By Özge ÖzkayaDysregulated Metabolomic Signatures of Young Patients With Endometriosis
By Özge Özkaya
A new study published in Human Reproduction reveals that adolescents and young adults with endometriosis exhibit significant dysregulation in their plasma metabolomic profiles. In particular, fatty acyls and ceramides were found to be elevated in patients with endometriosis compared to…
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Having Endometriosis Surgery After IVF Better, Study Suggests
By Özge Özkaya
A new study published in Archives of Gynecology and Obstetrics suggests that performing in vitro fertilization (IVF) before surgery may lead to better IVF outcomes for women with endometrioma. To determine the optimal treatment sequence, Dr. Ivan Sini and colleagues from…
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More Young Patients Regret Having a Hysterectomy Than Older Ones
By Özge Özkaya
A study published inObstetrics & Gynecology found that patients aged 30 or younger were more likely to regret their decision to undergo a hysterectomy compared to those aged 31 to 49, regardless of factors such as parity, prior sterilization, or previous…
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By Nasuhi Engin AydinComparison of Postoperative Complications in Total vs. Supracervical Laparoscopic Hysterectomy for Endometriosis
By Nasuhi Engin Aydin
Dr. Raanan Meyer and his team from Cedars-Sinai Medical Center, Los Angeles, have published a study in Archives of Gynecology and Obstetrics, comparing the outcomes of total laparoscopic hysterectomy (TLH) and laparoscopic supracervical hysterectomy (LSCH) in patients with endometriosis. A…
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Integrating Virtual Reality Modeling for Enhanced Surgical Management of Endometriosis
By Özge Özkaya
Transvaginal ultrasound and magnetic resonance imaging (MRI) conducted by experts are generally sufficient for the surgical planning and management of endometriosis, as noted in a recent study published in the Journal of Minimally Invasive Gynecology. However, incorporating novel techniques such as 3D printing…
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By Selma OransayKey Aspects of Ureterolysis in deep endometriosis surgery
By Selma Oransay
Deep endometriosis surgery needs talented surgeons to preserve and protect vital structures during the excision of endometriotic lesions. The technique for ureterolysis is essential to mitigate the risk of ureteral injuries and improve patient outcomes. Dr. Chatroux and Dr. Einarsson…
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Painful Sex Might Be a Valid Indication for Endometriosis Surgery
By Özge Özkaya
According to a new study published in the Journal of Minimally Invasive Gynecology, the type of endometriosis surgery, and pain improvement after surgery may be linked. More precisely, rectovaginal endometriosis surgery may be associated with reduced dyspareunia or painful intercourse. “Clinicians…
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Should I Have Endometriosis Surgery Before IVF-ICSI?
By Özge Özkaya
The live birth rate per in vitro fertilization (IVF) or intrauterine sperm injection (ICSI) cycle was significantly reduced in women who underwent surgery to treat endometriosis before the procedures, found a new study published in the scientific journal Reproductive Sciences. “These…
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Surgery Pivotal in Improving Quality of Life in Endometriosis Patients
By Özge Özkaya
Surgery plays a pivotal role in improving the quality of life of women with endometriosis who have previously not responded to medical therapy. This is according to a new study published in the Journal of Minimally Invasive Gynecology. During the…
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Is Your Surgeon Stressed?
