Exposure to toxic metals and the risk of endometriosis

Exposure to toxic metals and the risk of endometriosis By Selma Oransay

Mercury, lead, and cadmium are the best-studied heavy metals for several adverse effects on the human reproductive system. Mercury can induce DNA damage, oxidative stress, and mitochondrial dysfunction, and lead exposure is associated with menstrual disorders, preterm birth, and miscarriage.…

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Endometriosis and environmental factors

Endometriosis and environmental factors By Selma Oransay

The estrogen-dependent nature of endometriosis has generally led to search endocrine-based causes. Especially, polychlorinated biphenyls, dioxins, and Dietilstilbesterol are the most studied chemicals in the literature. Interesting data that needs confirmation in the future also suggest a link with night…

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Geography May Influence Risk of Endometriosis

Geography May Influence Risk of Endometriosis By Özge Özkaya

The risk of developing endometriosis seems to be geographically heterogeneous across France, according to results from a study published in the journal Scientific Reports. The study identified  20 high-risk hotspots around the country. These showed similar results for non-adenomyosis endometriosis…

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 Which of the suggested environmental risk factors are indeed related to endometriosis?

 Which of the suggested environmental risk factors are indeed related to endometriosis? By Eylül GÜN

Endometriosis is a complex disease with genetic and environmental factors in its poorly understood pathogenesis. Even though many epidemiological studies in the literature have proposed several risk factors, the lack of clear establishment and modification of these potential risk factors…

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Environmental factors play a role in the development of endometriosis

Environmental factors play a role in the development of endometriosis By Hale Goksever Celik

The proposed mechanisms underlying the development of endometriosis may be classified into three groups: in-situ theory, implantation theories, and induction theories. Genetic, hormonal, environmental, and lifestyle-related factors are also involved as no mechanism is solely responsible for endometriosis development. Although there are…

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Lead and cadmium exposures of female workers should be reduced as much as possible

Lead and cadmium exposures of female workers should be reduced as much as possible By Nasuhi Engin Aydin

Min-Gi Kim and associates from Korea published their results on the possible effects of lead and cadmium exposure in endometriosis induction and severity in a recent issue of “International Journal of Environmental Research and Public Health”. Endometriosis is an illness…

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Chemical Found in Self-Care Products May Be Linked to Endometriosis

Chemical Found in Self-Care Products May Be Linked to Endometriosis By Özge Özkaya

There may be a link between exposure to phthalates and endometriosis according to a new study published in the Journal of Assisted Reproduction and Genetics. Although more research is needed, these findings could be translated into clinical practice according to…

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Strong Geographical Gradient in Endometriosis Incidence Identified

Strong Geographical Gradient in Endometriosis Incidence Identified By Özge Özkaya

The geographical distribution of new endometriosis cases showed a very strong north-south spatial gradient in the highly industrialized Friuli Venezia Giulia region of Italy, according to a new study published in the International Journal of Environmental Research and Public Health. “The cluster of…

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How to unveil the discrepancy regarding the effect of chemicals on the etiology of endometriosis

How to unveil the discrepancy regarding the effect of chemicals on the etiology of endometriosis By Nasuhi Engin Aydin

Kristen Upson from Michigan State University published a review article evaluating research papers on environmental factors effective in endometriosis from an epidemiological perspective in "Current Epidemiology Reports". Endometriosis is a multifactorial disease with anatomical, hormonal, immunological, estrogenic, genetic, epigenetic, and…

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Anogenital distance and endometriosis

Anogenital distance and endometriosis By Timur Seckin

Endometriosis may be associated with exposure of the embryo to chemicals called ‘endocrine disruptors’. Exposure to endocrine disruptors can be estimated by measuring the anogenital distance (i.e. the distance between the clitoris and the anus), using a centimeter ruler with…

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An important environmental contaminant dioxin has links to the pathogenesis of endometriosis

An important environmental contaminant dioxin has links to the pathogenesis of endometriosis By Nasuhi Engin Aydin

Giampaolinoa and associates from the University of Genoa, Italy published a review on environmental contaminant dioxin and its possible epigenetic role related to endometriosis development in "Gynecological Endocrinology". The authors made a narrative review, with the results of their search…

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Babies Born Lighter May Have a Higher Risk of Developing Endometriosis Later in Life

Babies Born Lighter May Have a Higher Risk of Developing Endometriosis Later in Life By Özge Özkaya

Being exposed to growth restriction before birth seems to be associated with a higher risk of developing endometriosis during a woman’s reproductive years. Other factors such as having fewer liveborn children and prior infertility problems, also seem to be important…

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Can early-life exposures affect endometriosis development later in life?

Can early-life exposures affect endometriosis development later in life? By Demet Candaş Green

Endometriosis is a complex disease with possible multifactor contributors. So far, inflammatory, immunogenic, genetic, and environmental factors have all been associated with endometriosis. In addition, it is possible that different types of endometriosis lesions – peritoneal, ovarian, and deep infiltrating…

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Immune dysregulation in endometriosis

Immune dysregulation in endometriosis By Yu Yu

The connection between endometriosis and the immune system has long been proposed. However, to date, there is no real consensus on whether immune adaptations actually facilitate endometriotric lesion progression or they are a consequence of endometriosis re-occurrence. Thus, this article…

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Fighting with endometriosis

Fighting with endometriosis By Irem Onur

Maduro M.R. reviewed three separate studies on potential new targets to successfully manage endometriosis in her recent paper titled “Novel Strategies to Fight Endometriosis” published in the journal Reproductive Sciences. In the autotransplantation rat model of Torres-Reveron et al., the…

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The pathogenesis of endometriosis : New discoveries with clinical impact

 The pathogenesis of endometriosis : New discoveries with clinical impact By Nasuhi Engin Aydin

In this recent review article that appeared in Current Women’s Health Reviews, compiled by researchers from the Department of Molecular Cell Biology and Human Genetics, Institute of Cell Biology and Neuroscience Frankfurt, Germany the following important points in regard to the molecular and cellular pathogenesis of…

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How do adolescent girls and boys perceive symptoms suggestive of endometriosis among their peers?

How do adolescent girls and boys perceive symptoms suggestive of endometriosis among their peers? By Dr. Youngran Park

Endometriosis, a chronic condition characterized by cells similar to the uterine lining that exist outside of the uterus, is estimated to impact 10% of women of reproductive age. In the USA, that approximates to some 7.4 million women. Endometriosis has…

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