Enhanced local and systemic inflammatory cytokine mRNA expression in women with endometriosis 

Enhanced local and systemic inflammatory cytokine mRNA expression in women with endometriosis  By Ellen Tumimbang

Endometriosis is not only characterized by the implantation of endometriotic tissue outside of the uterine cavity but also necessitates an impaired immune response. It is suggested that abnormal immunological mechanisms causing the dysfunction of immune cells and their mediators are…

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CD4, CD8 T lymphocytes gain importance in endometriosis

CD4, CD8 T lymphocytes gain importance in endometriosis By Nasuhi Engin Aydin

Immune dysregulation is important in the development of endometriosis where the role of various lymphocyte subpopulations has been investigated up till now. Caihua Li and associates from Anhui Medical University, China, made a unique observation regarding CD4 and CD8 T…

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Programmed cell death 4 suppresses endometriosis by inhibiting autophagy and NF-κB/MMP2/MMP9 signal pathway

Programmed cell death 4 suppresses endometriosis by inhibiting autophagy and NF-κB/MMP2/MMP9 signal pathway By Dr. Youngran Park

Endometriosis is a kind of benign disease but shares many similar features with cancers, such as abnormal cell migration, invasion, and unrestrained growth. It has been known that some genes are expressed differentially in eutopic endometrium of EM patients compared…

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Immune Response in Endometriosis and Regulatory T cells

Immune Response in Endometriosis and Regulatory T cells By Yu Yu

The adaptive immune system is crucial for many diseases. Lymphocytes, including T cells, are particularly important in the adaptive immune system. Previous research suggested that defective immune response could play a role in endometriosis. The hypothesis proposes that the immune…

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