Colorectal Deep Endometriosis Resection and Potential Complications

Colorectal Deep Endometriosis Resection and Potential Complications By Murat Osman

A severe clinical form of endometriosis, deeply infiltrating endometriosis (DIE) is characterized by more aggressive endometriotic lesions commonly involving deeper pelvic or gastrointestinal organs. It causes significant quality of life impairment and morbidity and is increasingly associated with infertility. When…

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Deep Endometriosis or Recto-uterine Obliteration Without Endometrioma

Deep Endometriosis or Recto-uterine Obliteration Without Endometrioma By Selma Oransay

The diagnostic help of ultrasound is increasing by its ability to diagnose deep infiltrating and rectouterine pouch obliteration in patients who are suffering from chronic pelvic pain. Clinicians are used to evaluating the rectal and parametrial areas of the endometriotic…

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Inhibiting killer on the move

Inhibiting killer on the move By Yu Yu

The three main forms of endometriosis are superficial, ovarian, and deep endometriosis. The latter is defined by the presence of endometriotic nodules that are deeper than 5 mm. Deep endometriosis is considered the most aggressive and is associated with severe…

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Endometriosis prevalence among adolescents with pelvic pain

Endometriosis prevalence among adolescents with pelvic pain By Irem Onur

An updated review conducted by the investigators at EGA Institute for Women's Health, University College London, United Kingdom, in collaboration with Birmingham Women’s and Children’s Foundation Trust of the Institute of Metabolism and Systems Research at the University of Birmingham…

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Reproductive capacity and recurrence rate after surgery for Stage III/IV endometriosis 

Reproductive capacity and recurrence rate after surgery for Stage III/IV endometriosis  By Bahar Yuksel

If gaining fertility back is the main goal, the surgical removal of endometriosis lesions is globally recognized as first-line therapy. Even though, pre- and postoperative hormone therapy leads to a significant decrease in the spread of the disease measured with the…

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Fallopian tubes and endometriosis

Fallopian tubes and endometriosis By Selma Oransay

There are multiple theories to explain the pathogenesis of endometriosis, among which the most popular one is Sampson's retrograde menstruation theory. The role of endometrial stem cells/progenitors are widely studied to support the origin of ectopic lesions in recent decades.…

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Hormone Control Related Genes in Women With Endometriosis

Hormone Control Related Genes in Women With Endometriosis By Ellen Tumimbang

Endometriosis is an estrogen-dependent disease.  The development of endometriosis is stimulated by the specific ability to receive the estrogen that is needed for growth and differentiation of endometrial cells and has numerous biological functions in eutopic and ectopic endometrium. Estrogen…

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The impact of obesity on safety and feasibility of laparoscopic endometriosis surgery

The impact of obesity on safety and feasibility of laparoscopic endometriosis surgery By Hale Goksever Celik

The quality of life in the women affected by endometriosis depends on the symptoms and signs of endometriosis such as dysmenorrhea, dyspareunia, chronic pelvic pain, and infertility. The most common locations of endometriosis are ovary, ovarian fossa, uterosacral ligament, and…

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Anogenital distance and endometriosis

Anogenital distance and endometriosis By Timur Seckin

Endometriosis may be associated with exposure of the embryo to chemicals called ‘endocrine disruptors’. Exposure to endocrine disruptors can be estimated by measuring the anogenital distance (i.e. the distance between the clitoris and the anus), using a centimeter ruler with…

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The effect of endometriosis on the quality of life

The effect of endometriosis on the quality of life By Hale Goksever Celik

Endometriosis, the disease defined as the localization of endometrial glandular and stromal tissue outside the uterine cavity, can be diagnosed in the reproductive-aged women with an incidence of 7-15%. However, endometriosis is observed in women with chronic pelvic pain syndrome…

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Menstrual Blood Proteins for Endometriosis Diagnosis

Menstrual Blood Proteins for Endometriosis Diagnosis By Ellen Tumimbang

Endometriosis is a gynecological disorder characterized by endometrial tissue outside the uterine cavity. The backflow of menstrual blood from the uterus through the fallopian tubes is thought to be the cause of endometrial tissue growing outside the uterine cavity when…

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Opioids use in women with endometriosis, what does it tell us?

