Sexual activity during menstruation: Any impact on endometriosis development?
Retrograde menstruation is among the theories for the etiology of endometriosis and there is a hypothesis that sexual activity during menstruation could potentially increase retrograde menstruation, leading to the implantation of endometrial tissue in other areas and consequently increasing the…
Key Points Lay SummaryWhy Do Some Women Develop Endometriosis While Other Don’t?
Chemotaxis by natural killer cells as well as cytotoxicity is significantly decreased in the peritoneal cavity of women with endometriosis, according to a new study published in the American Journal of Reproductive Immunology. This means that antigens that enter the…
Key Points Lay SummaryEndometriotic mesenchymal stem cells may promote endometriosis
The cause of endometriosis is still debatable. Many researchers have accepted that retrograde menstruation, where the endometrial fragments released during menstruation attach and colonize the ectopic locations, is the most plausible reason. However, the numbers just do not add up.…
Key Points Lay SummaryFallopian tubes and endometriosis
There are multiple theories to explain the pathogenesis of endometriosis, among which the most popular one is Sampson's retrograde menstruation theory. The role of endometrial stem cells/progenitors are widely studied to support the origin of ectopic lesions in recent decades.…
Key Points Lay SummaryEndometriosis by Race
Endometriosis is usually diagnosed in reproductive-aged women with an incidence of approximately 10%. The most common presenting symptoms are dysmenorrhea, dyspareunia, chronic pelvic pain, and infertility in patients with endometriosis. Some risk factors have been identified for the development of…
Key Points Lay SummaryDefective “ferroptosis”: a new pathogenetic explanation of endometriosis
Dr. Ng and associates from Tufts University School of Medicine, Boston, USA made a comprehensive review of the role of the iron element in the development of endometriotic lesions. Though iron element is essential for cell survival, and its deficiency is important…
Key Points Lay SummaryEndometrial single cells to contribute preexisting endometriosis.
Endometriosis is an estrogen-dependent inflammatory disease. This disease affects approximately 10% of reproductive-aged women and 20% to 50% of infertile women. Multiple hypotheses have been proposed for the origin of endometriosis. Retrograde menstruation is believed to take part by the…
Key Points Lay SummaryA Brief Review of Endometriosis
Endometriosis is a common disease among women of reproductive age. It is more frequently seen among women without prior pregnancies, women with a family history of endometriosis, and women with abnormal menstrual periods. Peiris et al., researchers from the United…
Key Points Lay SummaryMenstrual Effluent Can Change the Future of Endometriosis
During Endometriosis Awareness Month, Warren et al. published a paper entitled “Analysis of menstrual effluent: diagnostic potential for endometriosis” in Molecular Medicine. This paper relies heavily on the theory of retrograde menstruation, where menstrual effluent flows into the peritoneal cavity.…
Key Points Lay Summary