Race, socioeconomic status, and health

Race, socioeconomic status, and health By Dr. Youngran Park

Racial disparities in health have been long noted in the United States. The differences in socioeconomic status across racial groups are a major contributor to racial disparities in health. However, race reflects multiple dimensions of social inequality. Understanding and effectively…

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Early Developmental Gene May Play a Role in Endometriosis

Early Developmental Gene May Play a Role in Endometriosis By Özge Özkaya

An early developmental gene called twist may encourage the connective tissue cells of the lining of the uterus to change from being epithelial to being mesenchymal, so-called epithelial to mesenchymal transition (EMT).  Mesenchymal cells play important roles in biological processes…

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Study Sheds Light on the Molecular Mechanism of Endometriosis Development

Study Sheds Light on the Molecular Mechanism of Endometriosis Development By Özge Özkaya

A protein called transforming growth factor-beta1 (TGF-B1) enhances the capacity of endometriotic cells or cells that make up the lining of the uterus to migrate, invade, and colonize other areas in the body. This is according to a study published…

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Conservative Surgery May Be Sufficient to Halt the Development of Deep Endometriosis

Conservative Surgery May Be Sufficient to Halt the Development of Deep Endometriosis By Özge Özkaya

Deep endometriosis develops as a result of collective cell migration and nerve recruitment from surrounding organs, suggests a study published in the scientific journal Fertility and Sterility.   Collective cell migration is the biological process whereby a group of cells moves…

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Programmed cell death 4 suppresses endometriosis by inhibiting autophagy and NF-κB/MMP2/MMP9 signal pathway

Programmed cell death 4 suppresses endometriosis by inhibiting autophagy and NF-κB/MMP2/MMP9 signal pathway By Dr. Youngran Park

Endometriosis is a kind of benign disease but shares many similar features with cancers, such as abnormal cell migration, invasion, and unrestrained growth. It has been known that some genes are expressed differentially in eutopic endometrium of EM patients compared…

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A Better Way to Diagnose Endometriosis?

A Better Way to Diagnose Endometriosis? By Özge Özkaya

Three proteins found in the blood and endometrial tissues could be used to determine the stage of endometriosis and the severity of painful periods according to a study published in the journal Current Medical Science. Evaluating the levels of these…

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Could the Sleep Hormone Treat Endometriosis?

Could the Sleep Hormone Treat Endometriosis? By Özge Özkaya

Melatonin blocks cell proliferation, invasion, and migration in both normal and endometriotic epithelial cells, according to a study published in the scientific journal Reproductive Biology and Endocrinology. Melatonin could, therefore, be a potential treatment for endometriosis  The formation and progression…

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A key cytokine in endometriosis can be targeted for endometriosis treatment

A key cytokine in endometriosis can be targeted for endometriosis treatment By Demet Candaş Green

Immune system dysfunction has been implicated in the development of endometriosis. One study showed that 95% of cells found in the peritoneal fluid of women with endometriosis are macrophages with impaired phagocytic function, which are unable to eat away unwanted…

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An Antagonist for Endometriosis Disease Progression: LINC00261

An Antagonist for Endometriosis Disease Progression: LINC00261 By Kasthuri Nair

The molecular mechanisms surrounding endometriosis remain elusive to this day. Sha et al. from Wenzhou Medical University, China, reported that LINC00261, a long non-coding RNA, may play a substantial role in inhibiting the pathogenesis of this painful illness. Their paper…

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Ping-Chong-Jiang-Ni Formula: A Natural Treatment

Ping-Chong-Jiang-Ni Formula: A Natural Treatment By Kasthuri Nair

In the world of modern medicine, natural and herbal remedies are often under utilized. Liang et al. recently published an article in Evidence-Based Complementary and Alternative Medicine where they explored the benefits of using a Chinese Herbal Medicine to treat…

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