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Impact of Endometriosis Subtypes on Increased Ovarian Cancer Risk
The risk of ovarian cancer is markedly increased in patients with ovarian endometriomas and/or deep infiltrating endometriosis (DIE), according to a new study published in The Journal of the American Medical Association. These patients should be offered counseling about the risk of ovarian cancer and…
Key Points Lay SummaryEndometriosis and musculoskeletal function of pelvic loin complex
Endometriosis is an inflammatory and estrogen-dependent disease which is diagnosed in reproductive-aged women most frequently. These women present with a broad clinical spectrum including pelvic pain, dysmenorrhea, dyspareunia and infertility. All of these symptoms and signs may harm women’s lives…
Key Points Lay SummaryThe role of coagulation factors and tumor markers in diagnosing advanced stage endometriosis
As a systemic inflammatory condition, endometriosis features elevated proinflammatory cytokines, causing pain, endothelial dysfunction, carcinogenesis, and a hypercoagulable state. Patients with endometriosis show decreased thrombin time (TT) and activated partial thromboplastin time (APTT), alongside increased tissue factor (TF) and fibrinogen…
Key Points Lay SummaryRare but clinically important diagnosis; Herlyn-Werner-Wunderlich syndrome
The staff of the Department of Ultrasonography, Third Xiangya Hospital Central South University, Hunan, China have published their case series of the rare Herlyn-Werner-Wunderlich syndrome (HWWS) in a recent issue of Reproductive Sciences. HWWS, is a rare genital tract anomaly…
Key Points Lay SummaryAn often overlooked symptom: Sleep disorders in patients with endometriosis
Recent reports suggested that women with endometriosis have more frequent complaints of poor sleep, reduced quality of life, and higher pain scores when compared with healthy women. Patients experience fatigue and increased pain the day after insomnia. For this reason,…
Key Points Lay SummaryEndometrial cancer risk in endometriosis: What does the real-world data reveal?
Endometriosis is considered a benign disease, however, studies showed certain somatic mutations in the endometriotic glands indicating a potential link to endometrial cancer. Later, eutopic endometrial tissue was demonstrated to have the same somatic mutations. This resulted in controversial findings…
Key Points Lay SummaryEndometriosis relief: How vitamins C and E can make a difference
Recent studies indicate that oxidative stress significantly contributes to the onset and progression of endometriosis. High levels of reactive oxygen species (ROS) can cause cellular damage and enhance inflammation, leading to the pain associated with the condition. Antioxidants like vitamins…
Key Points Lay SummaryEndometriosis and mental health disorders: How associated are they?
As with any chronic condition, endometriosis does not only present with physiological problems. The association between endometriosis and mental health issues has been widely studied and it is now known that these patients undergo depression, anxiety, and even bipolar disorder…
Key Points Lay SummaryAny link between endometriosis and neonatal uterine bleeding?
A Medline search using the keywords " neonatal uterine bleeding," " pathophysiology," and "premenarche" was made by Dr. Habiba et al. from the Department of Health Sciences, University of Leicester, Leicester, UK. A total of 2264 articles were collected, and…
Key Points Lay SummaryChronic pelvic pain mechanisms in endometriosis
M. J. Quinn from Shanghai, China wrote an editorial piece in the latest issue of the American Journal of Obstetrics & Gynecology commenting on an article by Gete et al. in which they shared the findings from the Australian Longitudinal Study…
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