By Özge Özkaya
Stress during endometriosis surgery among surgeons is greater than what they anticipate, according to a new study published in the scientific journal Acta Obstetricia et Gynecologica Scandinavica. The stress symptoms reported by surgeons start before surgery and is more common among…
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The public plea of international group of "endometriosis experts"
By Nasuhi Engin Aydin
A group of international “endometriosis experts” led by Professor Philippe R. Koninckx from Belgium, have published their unique scientific paper “The 10 “Cardinal Sins” in the Clinical Diagnosis and Treatment of Endometriosis: A Bayesian Approach” in a recent issue of…
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Preoperative MRI Scoring System Could Ensure Women Are Fully Informed
By Özge Özkaya
The Deep Pelvic Endometriosis Index is able to predict the length of surgery and hospital stay as well as complications following surgery including voiding dysfunction, according to a new multicenter cohort study, the results of which were published in The Journal…
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A Multidisciplinary Surgical Team Is a Must in Deep Endometriosis Surgery
By Özge Özkaya
Endometriosis must be managed by a team of multidisciplniary specialists, especially in case it causes damage to the digestive tract, according to a new study published in the journal Archives of Gynecology and Obstetrics. According to the authors, the presence…
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Current AAGL Staging System Not Good at Predicting Complexity of Endometriosis Surgery
By Özge Özkaya
The link between the stage of endometriosis as defined by the American Association of Gynecologic Laparoscopists (AAGL) and the level of surgical complexity is weak or moderate, according to a new study published in the Journal of Minimally Invasive Gynecology. …
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Rare but important entity: perineal endometriosis
By Nasuhi Engin Aydin
Dr. Zhu and colleagues from Peking Union Medical College Hospital have published their retrospective research on "surgically treated perineal endometriosis cases" in a recent issue of BMC’s Women’s Health. Perineal endometriosis is a rare type of endometriosis accounting for at…
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Deep Endometriosis Surgery and Women’s Quality of Life
By Özge Özkaya
The physical and social functions as well as the overall physical health is worse than normal among Spanish women who underwent surgery for deep endometriosis, reported a new study published in the Journal of Clinical Medicine. The bodily pain, emotional…
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Minimally Invasive Surgery Improves the Quality of Life of Women With Deep Infiltrating Endometriosis
By Özge Özkaya
Minimally invasive surgery improves the quality of life of women with deep infiltrating endometriosis two years after the operation, according to a new study published in the Journal of Clinical Medicine. The results are similar between conservative and total surgery.…
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Scientists Try to Understand Consequences of Genetic Changes in Endometriosis
By Özge Özkaya
The protocol of the "Endometriosis Research Queensland Study" has been published in the scientific journal BMJ Open. The aim of the study is to collect endometrial tissue associated with the disease and chart its genetic architecture. This way, the researchers aim to…
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Surgery Improves the Sex Life and Sleep of Women With Endometriosis
By Özge Özkaya
Endometriosis surgery improves patients’ quality of life, sexual function, and sleep confirms a new study by Turkish researchers published in the scientific journal Archives of Gynecology and Obstetrics. According to the first author Dr. Belfin Nur Arici Halici of the…
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Surgery for the Treatment of Endometriosis of the Diaphragm and Thorax
By Özge Özkaya
Diaphragmatic and thoracic endometriosis starts in the abdominal wall of the diaphragm and later invades the thorax, based on findings from a series of patients surgically treated for the disease, reports a study published in the Journal of Gynecology Obstetrics…
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By Eylül GÜNWhich surgical technique is best for rectal endometriosis?
By Eylül GÜN
One of the common sites for deep endometriosis is the intestines, with a rate of 3-37%. Intestinal endometriosis constitutes a serious cause of gastrointestinal symptoms, pain, and the alteration of the quality of life, with the rectum and sigmoid colon being…
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Effects of Bowel Endometriosis Surgery on Mode of Delivery
By Özge Özkaya
Less than a third of doctors counsel women about the possible effects of surgical treatment of bowel endometriosis on their mode of delivery should they become pregnant, according to a new study published in the Journal of Obstetrics and Gynaecology.…
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Surgery before in-vitro fertilization – Is it beneficial in patients with deep endometriosis?
By Eylül GÜN
Deep pelvic endometriosis is thought to be related to infertility by altering the pelvic environment and anatomy due to pelvic adhesions, and the changes in endometrial receptivity contribute to it. The discussion on whether the surgical intervention was beneficial started…
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How likely is it to get pregnant and have a baby after undergoing surgery for high stage endometriosis?
By Eylül GÜN
As one of the most common causes of infertility in women, endometriosis might be surgically interfered with depending on the stage. For Stage I and II endometriosis, surgery is recommended in the latest guidelines to ameliorate fertility rates, however, there…
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How Likely Am I to Conceive After Endometriosis Surgery?
By Özge Özkaya
Women with superficial peritoneal endometriosis and just one type of lesion are more likely to conceive after surgery, according to a new study published in the International Journal of Gynecology and Obstetrics. This is important because patients will be better…
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New Endometriosis Clinical Trial Now Recruiting Participants
By Özge Özkaya
A new clinical trial investigating the effect of cognitive-behavioral therapy on quality of life in patients undergoing surgery for endometriosis is now recruiting participants. The randomized, controlled trial aims to recruit 100 participants, ages 18 to 50 with proven endometriosis…
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How to measure the length of recto-sigmoid deep endometriosis reliably?
