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By Özge ÖzkayaThe Cognitive-Emotional Pain Network in Endometriosis
By Özge Özkaya
Pain intensity and pain-related functional burden may contribute to progressive worsening of cognitive fusion, depressive symptoms, and somatization in women with endometriosis, according to a study led by David Skvarc and published in the British Journal of Health Psychology. Cognitive-emotional…
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By Ayse AyhanRethinking Ground Truth in Endometriosis "AI"
By Ayse Ayhan
Artificial intelligence (AI) is increasingly being explored as a tool to improve the diagnosis of endometriosis, a disease that remains difficult to identify accurately and often requires years before confirmation. However, a new commentary published in Human Reproduction by Alison…
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Plant Sterol Against Endometriosis
By Özge Özkaya
Endometriosis may include an aggressive, immunomodulatory subtype driven by a cellular senescence–PAK4–AKT signaling circuit, according to a new study published in Aging Cell by Jingchun Liu and colleagues from Wuhan University. The researchers also identified the natural plant sterol stigmasterol…
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Menstural Blood: A Medium Full of Information for Reproductive Diseases
By Özge Özkaya
A study published in ImmunoHorizons by Dr. April Rees and colleagues from Swansea University Medical School, UK, demonstrates that menstrual blood provides a biologically informative and non-invasive window into immune processes underlying reproductive diseases. Using an optimized high-dimensional,27-color flow cytometry platform…
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Nerve Preservation Improves Outcomes in Bowel Endometriosis
By Özge Özkaya
Laparoscopic nerve-sparing resection (LscPR) may offer an optimal balance between effectiveness and safety in the surgical management of bowel endometriosis, according to a study published in the International Journal of Women’s Health. In a retrospective cohort of 320 women treated…
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AI-Derived Biomarkers in Endometriosis
By Ayse Ayhan
Diagnosing endometriosis remains a major challenge, often requiring invasive procedures and long delays before confirmation. A study published in Journal of Reproductive Immunology, lead by Huo and Chen from China explores whether gene expression patterns and immune cell changes in the…
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By Hale Goksever CelikLactoferrin as a Non-Hormonal Option in Endometriosis
By Hale Goksever Celik
Current treatments for endometriosis largely rely on hormonal suppression, which can limit fertility and is often associated with recurrence after discontinuation. A review published in Journal of Reproductive Sciences by Nakamura, Tanaka, and colleagues from Shiga University of Medical Science, Japan,…
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Uterine Contractility and Endometriosis
By Ayse Ayhan
Uterine contractility—the rhythmic movement of the uterus—is increasingly recognized as a key physiological process that extends beyond menstruation to influence fertility and reproductive health. A recent review from Dr. Nicoli, from Bari, Italy, highlights how these coordinated contractions, which vary…
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Biomarkers, Imaging, and AI Drive a New Era in Endometriosis Diagnosis
By Hale Goksever Celik
Endometriosis remains a chronic condition with substantial diagnostic delay, largely due to continued reliance on invasive laparoscopy despite its limitations. In a narrative review published in the International Journal of Gynecology and Obstetrics, Cosgriff et al. from USA summarize a…
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Advanced Transvaginal Ultrasound for Endometriosis Mapping
By Ayse Ayhan
Delayed diagnosis and incomplete disease mapping remain major challenges in the management of endometriosis, often contributing to prolonged symptoms and complex surgical outcomes. Improving preoperative identification of lesion location and disease extent is therefore critical for individualized treatment planning. In…
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