Encapsulating Peritonitis in Endometriosis: a Systematic Review with a Case Report” in Revista Brasileira de Ginecologia e Obstetrícia. The team from the Universidade Federal do Ceará and the Universidade…

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Deep Infiltrating Endometriosis Impairs Sexual Function

Deep Infiltrating Endometriosis Impairs Sexual Function By Kasthuri Nair

Lima et al., a group of scientists from Hospital do Servidor Público Estadual in Brazil, recently published an article entitled “Female Sexual Function in Women with Suspected Deep Infiltrating Endometriosis” in Revista Brasileira De Ginecologia E Obstetricia. The paper analyzed…

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Thoracic Endometriosis Syndrome : A case report describing endometriosis involvement of the lung

Thoracic Endometriosis Syndrome : A case report describing endometriosis involvement of the lung By Murat Osman

Leonardo-Pinto and authors from the Universidade Estadual de Campinas, Brazil, have recently published a case report titled, "Hemoptysis and Endometriosis: An Unusual Association - Case Report and Review of the Literature" in the Journal, Revista Brasileira De Ginecologia E Obstetricia describing a…

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Severe Dyspareunia is Related with "Cul-de-sac" and "Uterosacral Ligament" Endometriosis

 Severe Dyspareunia is Related with By Murat Osman

Endometriosis and especially deep infiltrating endometriosis has been associated with an increased risk of severe dyspareunia. Studies reporting the anatomical sites associated with deep dyspareunia and the severity of pain, and the risk factors of these anatomic sites are incongruent;…

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Reduced vascularization in ovarian endometriomas associated with less pain

Reduced vascularization in ovarian endometriomas associated with less pain By Yu Yu

Angiogenesis, i.e., the development of new blood vessels is believed to play an important role in endometriosis pathogenesis and symptoms. Endometriosis is associated and requires neovascularization to proliferate, invade surrounding normal structure in order to establish an endometriotic lesion. Ovarian…

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Combo Therapy of Micronized palmitoylethanolamide/trans-polydatin for Endometriosis Pain

Combo Therapy of Micronized palmitoylethanolamide/trans-polydatin for Endometriosis Pain By Kasthuri Nair

Endometriosis is a painful illness and many researchers in the field work to offer women with the disease some form of respite from the suffering. Indraccolo, Indraccolo, and Mignini are three such researchers and they recently published a paper titled…

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Sexual Pain in Endometriosis

Sexual Pain in Endometriosis By Yu Yu

Pelvic pain during sexual intercourse (deep dyspareunia) is a major concern for women with endometriosis. As many as half of women with endometriosis experience deep dyspareunia and has been shown to have a detrimental impact on quality of life. The…

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Dienogest for endometriosis pain in clinical practice

Dienogest for endometriosis pain in clinical practice By Yu Yu

Dienogest is a synthetic progestogen that has been marketed as a medical treatment for endometriosis. Previous randomized controlled clinical trials have shown that it is effective in women with endometriosis at different stages of the disease. Given its recent introduction,…

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The Benefits of Primary Surgery

The Benefits of Primary Surgery By Kasthuri Nair

Ahmad, Hussin, and Ahmad recently conducted a cohort study, and they published the results within an article titled “An evaluation of the quality of life in women with endometriosis who underwent primary surgery: a 6-month follow-up in Sabah Women &…

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The Unresolved Link Between Sexual Dysfunction and Endometriosis

The Unresolved Link Between Sexual Dysfunction and Endometriosis By Kasthuri Nair

Barbara et al. recently published a systematic review of literature in Reproductive Sciences titled “What Is Known and Unknown About the Association Between Endometriosis and Sexual Functioning” that delves into the effects that endometriosis has on female sexual dysfunction. Endometriosis…

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Does laparoscopic excision or laparoscopic ablation offer the best long-term pain relief from endometriosis?

Does laparoscopic excision or laparoscopic ablation offer the best long-term pain relief from endometriosis? By Murat Osman

This systematic and meta-analysis of several studies aimed to compile data regarding the reduction of dysmenorrhea (menstrual pain), dyschezia (difficult defecation), dyspareunia (painful sexual intercourse), chronic pelvic pain and Endometriosis Health Profile (EHP-30) score 2-12 months after treatment. Visual analog scale (VAS)…

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