Assessing endometrial receptivity using menstrual blood samples in patients undergoing in-vitro fertilization

Assessing endometrial receptivity using menstrual blood samples in patients undergoing in-vitro fertilization By Eylül GÜN

Endometrial receptivity is the endometrium's capacity to allow the embryo the chance to adhere, infiltrate, and develop while ensuring an ideal microenvironment. When impaired, it is one of the two major factors contributing to infertility along with embryo quality by…

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How Good is Ultra-Long GnRH-a Treatment Before IVF for Women With Endometriosis?

How Good is Ultra-Long GnRH-a Treatment Before IVF for Women With Endometriosis? By Özge Özkaya

Pretreatment with ultra-long gonadotropin-releasing hormone agonist (GnRH-a), i.e. for at least three months before in vitro fertilization (IVF), has an adverse effect on patient pregnancy outcomes with endometriosis, according to a meta-analysis of the literature published in the Journal of…

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Comparison of different IVF stimulation protocols for pregnancy success in infertile endometriosis patients

Comparison of different IVF stimulation protocols for pregnancy success in infertile endometriosis patients By Hale Goksever Celik

Women with endometriosis may suffer from reproductive problems up to an incidence of 50%. Several pathophysiological mechanisms including anatomic distortion, alterations in endometrial receptivity, diminished tubal peristalsis and sperm movements are the most responsible for the development of endometriosis-associated infertility.…

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Conventional IVF or ICSI: Which one is more accurate in endometriosis-related infertility?

Conventional IVF or ICSI: Which one is more accurate in endometriosis-related infertility? By Hale Goksever Celik

Although the prevalence of endometriosis is 10-15% in the general population at reproductive age, it is diagnosed more frequently in infertile women with a prevalence of 25-40%. Although the exact mechanism explaining the association between endometriosis and infertility has not…

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The emotions and experiences of women with endometriosis during and after pregnancy

The emotions and experiences of women with endometriosis during and after pregnancy By Eylül GÜN

It is well-known that endometriosis patients have a high rate of infertility and a hard time getting pregnant compared to women without endometriosis. Despite the belief that pregnancy can alleviate endometriosis symptoms, some studies have shown that women with endometriosis…

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Women With More Severe Endometriosis Have Fewer Eggs

Women With More Severe Endometriosis Have Fewer Eggs By Özge Özkaya

Severe endometriosis negatively affects ovarian response and the quality of oocytes and embryos, according to a new study published in JBRA Assisted Reproduction. However, the rate of fertilization does not seem to be affected by endometriosis stage.  These findings could…

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Ovarian endometriomas, ovarian reserve, oocyte quality and IVF/ICSI outcomes

 Ovarian endometriomas, ovarian reserve, oocyte quality and IVF/ICSI outcomes By Selma Oransay

Surgery and assisted reproductive technology (ART) are the preferred treatments for endometrioma in infertile patients. When ART is considered, surgery may seem to have no advantages, as it may not improve pregnancy outcomes and may carry the risk of decreasing…

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Endometriosis and the cumulative live birth rate in IVF cycles.

Endometriosis and the cumulative live birth rate in IVF cycles.  By Hale Goksever Celik

Infertility is one of the symptoms encountered in up to 40-50% of women with endometriosis. There are several pathophysiological theories suggesting the development of endometriosis-associated infertility. Assisted reproductive technology (ART) using in vitro fertilization and embryo transfer (IVF-ET) has been…

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The Oocyte Quality in Ovarian Endometriosis

The Oocyte Quality in Ovarian Endometriosis By Selma Oransay

Endometrioma is the ovarian involvement of endometriosis affecting up to 44% of women diagnosed with the disease. Owing to the anatomical locus, ovarian endometriosis may impair folliculogenesis and oocyte competence, differing from other forms of endometriosis.  When investigating the relationship between…

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Fertility assessment and surgical approach in endometriotic patients.

Fertility assessment and surgical approach in endometriotic patients. By Selma Oransay

The prevalence of endometriosis is around 50-70% in women with pelvic pain, and it has been reported as 50% in patients with infertility. Severe adhesive disease associated with advanced endometriosis is a cause of fertility impairment. The relationship between endometriosis…

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Does endometrioma affect ovarian reserve to reach pregnancy and birth?

Does endometrioma affect ovarian reserve to reach pregnancy and birth? By Hale Goksever Celik

Endometrioma occurs in approximately 17-44% of women with endometriosis. These women suffer from dysmenorrhea, dyspareunia, chronic pelvic pain, and also infertility. Although the exact mechanism explaining endometriosis-associated infertility has not been elucidated, distorted pelvic anatomy, impaired ovarian function, altered microenvironment-endometrial receptivity,…

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Surgery before in-vitro fertilization – Is it beneficial in patients with deep endometriosis?

