Another Genetic Polymorphism That May Increase Risk of Endo

Another Genetic Polymorphism That May Increase Risk of Endo By Özge Özkaya

A single letter change in the Epidermal Growth Factor Receptor (EGFR) gene may significantly increase the risk of endometriosis.  This is according to a study conducted among women in Southwest China and published in the journal Medicine. Identifying genetic risk…

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Polymorphisms of STAT4 gene in the pathogenesis of endometriosis

Polymorphisms of STAT4 gene in the pathogenesis of endometriosis By Dr. Youngran Park

Endometriosis is one of the most common gynecological diseases in reproductive-age women characterized by the occurrence of endometrial tissue outside the uterine cavity. Researchers have put forward numerous hypotheses to explain ectopic endometrial tissue, and the bulk of the evidence…

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Could Endometriosis-Related Infertility Be Genetic?

Could Endometriosis-Related Infertility Be Genetic? By Özge Özkaya

Researchers identified genetic polymorphisms or individual differences in two genes called AMA5 and KAZN among women with endometriosis who were infertile and control women who were fertile. The identification of these polymorphisms could help scientists better understand why some women…

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Molecular Susceptibility to Endometriosis

Molecular Susceptibility to Endometriosis By Kasthuri Nair

Fayez et al., a group of researchers from various institutions in Iran, recently published a paper in the Avicenna Journal of Medical Biotechnology titled “Arylamine N-acetyltransferase 2 Polymorphisms and the Risk of Endometriosis.” This study focused on the relationship between…

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Polymorphism of IL12B May Help Solve Endometriosis

Polymorphism of IL12B May Help Solve Endometriosis By Kasthuri Nair

Zhao et al. recently published a paper titled “A functional promoter polymorphism in interleukin 12B gene is associated with an increased risk of ovarian endometriosis” in Gene. The research group from Hebei Medical University wanted to explore the potential roles…

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Endometriosis-related Mitochondrial DNA Control Region Polymorphisms Found in Brazil

Endometriosis-related Mitochondrial DNA Control Region Polymorphisms Found in Brazil By Kasthuri Nair

The genetic basis for the formation of endometriosis is still at large. Andres et al. from the University of Sao Paulo, Brazil,  looked at various individuals, with and without endometriosis, to determine polymorphisms in the mitochondrial DNA (mtDNA) control region that…

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Combination Polymorphisms of Three "Estrogene-Related" Genes Increase the Risk of Endometriosis

Combination Polymorphisms of Three By Kasthuri Nair

Cardoso et al. recently published a paper titled “Combined Effect of the PGR +331C > T, CYP17A1 -34A > G and CYP19A1 1531G > A Polymorphisms on the Risk of Developing Endometriosis” in Revista brasileira de ginecologia e obstetrician. The…

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