By Eylül GÜN
An in-depth assessment is needed when rectosigmoid deep endometriosis is decided to be treated surgically. Surgery carries a lot of risks and it is not always easy to decide which procedure the patient would benefit the most from. Patient-oriented surgical…
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By Bahar YukselPostoperative Opioid use after Robotic operations for endometriosis, compared to non-endometriosis
By Bahar Yuksel
Endometriosis is a common disease in patients of fertile age, and many patients require surgery. Robotic surgery is accepted as a minimally invasive method in the management of endometriosis and other benign conditions. However, postoperative pain status and the best pain…
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Adhesion Barrier Helps After Endometriosis Surgery
By Özge Özkaya
An adhesion barrier, named "4DryField® PH" significantly reduced the formation of adhesions following endometriosis surgery, according to a new study by German scientists. The formation of adhesions following endometriosis surgery is a severe problem that affects 90% of patients. The…
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What Happens to Endometriosis Patients After Endometriosis Surgery?
By Özge Özkaya
Although few patients with endometriosis who undergo a hysterectomy need repeat surgery, up to 25% of them need minor surgery. Around 20% of patients who undergo conservative surgery with ovarian preservation require additional endometriosis surgery. Up to one in three…
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KEYNOTE: Excision Without Mutilation: It’s Possible! - Arnaud Wattiez, MD
By Özge Özkaya
In his keynote lecture, Dr. Wattiez talks about the pros and cons of endometriosis surgery and the importance of tailoring endometriosis surgery to individual patients. “Endometriosis is a disease that degrades patient’s wellbeing," Dr. Wattiez says and gives some examples…
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Exploring the Role of Neuropathy in Re-Operative Endometriosis - Marc Possover, MD, PhD
By Özge Özkaya
Prof. Possover starts his presentation by summarizing the possible cause of pelvic neuropathy following endometriosis surgery. Pelvic neuropathy is the damage or dysfunction of the pelvic nerve. Prof. Possover explained that this could either be due to incomplete surgery, disease…
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Operative techniques for Deep Endometriosis Surgery - Shaheen Khazali, MD
By Özge Özkaya
In this presentation, Dr. Shaheen Khazali, an endometriosis surgeon specialized in gastrointestinal and urinary tract endometriosis excision and in neuropelveology, talks about the general principles and some techniques for endometriosis surgery focusing on rectovaginal endometriosis. He also describes the "ten…
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Role of Prophylactic Oophorectomy in Endometriosis Patients with Ovarian Cancer History in the family - Farr Nezhat, MD
By Özge Özkaya
Dr. Nezhat starts his presentation by outlining his objectives, which are to review the basics of cancer genetics, give an overview about endometriosis and ovarian cancer, discuss the pathogenesis of malignant transformation of endometriosis, and talk about the clinical implications…
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By Dr. Youngran ParkA Possible genetic target for endometriosis treatment
By Dr. Youngran Park
Mutations in the chromosome remodeling complex SWI/SNF subunit ARID1A were first identified in ovarian clear-cell carcinoma and ovarian endometrioid carcinoma, two endometriosis-associated epithelial ovarian cancer subtypes. ARID1A gene mutations are also observed in deep ovarian and deep infiltrating endometriosis, atypical endometrial…
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Hysterolaparoscopy Plus Assisted Reproduction Improves Fertility in Women with Endometriosis
By Özge Özkaya
Hysteroscopy and laparoscopic surgery is an effective and reliable therapeutic procedure, confirmed a study published in the "Journal of Clinical Medicine". The approach is even more effective when combined with assisted reproductive techniques such as artificial insemination and in vitro…
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Endometriosis Severity and Complication Risks Following Laparoscopic Surgery
By Özge Özkaya
In a research article published in the journal Acta Obstetricia et Gynecologica Scandinavica, researchers at Brigham and Women's Hospital in Boston, Massachusetts suggested that the severity of endometriosis could not be a predictor of the risk of post-operative complications. In…
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What we should know in managing infertility related to endometriosis?
By Nasuhi Engin Aydin
Dr. Llarena and associates made a comprehensive review of the causes of infertility in endometriosis and adverse effects of surgical procedures in Clinical Medicine Insights: Reproductive Health. Infertility is an important issue in endometriosis patients and about 30-50 % face infertility.…
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What do Women with Endometriosis Think About the Medical Profession?
