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Clinical Endometriosis Despite Negative Histology: A Diagnostic Dilemma
To diagnose endometriosis, clinicians typically rely on a combination of symptoms, noninvasive imaging, and histopathological examination of lesions seen during surgery. However, in some cases, even when visible lesions suggest endometriosis, histological confirmation is not obtained—leaving the diagnosis uncertain. This…
Key Points Lay SummaryDysregulated Metabolomic Signatures of Young Patients With Endometriosis
A new study published in Human Reproduction reveals that adolescents and young adults with endometriosis exhibit significant dysregulation in their plasma metabolomic profiles. In particular, fatty acyls and ceramides were found to be elevated in patients with endometriosis compared to…
Key Points Lay SummaryPsychological and Clinical Impact of Adolescent Endometriosis
Alarmingly, two-thirds of individuals with endometriosis report symptom onset before the age of 20, underscoring the importance of timely recognition and intervention for adolescent endometriosis. In adolescent age group, severe menstrual pain is the most common symptom, often interfering with…
Key Points Lay SummaryHaving Endometriosis Surgery After IVF Better, Study Suggests
A new study published in Archives of Gynecology and Obstetrics suggests that performing in vitro fertilization (IVF) before surgery may lead to better IVF outcomes for women with endometrioma. To determine the optimal treatment sequence, Dr. Ivan Sini and colleagues from…
Key Points Lay SummaryThe Endometrium Speaks: Inflammatory Clues to Peritoneal Endometriosis
A prospective study conducted in Krakow, Poland, and recently published in BMC Women’s Health, explored the potential link between pelvic peritoneal endometriosis and chronic endometritis—a persistent inflammation of the uterine lining that may affect fertility. As endometriosis is a chronic,…
Key Points Lay SummaryQuality of Life in Patients with Urinary Tract Endometriosis
Urinary tract endometriosis (UTE) is a specific form of endometriosis that affects the urinary system, most commonly the bladder or urethra. It can cause symptoms such as bladder irritation, urinary urgency, painful urination (dysuria), blood in the urine (hematuria), and loin…
Key Points Lay SummarySymptom Improvement After Laparoscopic Treatment of Bladder Endometriosis
Dr.Piriyev and associates from the Academic Hospital Weyertal, a Level III Endometriosis Center of Excellence in Germany, recently shared their experience with bladder endometriosis in the journal Diagnostics. Endometriosis, a disease affecting millions of women worldwide, can also involve distant…
Key Points Lay SummaryFrom Probe to Procedure: UBESS Enhances Preoperative Planning
A new ultrasound-based system called UBESS (Ultrasound-Based Endometriosis Staging System) is designed to help surgeons estimate how complex endometriosis surgery might be before it happens. This system is used during a routine transvaginal ultrasound and classifies patients into three stages…
Key Points Lay SummaryCould sexual activity during menses be a risk factor in endometriosis?
Italian researchers recently published a literature review in Women’s Health exploring the potential role of endometriosis and menstrual sexual activity. The retrograde menstruation theory, first proposed in the early 20th century, remains a popular hypothesis suggesting that menstrual debris contribute to the…
Key Points Lay SummaryDiaphragma central tendon and catamenial pneumothorax
Endometriosis typically involves ectopic endometrial tissue in pelvic organs, such as the bladder, ovaries, and uterine ligaments, leading to symptoms like dysmenorrhea, dyspareunia, and dyschezia. A rare form occurs in the diaphragm, causing catamenial pneumothorax. Management often includes hormone therapy…
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