Peritoneal fluid in young women with endometriosis

Peritoneal fluid in young women with endometriosis By Selma Oransay

Many blood substances are present in peritoneal fluid due to their derivation from the transudation of blood through the peritoneal surface. Ectopic endometriotic lesions can also change the medium to contribute to the definition of the local environment of the…

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Family history of endometriosis and its characteristics

 Family history of endometriosis and its characteristics By Selma Oransay

Depression and migraine are two familial disorders affected by menstrual cycle and endometriosis patients have an increased likelihood of suffering from these comorbidities. A correlation of endometriosis, migraine and depression has been already reporteed in the literature, however a link for…

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Is continuous hormonal treatment safe and healthy method for endometriotic patients?

Is continuous hormonal treatment safe and healthy method for endometriotic patients? By Selma Oransay

One of the studies related to the search for new markers in pathophysiologic causes of endometriosis is circulating microparticles and their subset "tissue factor". In response to damage, activation, or apoptosis, these microparticles are found in human plasma, urine, saliva,…

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Dienogest versus combined oral contraceptives treatment in postoperative endometriosis care

Dienogest versus combined oral contraceptives treatment in postoperative endometriosis care By Selma Oransay

Dienogest is a synthetic progestin derivative, like oral contraceptives, used to prevent endometriosis recurrence after surgery. Randomized clinical trials verified a significantly higher reduction in endometriotic lesions, clinical symptoms, and improved quality of life obtained when dienogest was given to…

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2023 MedicalConferance: Pros and cons of hormonal interventions for endometriosis - Sarah Berga, MD

2023 MedicalConferance: Pros and cons of hormonal interventions for endometriosis - Sarah Berga, MD By Bahar Yuksel

Prof. Berga, MD., who is the Chair of Ob&Gyn at Jacobs School Medicine and Biomed Sciences, presented this speech at the 2023 EFA Medical Conference. Dr. Berga explains that the primary goals of endometriosis treatment are to reduce pain and improve quality…

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What causes pelvic pain? Androgens or estrogens?

What causes pelvic pain? Androgens or estrogens? By Selma Oransay

A comparison between women and men reveals that women suffer more pelvic pain. This reality raises the possibility of the pain-relieving effect of testosterone or androgens. It would be a wise solution to investigate how androgens affect pain at different…

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Combined Birth Control Pills May Be Beneficial in Reducing Endometriosis Pain

Combined Birth Control Pills May Be Beneficial in Reducing Endometriosis Pain By Özge Özkaya

Treatment with an extended regimen of ethinylestradiol and drospirenone improves health-related quality of life, according to a new study conducted on Japanese women with painful periods or pelvic pain due to endometriosis. (Ethinylestradiol and drospirenone are medications that are widely…

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An Overview on Treatment of endometriosis

An Overview on Treatment of endometriosis By Selma Oransay

There are different guidelines by different gynecological societies for the diagnosis and treatment of endometriosis, which is an extremely complex illness.  Kalaitzopoulos and Samartzis et al. from Switzerland worked on and compared six national and two international widely used guidelines to…

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Effects of Hormonal Contraceptives on Endometriosis Pain

Effects of Hormonal Contraceptives on Endometriosis Pain By Özge Özkaya

There is no difference between the oral progestin dienogest and combined oral contraceptive pills in managing pain and increasing quality of life in women with endometriosis, according to the results of a randomized, double-blind, placebo-controlled clinical trial. However, there was…

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Pharmacological Therapy for Endometriosis Pain

Pharmacological Therapy for Endometriosis Pain By Eylül GÜN

The negative effects of endometriosis on women’s quality of life are indisputable. Women who suffer from endometriosis might have to deal with problems in many aspects such as psychological, sexual, social, and economic. Pain which is one of the most…

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Combined contraceptive pills and immune system cells in the endometriotic cyst wall

Combined contraceptive pills and immune system cells in the endometriotic cyst wall By Nasuhi Engin Aydin

Dr. Wanwisa Waiyaput and associates from Mahidol University, Bangkok, Thailand, have published their results on the immune regulatory cells of the surgically resected endometriotic cyst walls in the “Journal of Ovarian Research”. The defective immune response is believed to have…

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Women reject using hormonal drugs for endometriosis, an accelerating need for nonhormonal medications

Women reject using hormonal drugs for endometriosis, an accelerating need for nonhormonal medications By Bahar Yuksel

Although the pathophysiology of endometriosis is poorly understood, endocrine drugs are widely used for reducing inflammation and patients’ symptoms. Burla and colleagues aimed to evaluate the patients’ thoughts and expectations about the endocrine drugs which are used in the treatment…

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Postoperative long-term estro-progestin therapy for endometrioma

Postoperative long-term estro-progestin therapy for endometrioma By Selma Oransay

After the removal of ovarian endometriomas, the major concern is the high recurrence rate of symptoms and endometriotic cysts. The estimated recurrence rate of endometriomas is up to 50% at 5 years after surgery. To prevent the recurrence, postoperatively long-term…

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The peculiarity of adolescent endometriosis

The peculiarity of adolescent endometriosis By Selma Oransay

Recent studies showed the prevalence of endometriosis in adolescents with chronic cyclic or acyclic pelvic pain is about 60-70%. Moreover, all stages of endometriosis, including deeply infiltrating endometriosis can be found in this population. Gubbels et al. from the Department…

