By Bahar YukselResveratrol for endometriosis
By Bahar Yuksel
Endometriosis has been studied previously about its inflammatory nature and its tendency for causing macrophage disfunction. In the study conducted by Chunyan Wang et al, the researchers analyzed the effect of a flavonoid, "resveratrol" on endometriosis lesions and the mechanism…
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By Hale Goksever CelikVitamin D supplementation, endometriosis symptoms and metabolic profiles
By Hale Goksever Celik
Patients with endometriosis suffer from dysmenorrhea, dyspareunia, chronic pelvic pain, and infertility. These women are also at higher risk for ovarian and breast cancer, cardiovascular events, and metabolic abnormalities. Several medical and surgical alternatives have been recommended to these patients…
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By Selma OransayAntioxidant therapy for the endometriosis pain
By Selma Oransay
Ts the protective defense mechanism of cells, hence the destruction of balance between oxidants and antioxidants in our body is called "redox imbalance". The major oxidants are reactive oxygen species (ROS) that are involved in multiple cellular processes by physiologically…
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Can a grape ingredient, resveratrol, be the promised warrior to defeat endometriosis?
By Bahar Yuksel
Endometriosis is a chronic estrogen-dependent disorder and has a known relationship with angiogenesis, inflammation, and oxidative stress. Resveratrol is a part of a "polyphenol" compound which are thought to act like antioxidants, protects the body against damage. This compound is normally…
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By Nadire DuruAntioxidants inhibit autophagy in ectopic endometrial cells
By Nadire Duru
Factors involved in the development of ectopic endometrium are not well-known, but several reports demonstrate a potential role for the pathophysiological processes including autophagy. Studies show that autophagy plays a significant role in endometriosis but the key mechanisms underlying the…
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By Nasuhi Engin AydinEndometriosis and infertility: current concepts
By Nasuhi Engin Aydin
Hungarian and US scientists have published a comprehensive review on infertility related to endometriosis in Frontiers in Endocrinology, November 2018 issue. Endometriosis is a common entity in women of reproductive age which often leads to infertility. Compiled research data reveal…
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Vitamin C supplementation in the patients with endometriosis undergoing in vitro fertilization-embryo transfer
By Hale Goksever Celik
Endometriosis is defined as the localization of endometrial stromal and glandular cells outside the uterine cavity. Women having endometriosis present with dysmenorrhea, dyspareunia, chronic pelvic pain, and infertility. Thus, infertility remains a significant problem for women with endometriosis. Endometriosis is…
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By Yu YuTherapeutic potential of ginseng based compound in preclinical models of endometriosis
By Yu Yu
Currently, the drug option for women with endometriosis mainly focus on reducing estrogens levels (e.g., progestins, androgens, gonadotropin-releasing hormone (GnRH) agonists, and aromatase inhibitors). However, these therapies can have low effectiveness with frequent recurrence and considerable side effects. Therefore, there…
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By Dr. Youngran Park3,6-DHF suppresses the invasive properties of endometrial stromal cells through the Notch signaling
By Dr. Youngran Park
Dr. Zhou group reported recently that 3,6-DHF can inhibit the development of EMT, migration, and invasion of endometrial stromal cells by inhibiting the Notch signaling pathway. Endometriosis is a condition in which the layer of tissue (glands and mesenchyme) that normally…
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