Inside to outside or from outside to inside?

Inside to outside or from outside to inside? By Engin Aydin

Pathogenesis of "adenomyosis", presence of the ectopic endometrium tissue within the uterine muscles, has largely been classically based on origin from basalis endometrium. Khan and associates from Japan have published their new conceptual findings on adenomyosis in Reproductive BioMedicine Online. In…

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Endometriosis in adolescents

Endometriosis in adolescents By Irem Onur

Dr. Mama S. T. from Cooper University Hospital, Camden, New Jersey, USA, recently has published his review on advances in the management of endometriosis in the adolescent in the journal “Current Opinion Obstetrics and Gynecology”. In adolescence, there is a…

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New Target for Endometriosis Treatment?

New Target for Endometriosis Treatment? By Özge Özkaya

NR4A1 could be a novel target for the treatment of endometriosis, according to a study published in the scientific journal Cell Physiology and Biochemistry. NR4A1 is a receptor protein involved in cell division, inflammation, and programmed cell death. The development…

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Exosomal miR-214 from endometrial stromal cells inhibits endometriosis fibrosis.

Exosomal miR-214 from endometrial stromal cells inhibits endometriosis fibrosis. By Dr. Youngran Park

Fibrosis is an important pathological feature of endometriosis. Novel therapies targeting the mechanisms of fibrosis in endometriosis are indispensable for the development of strategies to prevent and treat endometriosis. Previous microarray studies have detected some miRNAs that are aberrantly expressed…

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Endometriosis and its pro-fibrotic nature. 

Endometriosis and its pro-fibrotic nature.  By Dr. Youngran Park

Endometriosis is currently defined as the presence of endometrial epithelial and stromal cells at ectopic sites. However, with advances in disease knowledge, several vital issues challenge this old definition. Especially, endometrial stromal and glands have been shown to represent only…

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Which cell defines endometriosis?

Which cell defines endometriosis? By Murat Osman

A well-accepted theory regarding the pathogenesis of endometriosis hypothesizes that the origin of endometriosis is from peritoneal dissemination of endometrial cells and stroma during the neonatal period or menarche. Varying cellular components of endometriosis have been observed in the setting…

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Characteristics of Ovarian Endometriotic Cysts Could Help Determine Whether Endometrioma Will Reoccur

Characteristics of Ovarian Endometriotic Cysts Could Help Determine Whether Endometrioma Will Reoccur By Özge Özkaya

The features of ovarian endometriotic cysts could help predict whether endometrioma will re-occur in individual patients, according to a study published in the European Journal of Obstetrics and Gynecology. Predicting the risk of recurrence is important because it can help…

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