Opioids use in women with endometriosis, what does it tell us? By Yu Yu

Endometriosis is a debilitating disease that can cause many painful symptoms such as dysmenorrhea, dyspareunia, infertility, chronic pelvic pain, abdominal pain, and sacral or low back pain. More than half of women diagnosed with endometriosis suffer from chronic pelvic pain.…

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Endometriosis surgery and future pregnancy complications

Endometriosis surgery and future pregnancy complications By Selma Oransay

Endometriosis is one of the known diseases for infertility in the reproductive period of women. Several studies revealed that endometriosis itself maybe the reason for some unfavorable obstetric outcomes. Localization, the type of endometriotic lesions, and the stage of endometriosis…

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Risk Factors Associated with Ureteral Endometriosis

Risk Factors Associated with Ureteral Endometriosis By Özge Özkaya

Patients with severe endometriosis, uterosacral ligament deep involvement with endometriosis lesions of  3 cm in diameter or more, and the presence of previous endometriosis surgery have a significantly higher risk of having ureteral endometriosis. This is according to a study…

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Progressive nature of ovarian endometrioma

Progressive nature of ovarian endometrioma By Yu Yu

The effective management of endometriosis requires a proper understanding of how the condition progress as women age, especially for those women with early onset of endometriosis. Several studies have tried to characterize the evolution of endometriosis. Some of the key…

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Interleukin-37b inhibits the growth of murine endometriosis-like lesions

Interleukin-37b inhibits the growth of murine endometriosis-like lesions By Nadire Duru

Endometriosis is a chronic gynecological disease that causes chronic pain and infertility in women. Despite continuous efforts and numerous research, there is, ultimately, still much to understand about the pathogenesis of endometriosis. Inflammatory factors including several interleukins have already been…

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Cycle-related gastrointestinal complaints in reproductive age young women

Cycle-related gastrointestinal complaints in reproductive age young women By Timur Seckin

An analysis of 1-year data on 266 patients who presented to the Clinic and Polyclinic for Gynecology and Reproductive Medicine at Jena University Hospital to undergo surgery for endometriosis and its symptoms was performed by Nicolaous K. et al., a…

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The prevalence and severity of endometriosis today

The prevalence and severity of endometriosis today By Irem Onur

Ghiasi M. et al., a group of researchers from the USA, presented a comprehensive review of the prevalence, incidence, and stage of endometriosis worldwide as reported over the past 30 years. Researchers performed a search in four databases, including PubMed,…

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Endometriosis features vs Patient age

Endometriosis features vs Patient age By Dr. Youngran Park

Endometriosis, a common gynecological disease, has significant negative impacts on patients’ daily life. Especially in younger women who have yet to achieve pregnancy, effective management should consider the disease progression. Though it is still under debate, some people suggest that…

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Is there any difference between endometriosis patients with or without obliterated cul-de-sac during laparoscopic hysterectomy?

Is there any difference between endometriosis patients with or without obliterated cul-de-sac during laparoscopic hysterectomy? By Hale Goksever Celik

Endometriosis is a disease defined as the localization of endometrial glandular and stromal cells outside the uterine cavity. It is diagnosed in 10% to 15% of reproductive-aged women. Women with endometriosis demand therapy for the most common symptoms, which are…

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How to predict complications for endometriosis surgery?

How to predict complications for endometriosis surgery? By Timur Seckin

In a new study co-led by scientists at Sorbonne University, a nomogram is built to better inform patients about the risk of deep endometriosis surgery without bowel involvement. The findings have been published in the European Journal of Obstetrics &…

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The use of Elagolix in Women with Liver and Kidney Impairments

The use of Elagolix in Women with Liver and Kidney Impairments By Özge Özkaya

Elagolix may be used in women with moderate liver impairment, when necessary, for up to six months at a dose of 150 mg a day, according to a study published in the scientific journal Clinical Pharmacology in Drug Development. The…

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A Better Way to Diagnose Endometriosis?

A Better Way to Diagnose Endometriosis? By Özge Özkaya

Three proteins found in the blood and endometrial tissues could be used to determine the stage of endometriosis and the severity of painful periods according to a study published in the journal Current Medical Science. Evaluating the levels of these…

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Does Endometriosis Cause Infertility?

Does Endometriosis Cause Infertility? By Özge Özkaya

Infertility may be related to the localization of endometriosis involvement according to a study published in the Journal of Obstetrics and Gynaecology. This finding is in agreement with the results of previous studies and could help clinicians in their decision…

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