Blood-based biomarkers for the detection of endometriosis and adenomyosis

Blood-based biomarkers for the detection of endometriosis and adenomyosis By Eylül GÜN

One of the biggest challenges in endometriosis management is the delay in diagnosis. Scientists have been trying to come up with biomarkers to detect it quicker. Thinking blood-based biomarkers could aid in earlier diagnosis and help with the duly administration…

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Do not underestimate the power of red blood cell evaluation in endometriosis

Do not underestimate the power of red blood cell evaluation in endometriosis By Eylül GÜN

In an effort to develop an easy-to-use diagnostic marker, research has focused on the pro-inflammatory nature of endometriosis and the raised levels of inflammatory markers. The neutrophil-to-lymphocyte ratio (NLR) has emerged as one of these markers. Moreover, endometriosis has been…

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Body Mass Index and indicators of metabolic syndrome in women with Endometriosis

Body Mass Index and indicators of metabolic syndrome in women with Endometriosis By Hale Goksever Celik

Endometriosis is a disease of reproductive-aged women and has common pathophysiological mechanisms with other chronic health morbidities due to its estrogen-dependent chronic inflammatory background. The changes in the inflammatory components of adipose tissue may have an impact on the quality of…

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Best practice: How to reduce intraoperative bleeding?

Best practice: How to reduce intraoperative bleeding? By Selma Oransay

Although laparoscopic hysterectomy is a popular and common approach for removing benign uterine lesions, some technical steps especially concerning uterine artery closure depend on the surgeon's preference. Uterine artery ligation may be performed either at the uterus level, which is common…

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Selected Blood Inflammatory Biomarkers May Help Identify Endometriosis

Selected Blood Inflammatory Biomarkers May Help Identify Endometriosis By Özge Özkaya

Levels of inflammatory biomarkers in the blood differ between women with endometriosis and those without the disease. Levels of some biomarkers also differ according to the stage of endometriosis. This is according to a new study by Polish scientists published…

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New Signaling Pathway Could Be Crucial in the Development of Endometriosis

New Signaling Pathway Could Be Crucial in the Development of Endometriosis By Özge Özkaya

RAMP1 signaling is crucial for growth and blood and lymphatic vessel formation in endometrial tissue, according to a new study published in the Journal of Cellular and Molecular Medicine. This suggests that blocking RAMP1 could be a new way to…

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Hemorrhagic Ascites, Belly-Blood: The cause may be endometriosis!

Hemorrhagic Ascites, Belly-Blood: The cause may be endometriosis! By Timur Seckin

A paper on the presentation of hemorrhagic ascites in endometriosis patients, written by Bernard et al. from the United States and China, was published in the journal Fertility and Sterility. From 1978 to 2016, the authors found only 37 articles, which describe 42…

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The association of significant hemoperitoneum (blood in the abdominal cavity) and deep pelvic endometriosis

The association of significant hemoperitoneum (blood in the abdominal cavity) and deep pelvic endometriosis By Irem Onur

 Although there are several theories to explain the etiology of deep endometriosis, the cause is unknown and there are currently no effective strategies to prevent its development. Bean E. et al., from University College London Hospital, UK,  observed that some…

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Menstrual blood-derived stem cells

Menstrual blood-derived stem cells By Selma Oransay

Chen et al.  from the Center of Diagnosis and Treatment of İnfectious Disease, Zhejiang University, China penned this recent review in the Journal of Stem Cell Research Therapy which is presenting the clinical potential of MenSCs (Menstrual blood-derived stem cells). …

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Development of Less Invasive Diagnostic Tests for Endometriosis Through Proteomics

Development of Less Invasive Diagnostic Tests for Endometriosis Through Proteomics By Murat Osman

Proteomics is a field which utilizes various methods to carry out large-scale studies of proteins. Due to the inherent nature of the field, proteomics focuses on the identification, localization, and functional analysis of the protein make-up of a given type…

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Could Endometriosis Be Caused by Bacteria?

Could Endometriosis Be Caused by Bacteria? By Özge Özkaya

A new concept called the bacterial contamination hypothesis in endometriosis has been proposed for the first time by researchers in Japan. This means that new potential therapies approaches could exist for this condition in addition to the conventional estrogen-suppressing therapies.…

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EFA Medical Conference 2017: "Cells Are the New Cure" Presentation by Dr. Max Gomez

EFA Medical Conference 2017: By Kasthuri Nair

Dr. Max Gomez is an award-winning broadcast journalist, CBS News Medical Correspondent, and a presenter at the EFA 2017 Medical Conference. Dr. Gomez’s presentation was titled “Cells Are the New Cure: The Cutting-Edge Medical Breakthroughs That Are Transforming Our Health.”…

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Reduced vascularization in ovarian endometriomas associated with less pain

Reduced vascularization in ovarian endometriomas associated with less pain By Yu Yu

Angiogenesis, i.e., the development of new blood vessels is believed to play an important role in endometriosis pathogenesis and symptoms. Endometriosis is associated and requires neovascularization to proliferate, invade surrounding normal structure in order to establish an endometriotic lesion. Ovarian…

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The Involvement of the Blood Clotting System in Endometriosis

The Involvement of the Blood Clotting System in Endometriosis By Özge Özkaya

The blood clotting system might be over-active in women with endometriosis, found a study published in the scientific journal Reproductive Sciences.  Although the authors stated that there is not enough evidence to suggest that over-coagulation may be directly causing endometriosis…

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Agents Causing Red Blood Cell Lysis Worsens Endometriosis

Agents Causing Red Blood Cell Lysis Worsens Endometriosis By Kasthuri Nair

Endometriosis is a painful disease characterized by inflammation and the presence of pro-oxidation factors. These pro-oxidation factors are also released when red blood cells (RBCs) lyse. A paper titled “Dapsone hydroxylamine-mediated alterations in human red blood cells from endometriotic patients”…

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