Surgery before in-vitro fertilization – Is it beneficial in patients with deep endometriosis? By Eylül GÜN

Deep pelvic endometriosis is thought to be related to infertility by altering the pelvic environment and anatomy due to pelvic adhesions, and the changes in endometrial receptivity contribute to it. The discussion on whether the surgical intervention was beneficial started…

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Is intrauterine insemination effective in women having endometriosis-associated infertility?

Is intrauterine insemination effective in women having endometriosis-associated infertility?  By Hale Goksever Celik

The most common presenting complaints of women with endometriosis are dysmenorrhea, dyspareunia, chronic pelvic pain, and infertility. Affected women demand therapy for these symptoms of endometriosis, notably fertility problems. Several underlying mechanisms have been proposed to explain endometriosis-associated infertility including anatomic…

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Placenta praevia and cesarean section more common in patients with ART for Endometriosis

Placenta praevia and cesarean section more common in patients with ART for Endometriosis By Hale Goksever Celik

Even though endometriosis is known to be associated with infertility, these women still have a chance to get pregnant spontaneously or by assisted reproduction techniques (ART) with the aid of recent technological developments. A It has also been shown that…

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Impact of surgery before IVF in infertile women with endometrioma

Impact of surgery before IVF in infertile women with endometrioma By Hale Goksever Celik

Among the women with endometriosis, 30 to 50% are estimated to have infertility. On the contrary, among women who present with infertility, 25 to 50% are estimated to also have endometriosis. Several mechanisms have been proposed to explain the association…

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Non-invasive Construction of Endometrial Organoids

Non-invasive Construction of Endometrial Organoids By Eylül GÜN

Organoids are 3D culture structures established in vitro and they reflect the aspects of the tissue or the organ they represent. They are seen as important tools in the evaluation of normal development, disease course, and the prediction of the…

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Progestin suppression for endometriosis before IVF

Progestin suppression for endometriosis before IVF By Hale Goksever Celik

“Dienogest is a suitable and safe substitute for GnRHa pretreatment in endometriosis patients”, according to the Khalifa et al., from Egypt. Endometriosis is one of the leading reasons for infertility due to decreased oocyte/embryo quality, fertilizability, tubal function, and aberrant endometrial…

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Optimal management of infertility in endometriosis patients

Optimal management of infertility in endometriosis patients By Hale Goksever Celik

Pelvic pain and infertility are the main symptoms of endometriosis patients. Although the pathophysiological mechanism for infertility is not clearly understood, there are several theories explaining decreased fertility potential in women with endometriosis. Ata and Telek, from Koc and Istanbul Universities…

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Fertilization rate and pregnancy outcome in IVF cycles of endometriosis.

Fertilization rate and pregnancy outcome in IVF cycles of endometriosis. By Selma Oransay

Endometriosis affects the pelvic cavity, uterus, ovaries and causes impaired fertility as a result. The chronic inflammatory nature of this disease negatively impacts the oocyte quality, maturation, and fertilization. Obviously, fewer oocytes can be harvested in the IVF cycles of…

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Endometriosis, ART, fertility preservation

Endometriosis, ART, fertility preservation By Selma Oransay

This review entitled "The impact of endometriosis on the outcome of assisted reproductive techniques: role of fertility preservation" was written by Necula et al. from Gynecology and Obstetrics Unit, Biel, Switzerland, and recently published in the journal "Hormone, Molecular Biology and Clinical…

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Impaired fertility potential in endometriosis patients

Impaired fertility potential in endometriosis patients By Hale Goksever Celik

Infertility is frequently encountered in endometriosis patients because of anatomic distortion, alterations in endometrial receptivity, diminished tubal peristalsis and sperm movements. Garcia-Fernandez and García-Velasco, from Edinburgh, UK and Madrid, Spain, published a mini-review titled “Endometriosis and Reproduction: What We Have…

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Live Birth Rate in Women Who Underwent Fresh Embryo Transfer Using Freshly Retrieved Donor Oocytes

Live Birth Rate in Women Who Underwent Fresh Embryo Transfer Using Freshly Retrieved Donor Oocytes By Hale Goksever Celik

One of the important clinical findings in women with endometriosis is reproductive problems. Infertility can be encountered in up to 50% of women with endometriosis and up to 50% of women with infertility can be diagnosed with endometriosis. Several pathophysiologic…

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Egg Freezing for Endometriosis: Should she rush - Tomer Singer, MD

Egg Freezing for Endometriosis: Should she rush - Tomer Singer, MD By Özge Özkaya

In this presentation, Dr. Tomer Singer, a fertility specialist and the medical director at Shady Grove Fertility in Manhattan, New York talks about egg freezing and its importance for women with endometriosis. He emphasizes the importance of having an endometriosis…

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Implantation failure in endometriosis patients - Jovana Lekovich, MD., PhD.

