Cancer-associated mutations and endometriosis

Cancer-associated mutations and endometriosis By Ellen Tumimbang

Endometriosis is thought to benign gynecological disease. However, recent studies compiled in this review paper suggest that spontaneous somatic mutations are driven to occur during the cyclic bleeding resulting in endometriosis tissue undergoing repeated tissue injury and repair. Mutations are…

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New findings in adenomyosis (endometriosis interna) patients with potential theraupetic research implications

New findings in adenomyosis (endometriosis interna) patients with potential theraupetic research implications By Nasuhi Engin Aydin

Xue Shen and associates from Beijing, China have published their observations related to cannabinoid receptors, i.e., CB1 and CB2, in patients with adenomyosis, recently in the journal  "Biomed Research International".  Adenomyosis is an estrogen-dependent uterine disorder where a nonmalignant invasion…

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Four cases of endometrioid borderline ovarian tumour: case reports and literature review

Four cases of endometrioid borderline ovarian tumour: case reports and literature review By Nasuhi Engin Aydin

Physicians from Kyoto University Graduate School of Medicine, Kyoto, Japan, report four cases of ovarian EBTs and a review literature in a recently published manuscript at British Medical Journal, case reports. Endometrioid borderline tumors (EBTs) of the ovary are uncommon…

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Therapeutic potential of ginseng based compound in preclinical models of endometriosis

Therapeutic potential of ginseng based compound in preclinical models of endometriosis By Yu Yu

Currently, the drug option for women with endometriosis mainly focus on reducing estrogens levels (e.g., progestins, androgens, gonadotropin-releasing hormone (GnRH) agonists, and aromatase inhibitors). However, these therapies can have low effectiveness with frequent recurrence and considerable side effects. Therefore, there…

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Benign Gynecological Tumors in Women with Endometriosis

Benign Gynecological Tumors in Women with Endometriosis By Kasthuri Nair

Matalliotaki et al. recently published a paper titled “Coexistence of benign gynecological tumors with endometriosis in a group of 1,000 women” in Oncology Letters. The study had two main objectives. The first goal was to understand the link between endometriosis…

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Diseases that Coexist with Adenomyosis and Endometriosis

Diseases that Coexist with Adenomyosis and Endometriosis By Kasthuri Nair

Adenomyosis, defined by endometrial glands and stroma found within the muscular uterine wall, and endometriosis are two common gynecological diseases that are similar pathologically and symptomatically. Choi et al. recently conducted a study where they hoped to determine the prevalence…

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EFA Medical Conference 2017: "Breast Cancer in Young Women; Early Diagnosis Timely Intervention" Presentation by Dr. Stephanie Bernik

EFA Medical Conference 2017: By Kasthuri Nair

Dr. Stephanie Bernik is the Chief of Surgical Oncology of Surgery and General Surgery at the Lenox Hill Hospital. She recently presented at the EFA 2017 Medical Conference, and her presentation was titled “Breast Cancer in Young Women; Early Diagnosis…

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The Role of Natural Killer Cells in the Development of Endometriosis Unravelled

The Role of Natural Killer Cells in the Development of Endometriosis Unravelled By Özge Özkaya

Specialized immune cells called natural killer cells found in the peritoneal fluid of women with severe endometriosis may facilitate the development of the disease, according to a study published in the American Journal of Reproductive Immunology.   This finding could help…

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Endometriosis Does Not Increase Overall Risk of Breast Cancer, Study Finds

Endometriosis Does Not Increase Overall Risk of Breast Cancer, Study Finds By Özge Özkaya

Endometriosis is not associated with the overall risk of breast cancer, according to a study published in the journal Obstetrics & Gynecology.  The condition may, however, be significantly associated with an increased risk of breast tumors that express estrogen receptors (ER)…

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