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Diagnosis and treatment algorithm for endometriosis

Diagnosis and treatment algorithm for endometriosis By Selma Oransay

Endometriosis is a chronic and progressive disease that affects 25-30% of women between 25-35years, clinicians commonly experience during their gynecologic practice. However, the diagnosis is still late or sometimes incorrect, and this creates severe health problems and worse outcomes. A…

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The efficacy of combined hormonal contraception on pelvic pain in endometriosis patients

The efficacy of combined hormonal contraception on pelvic pain in endometriosis patients By Irem Onur

Chronic pelvic pain, which is experienced by more than 33% of endometriosis patients, constitutes a significant challenge for patients and physicians. A new study that appears in the journal Human Reproduction Open has explored the prevalence of endometriosis patients with a history…

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Adolescent dysmenorrhea and future endometriosis

Adolescent dysmenorrhea and future endometriosis By Selma Oransay

Dysmenorrhoea is typically classified as primary, or secondary due to underlying pathologies like fibroids, endometriosis, adenomyosis or uterine anomalies. Generally, long-term dysmenorrhea is present in endometriotic patient's anamnesis, but until recently, the research to clarify this connection remained retrospective. Knox et…

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Endometriosis and female pelvic pain in all aspects

Endometriosis and female pelvic pain in all aspects By Hale Goksever Celik

Endometriosis is defined as the localization of endometrial glandular and stromal tissue outside the uterine cavity. The prevalence of the disease ranges between 6-10% in reproductive-aged women. However, endometriosis is more frequently encountered in women with chronic pelvic pain and…

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Endometriosis-associated pain control by contraceptive implant or intrauterine system

Endometriosis-associated pain control by contraceptive implant or intrauterine system By Hale Goksever Celik

Endometriosis is defined as the localization of endometrial glandular and stromal cells outside the uterine cavity. The most common symptoms are dysmenorrhea, dyspareunia, and chronic pelvic pain, all of which affect the quality of women’s lives. Several studies investigating the…

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Oral Contraceptives and Low-Cost Progestins to Reduce Endometriosis-Associated Pain

Oral Contraceptives and Low-Cost Progestins to Reduce Endometriosis-Associated Pain By Özge Özkaya

Most women with endometriosis-associated pain did not feel the need to use expensive progestin or undergo surgery. Instead, they were satisfied with a low-cost progestin to treat their symptoms. This is according to a study published in the journal Fertility…

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Contraceptives for the management of endometriosis pain

Contraceptives for the management of endometriosis pain By Murat Osman

Endometriosis is a common gynecologic disease that affects many women of reproductive age and is associated with significant morbidity. One of the treatment options for women with endometriosis is the use of oral contraceptives (OCPs) for pain management. However, its…

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Which Endometriosis Treatment is Better: NETA or Extended-cycle OC (Seasonique®)?

Which Endometriosis Treatment is Better: NETA or Extended-cycle OC (Seasonique®)? By Kasthuri Nair

Scala et al. recently shared the findings of their patient preference prospective study in a journal article titled “Norethindrone acetate versus extended-cycle oral contraceptive (Seasonique®) in the treatment of endometriosis symptoms: A prospective open-label comparative study,” which was published in the…

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Switching to a Low-Cost Progestin May Help Reduce Endo Pain When Oral Contraceptives Won’t Work

Switching to a Low-Cost Progestin May Help Reduce Endo Pain When Oral Contraceptives Won’t Work By Özge Özkaya

The majority of women with endometriosis-associated pain were satisfied to have switched to a treatment with norethisterone acetate or NETA, a synthetic, orally active progestin, when their oral contraceptive was ineffective, found a study published in the journal Reproductive Sciences.…

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Hormonal Contraceptives and the Risk of Breast Cancer

Hormonal Contraceptives and the Risk of Breast Cancer By Kasthuri Nair

A study titled “Contemporary Hormonal Contraception and the Risk of Breast Cancer” was recently published in The New England Journal of Medicine and was immediately picked up and summarized by many well-known newspapers and broadcasting journals, including but not limited…

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The Benefits of Vaginal Administration of Drugs

The Benefits of Vaginal Administration of Drugs By Kasthuri Nair

There are numerous methods of drug administration used by healthcare providers today. Buggio and colleagues suggest the vagina as another avenue for delivery. They recently published a paper titled "Per vaginam" topical use of hormonal drugs in women with symptomatic…

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The Most Cost Effective Medical Treatment to Prevent Recurrent Endometriosis

The Most Cost Effective Medical Treatment to Prevent Recurrent Endometriosis By Özge Özkaya

A new study conducted in China found that a class of drugs called Gonadotropin-releasing hormone agonists (GnRH-a) is more cost effective for the treatment of recurrent endometriosis despite the fact that they are more expensive than oral contraceptives. The results…

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Hormonal Contraceptives and Endometriomas

Hormonal Contraceptives and Endometriomas By Kasthuri Nair

Hormonal contraceptive has recently become a popular choice of birth control for many women. The European Journal of Obstetrics & Gynecology and Reproductive Biology recently published an article entitled “Incidence of ovarian endometrioma among women with peritoneal endometriosis with and…

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