A highly sensitive Immunohistochemical Marker for Stromal Cells in endometriosis

A highly sensitive Immunohistochemical Marker for Stromal Cells in endometriosis By Engin Aydin

Endometriosis is diagnosed histopathologically by the presence of endometrium-like tissues outside the uterus. Positive CD10 immunohistochemistry, highlighting stromal cells of the endometrium, is a useful adjunct for pathologists in the tissue diagnosis. However, CD10 expression is not specific to endometrial stromal…

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Which cell defines endometriosis?

Which cell defines endometriosis? By Murat Osman

A well-accepted theory regarding the pathogenesis of endometriosis hypothesizes that the origin of endometriosis is from peritoneal dissemination of endometrial cells and stroma during the neonatal period or menarche. Varying cellular components of endometriosis have been observed in the setting…

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Short-term effects of dienogest on ovarian endometriomas

Short-term effects of dienogest on ovarian endometriomas By Murat Osman

First-line treatment of symptomatic, uncomplicated ovarian endometriosis is the use of progestins with or without estrogens such as Dienogest (DNG). These drugs are used to inhibit ovulation and thus reduce the estrogenic environment in which endometriosis relies upon for survival.…

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