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Clinical Endometriosis Despite Negative Histology: A Diagnostic Dilemma

Clinical Endometriosis Despite Negative Histology: A Diagnostic Dilemma By Selma Oransay

To diagnose endometriosis, clinicians typically rely on a combination of symptoms, noninvasive imaging, and histopathological examination of lesions seen during surgery. However, in some cases, even when visible lesions suggest endometriosis, histological confirmation is not obtained—leaving the diagnosis uncertain. This…

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Dysregulated Metabolomic Signatures of Young Patients With Endometriosis

Dysregulated Metabolomic Signatures of Young Patients With Endometriosis By Özge Özkaya

A new study published in Human Reproduction reveals that adolescents and young adults with endometriosis exhibit significant dysregulation in their plasma metabolomic profiles. In particular, fatty acyls and ceramides were found to be elevated in patients with endometriosis compared to…

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Psychological and Clinical Impact of Adolescent Endometriosis

Psychological and Clinical Impact of Adolescent Endometriosis By Selma Oransay

Alarmingly, two-thirds of individuals with endometriosis report symptom onset before the age of 20, underscoring the importance of timely recognition and intervention for adolescent endometriosis. In adolescent age group, severe menstrual pain is the most common symptom, often interfering with…

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Having Endometriosis Surgery After IVF Better, Study Suggests

Having Endometriosis Surgery After IVF Better, Study Suggests By Özge Özkaya

A new study published in Archives of Gynecology and Obstetrics suggests that performing in vitro fertilization (IVF) before surgery may lead to better IVF outcomes for women with endometrioma. To determine the optimal treatment sequence, Dr. Ivan Sini and colleagues from…

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The Endometrium Speaks: Inflammatory Clues to Peritoneal Endometriosis

The Endometrium Speaks: Inflammatory Clues to Peritoneal Endometriosis By Nasuhi Engin Aydin

A prospective study conducted in Krakow, Poland, and recently published in BMC Women’s Health, explored the potential link between pelvic peritoneal endometriosis and chronic endometritis—a persistent inflammation of the uterine lining that may affect fertility. As endometriosis is a chronic,…

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Quality of Life in Patients with Urinary Tract Endometriosis

Quality of Life in Patients with Urinary Tract Endometriosis By Hale Goksever Celik

Urinary tract endometriosis (UTE) is a specific form of endometriosis that affects the urinary system, most commonly the bladder or urethra. It can cause symptoms such as bladder irritation, urinary urgency, painful urination (dysuria), blood in the urine (hematuria), and loin…

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Symptom Improvement After Laparoscopic Treatment of Bladder Endometriosis

Symptom Improvement After Laparoscopic Treatment of Bladder Endometriosis By Nasuhi Engin Aydin

Dr.Piriyev and associates from the Academic Hospital Weyertal, a Level III Endometriosis Center of Excellence in Germany, recently shared their experience with bladder endometriosis in the journal Diagnostics. Endometriosis, a disease affecting millions of women worldwide, can also involve distant…

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From Probe to Procedure: UBESS Enhances Preoperative Planning

From Probe to Procedure: UBESS Enhances Preoperative Planning By Selma Oransay

A new ultrasound-based system called UBESS (Ultrasound-Based Endometriosis Staging System) is designed to help surgeons estimate how complex endometriosis surgery might be before it happens. This system is used during a routine transvaginal ultrasound and classifies patients into three stages…

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Could sexual activity during menses be a risk factor in endometriosis?

Could sexual activity during menses be a risk factor in endometriosis? By Nasuhi Engin Aydin

Italian researchers recently published a literature review in Women’s Health exploring the potential role of endometriosis and menstrual sexual activity. The retrograde menstruation theory, first proposed in the early 20th century, remains a popular hypothesis suggesting that menstrual debris contribute to the…

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Diaphragma central tendon and catamenial pneumothorax

Diaphragma central tendon and catamenial pneumothorax By Selma Oransay

Endometriosis typically involves ectopic endometrial tissue in pelvic organs, such as the bladder, ovaries, and uterine ligaments, leading to symptoms like dysmenorrhea, dyspareunia, and dyschezia. A rare form occurs in the diaphragm, causing catamenial pneumothorax. Management often includes hormone therapy…

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