Implantation failure in endometriosis patients - Jovana Lekovich, MD., PhD. By Hale Goksever Celik

Endometriosis is one of the leading reasons for infertility due to decreased oocyte/embryo quality, fertilization ability, tubal function, and aberrant endometrial receptivity. Whether this failure is caused by oocyte/embryo or eutopic endometrium is one of the investigated topics in endometriosis…

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In vitro fertilization protocols in endometriosis patients - Pinar Kodaman, MD., PhD.

In vitro fertilization protocols in endometriosis patients - Pinar Kodaman, MD., PhD. By Hale Goksever Celik

Infertility is frequently encountered in endometriosis patients because of anatomic distortion, alterations in endometrial receptivity, diminished tubal peristalsis, and sperm movements. Even though the disease stage and presence of endometrioma is negatively correlated with infertility, it is unpredictable which women…

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Endometrioma size and anti-Müllerian hormone levels

Endometrioma size and anti-Müllerian hormone levels By Hale Goksever Celik

Endometriotic lesions are encountered in different locations in the pelvic cavity, including but not limited to the ovaries, the pouch of Douglas, the ureters, the bladder, and the bowel. Cystic endometriosis lesions located in the ovary are called "endometrioma". Endometriomas have…

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Reduced risk of "small for gestational age baby" following frozen embryo transfer in endometriosis patients

Reduced risk of By Hale Goksever Celik

Infertility is encountered frequently in patients with endometriosis. These women could be managed using assisted reproductive technology (ART) including in-vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) to achieve pregnancy. However, some adverse obstetric and perinatal outcomes are experienced more…

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Depression and anxiety levels in "in vitro fertilization" patients with endometriosis

Depression and anxiety levels in By Hale Goksever Celik

Endometriosis is a reproductive-aged and estrogen-dependent disease. The most common symptoms of this disease are dysmenorrhea, dyspareunia, chronic pelvic pain, and infertility affecting the quality of life in several aspects mainly the psychological domain. In the literature, there are many studies…

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International experts commentary for assisted fertility treatment facilities amidst COVID-19

International experts commentary for assisted fertility treatment facilities amidst COVID-19 By Nasuhi Engin Aydin

A multinational and multi-institutional commentary led by Dr. Alviggi from Italy and Dr.Esteves from Brazil has addressed important issues on assisted reproductive technology treatment amid COVID-19 lockdown suggesting remedies in the journal of "Reproductive Biology and Endocrinology" May 2020 issue.…

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New Insights on Infertility and Low Success Rates of Assisted Reproduction in Women with Endometriosis

New Insights on Infertility and Low Success Rates of Assisted Reproduction in Women with Endometriosis By Özge Özkaya

The fluid surrounding immature eggs waiting to mature and be fertilized by a sperm to lead to pregnancy is different in women with endometriosis compared to those without, according to a study published in Molecular Biology Reports. This could explain,…

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Maternal body mass index and neonatal outcomes in women with endometriosis

Maternal body mass index and neonatal outcomes in women with endometriosis By Hale Goksever Celik

Endometriosis is defined as the localization of endometrial glandular and stromal-like tissue outside the uterine cavity. Its prevalence is 10-15% in the general population of this age. However, endometriosis is diagnosed more frequently in infertile women with a prevalence of…

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The effect of endometriosis on implantation in women with endometriosis associated infertility

The effect of endometriosis on implantation in women with endometriosis associated infertility By Hale Goksever Celik

One of the most common clinical findings of women with endometriosis is fertility problems. Women with endometriosis often benefit from in vitro fertilization methods to get pregnant. However, whether there is a detrimental effect of endometriosis on in vitro fertilization outcomes…

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Which comes first in endometriosis management: In vitro fertilization or surgery?

Which comes first in endometriosis management: In vitro fertilization or surgery? By Hale Goksever Celik

Endometriosis is defined as the localization of endometrial glandular and stromal tissue outside the uterine cavity. The prevalence is found to be 7%–10%, but among infertile women, it increases up to 50%. Early diagnosis and personalized management are important to…

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ICSI Outcomes for Laparoscopic Intervention of Endometriosis

 ICSI Outcomes for Laparoscopic Intervention of Endometriosis By Kasthuri Nair

Women with endometriosis can have trouble conceiving and often turn to fertility treatments for help. Guler et al. recently published a paper in Systems Biology in Reproductive Medicine titled “The Impact of laparoscopic surgery of peritoneal endometriosis and endometrioma on…

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