By Özge Özkaya
Failure of surgical treatment, use of the emergency room, and access to complementary healthcare are factors associated with a negative perception of the medical profession in women with endometriosis. This is according to a study conducted by researchers in British…
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Does the Severity of Endometriosis Increase the Risk of Complications Following Surgery?
By Özge Özkaya
The severity of endometriosis cannot predict the risk of complications after laparoscopy. Instead, the complexity of the surgical procedure itself may increase the risk of complications. This is according to a study published in the journal "Acta Obstetricia et Gynecologica Scandinavica".…
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By Timur SeckinHow to predict complications for endometriosis surgery?
By Timur Seckin
In a new study co-led by scientists at Sorbonne University, a nomogram is built to better inform patients about the risk of deep endometriosis surgery without bowel involvement. The findings have been published in the European Journal of Obstetrics &…
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Patients with Pelvic Pain Most Likely to Benefit from Endometriosis Surgery
By Özge Özkaya
Women who experience higher levels of pain are more likely to show improvement in their quality of life (QoL) following endometriosis surgery, according to a study published in The Journal of Minimally Invasive Gynecology. Chronic pelvic pain seems to be…
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By Murat OsmanEndometriosis involving the superficial peritoneum in Adolescents: Surgical Management
By Murat Osman
Endometriosis is a chronic disease whereby endometrial glands and stroma grow and survive outside of the uterus. In some cases, endometriosis may become symptomatic and cause debilitating, chronic pelvic pain. Among pelvic organ and other surfaces that endometriosis can involve…
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By Hale Goksever CelikHow to predict natural conception in women underwent endometriosis surgery?
By Hale Goksever Celik
Endometriosis is defined as the localization of endometrial glandular and stromal cells outside the uterine cavity. The most common symptoms are dysmenorrhea, dyspareunia, chronic pelvic pain, and infertility. The prevalence of endometriosis increases in the infertile population. Thus, the important…
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Will I Have Complications After Endometriosis Surgery?
By Özge Özkaya
The rate of complications after surgery to treat deep infiltrating endometriosis is low, confirmed a study by researchers in Germany. It is important to know whether major or minor complications following surgery are likely to develop and what the outcome…
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IVF Is the Best Option to Become Pregnant for Women with Severe Endometriosis, or Is It Not?
By Özge Özkaya
Treating rectal endometriosis with surgery seems to increase the chance of a woman conceiving, with most pregnancies occurring naturally. This is according to a study published in the medical journal Human Reproduction. The optimal treatment for women with severe endometriosis…
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By Irem OnurEndometrioma and endometriosis
By Irem Onur
Exacoustos C. et al. published an article titled “The isolated ovarian endometrioma: a history between myth and reality” in the Journal of Minimally Invasive Gynecology in 2018. They aimed to examine the association between ovarian endometriomas detectable at the transvaginal ultrasound…
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How are endometriosis patients managed clinically?
By Irem Onur
This review paper by Falcone and Flyckt, entitled “Clinical Management of Endometriosis” published in the journal Obstetrics & Gynecology aims to summarize the current strategies for treating endometriosis patients with pain, pelvic dysfunction, and subfertility related to their disease. There are many…
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Prior endometriosis surgery and the risk of pregnancy complications
By Irem Onur
Koninckx et al. discussed the association of pregnancy complications with endometriosis and endometriosis surgery in their recently published paper in the journal Fertility and Sterility. They especially mentioned about the retrospective study of Nirgianakis et al. published in the same…
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By Kasthuri NairA Doctor's Guide to Making Endometriosis Less Scary
By Kasthuri Nair
Canis, Bourdel, and Chauvet, doctors from CHU Estaing, recently published an article titled “Endometriosis: frightening the patients is not an acceptable alternative to inadequate surgical management and or pathophysiology ignorance” in Fertility and Sterility. Their paper delineated proper health practices…
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How to identify an Expert Centers for Colorectal Endometriosis Surgery
By Özge Özkaya
It is of paramount importance to determine set criteria to define expert centers for colorectal endometriosis surgery, according to a research article published in the scientific journal Surgical Endoscopy. As the hospital and surgeon case volume has a significant impact…
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Best Time for IVF Between 7 and 25 Months Post Surgery Study Suggests
By Özge Özkaya
The more severe endometriosis is, the lower the success rate of IVF, according to a new study published in the Journal of Minimally Invasive Gynecology. However, the presence of endometriosis as such does not seem to affect the outcome of…
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