Clinical Endometriosis Despite Negative Histology: A Diagnostic Dilemma
To diagnose endometriosis, clinicians typically rely on a combination of symptoms, noninvasive imaging, and histopathological examination of lesions seen during surgery. However, in some cases, even when visible lesions suggest endometriosis, histological confirmation is not obtained—leaving the diagnosis uncertain. This…
Key Points Lay SummaryThe prevalence of deep and superficial dyspareunia in women with endometriosis..
Almost half of the women affected by endometriosis experience both superficial and deep dyspareunia. While superficial dyspareunia is less studied, deep dyspareunia is often linked to mechanical pressure on endometriotic lesions or tissue rigidity. To address the sexual difficulties faced…
Key Points Lay SummaryImproving fertility in peritoneal endometriosis
Endometriosis is the most common gynecologic disease that affects 10-15% of women in their reproductive age. The causal relationship between endometriosis and infertility is not clear yet, but adhesions and anatomical distortions due to the progression of the disease are…
Key Points Lay SummarymicroRNA signatures as a non-invasive diagnostic tool for peritoneal endometriosis
Using microRNA (miRNA) signatures obtained from bodily fluids as a non-invasive diagnostic tool for endometriosis has recently emerged as a useful method. Endometriosis remains an underdiagnosed disease, especially with subtypes such as peritoneal endometriosis which presents with non-specific symptoms. Researchers…
Key Points Lay SummaryPeritoneal fluid in young women with endometriosis
Many blood substances are present in peritoneal fluid due to their derivation from the transudation of blood through the peritoneal surface. Ectopic endometriotic lesions can also change the medium to contribute to the definition of the local environment of the…
Key Points Lay SummaryThe type of surgical approach compared to complications and recurrence for colorectal endometriosis
Women with endometriosis may have extension and infiltration of the intestine, called "colorectal endometriosis, in up to 12%. The main symptoms are alterations in bowel habits, pelvic pain, and/or infertility. The gold standard management option for colorectal endometriosis is surgical…
Key Points Lay SummaryNew adapted ESHRE guidelines for endometriosis.
Eun Hee Yu and Jong Kil Joo from the Department of Obstetrics and Gynecology of Pusan National University School of Medicine, Republic of Korea, published a commentary on the 2022 ESHRE guidelines, referring to the representative changes and important updates in a recently…
Key Points Lay SummaryA review of multimodal imaging modalities for endometriosis.
Since there is a lack of non-invasive biomarkers to diagnose endometriosis clinically, imaging techniques such as transvaginal ultrasonography and MRI have significant importance in preoperative endometriosis diagnosis. These imaging techniques allow appropriate surgical planning before laparoscopic excision, especially in deeply…
Key Points Lay SummaryUltrasonographic Presurgical Staging and Classification of Endometriosis
Laparoscopic surgery is the gold standard for diagnosing endometriosis, but a preoperative imaging procedure is strongly recommended. Transvaginal sonography by a skilled examiner is not inferior to MRI diagnostics regarding sensitivity and specificity in predicting the extension of deep endometriosis. …
Key Points Lay SummaryHow Likely Am I to Conceive After Endometriosis Surgery?
Women with superficial peritoneal endometriosis and just one type of lesion are more likely to conceive after surgery, according to a new study published in the International Journal of Gynecology and Obstetrics. This is important because patients will be better…
Key Points Lay SummaryComplex Relation Between Body mass index and endometriosis
This research aimed to find the relationship between BMI and endometriosis especially related to surgical phenotype and lesion location. An observational cohort study was led by Holdsworth-Carson et al, from Australia. The article was recently published in "RBMO" . Many earlier studies report…
Key Points Lay SummaryThe improvement of fertility rate and symptoms of superficial endometriosis following laparoscopic peritoneal stripping
Pain, in the form of diverse entities, including dyspareunia, dysuria, dyschezia, is the main symptom of endometriosis patients. The severity of pain is independent of the extent and the location of the disease, and generally causes a negative impact on…
Key Points Lay SummaryLimits of endometrioma surgery in infertility patients - Liselotte Mettler, MD, PhD
The removal of endometrioma may affect ovarian reserve because healthy follicles near endometrioma could also be excised during this procedure. Another concern about the ovarian reserve is that it may be already low before the surgery. Anti Mullerian Hormone (AMH)…
Key Points Lay SummaryIndocyanine green in endometriosis surgery
Recently, indocyanine green is well studied and used safely in real-time perfusion to organs or tissues, after taking into consideration its binding capacity to the plasma proteins. The usefulness and the effectiveness of near-infrared camera guided indocyanine green is proved with…
Key Points Lay SummaryRecurrence following surgery for subtypes of endometriosis
Endometriosis is a disease identified by the location of endometrial stromal and glandular cells outside the uterine cavity. It is considered as a gynecological disease of reproductive-aged women. Three subtypes of endometriosis are peritoneal endometriosis which defines the endometriotic lesions…
Key Points Lay SummaryThe Relationship Between Dyspareunia and Infertility in Endometriosis
Wahl et al. from the Center of Pelvic Pain and Endometriosis British Columbia Women's Hospital, Vancouver, Canada studied with endometriotic patients suffering from dyspareunia who were referred to their center and built a cross-sectional study to investigate the relations between…
Key Points Lay SummaryAdiposity, endometriosis type and severity
Dr. Jiyoung from the division of Public Health, Department of Family and Preventive Medicine of the University of Utah, planned a prospective cross-sectional study to assess whether there is an inverse relationship between the adiposity and endometriosis. The results of…
Key Points Lay SummaryThe coexistence deep infiltrating endometriosis and fibromyalgia
Endometriosis is defined as the localization of endometrial glandular and stromal cells outside the uterine cavity. The main symptoms of endometriosis which are dysmenorrhea, dyspareunia, and chronic pelvic pain impair the quality of life of these women. This disease may…
Key Points Lay SummaryPreoperative factors to predict unresponsiveness in women undergoing endometriosis surgery
Endometriosis is defined as the localization of endometrial glandular and stromal cells outside the uterine cavity. Despite extensive research, the optimal management of endometriosis still remains unclear. Several treatment options include analgesic medication, hormonal treatments, and surgical intervention. There is…
Key Points Lay SummaryBuilding an ultrasonographic database for superficial endometriosis.
Chowdary et al. from University of Auckland, Australia, recently published a retrospective, small group study in Australian New Zeland Journal of Obstetrics and Gynecology, to demonstrate ultrasonographic findings of mild endometriosis patients with pelvic pain are associated with their laparoscopic diagnosis.…
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