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By Özge ÖzkayaThe Cognitive-Emotional Pain Network in Endometriosis
By Özge Özkaya
Pain intensity and pain-related functional burden may contribute to progressive worsening of cognitive fusion, depressive symptoms, and somatization in women with endometriosis, according to a study led by David Skvarc and published in the British Journal of Health Psychology. Cognitive-emotional…
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By Ayse AyhanCan We Predict Surgical Pain Outcomes?
By Ayse Ayhan
Women with endometriosis often undergo surgery to relieve pelvic pain, yet many continue to experience persistent or recurrent symptoms even after technically successful procedures. In a new study published in PAIN, Dr. Dwayne R. Tucker and colleagues from the…
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Rethinking Ground Truth in Endometriosis "AI"
By Ayse Ayhan
Artificial intelligence (AI) is increasingly being explored as a tool to improve the diagnosis of endometriosis, a disease that remains difficult to identify accurately and often requires years before confirmation. However, a new commentary published in Human Reproduction by Alison…
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Plant Sterol Against Endometriosis
By Özge Özkaya
Endometriosis may include an aggressive, immunomodulatory subtype driven by a cellular senescence–PAK4–AKT signaling circuit, according to a new study published in Aging Cell by Jingchun Liu and colleagues from Wuhan University. The researchers also identified the natural plant sterol stigmasterol…
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Serologic Signals of Nerve Injury in Endometriosis
By Özge Özkaya
Patients with fibromyalgia demonstrated serologic evidence of ongoing neuronal injury comparable to small fibre neuropathy, according to a new study published in Pain Reports. The study also showed that patients with endometriosis exhibited an intermediate neurofilament light chain (NfL) profile,…
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Menstural Blood: A Medium Full of Information for Reproductive Diseases
By Özge Özkaya
A study published in ImmunoHorizons by Dr. April Rees and colleagues from Swansea University Medical School, UK, demonstrates that menstrual blood provides a biologically informative and non-invasive window into immune processes underlying reproductive diseases. Using an optimized high-dimensional,27-color flow cytometry platform…
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Nerve Preservation Improves Outcomes in Bowel Endometriosis
By Özge Özkaya
Laparoscopic nerve-sparing resection (LscPR) may offer an optimal balance between effectiveness and safety in the surgical management of bowel endometriosis, according to a study published in the International Journal of Women’s Health. In a retrospective cohort of 320 women treated…
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AI-Derived Biomarkers in Endometriosis
By Ayse Ayhan
Diagnosing endometriosis remains a major challenge, often requiring invasive procedures and long delays before confirmation. A study published in Journal of Reproductive Immunology, lead by Huo and Chen from China explores whether gene expression patterns and immune cell changes in the…
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By Hale Goksever CelikLactoferrin as a Non-Hormonal Option in Endometriosis
By Hale Goksever Celik
Current treatments for endometriosis largely rely on hormonal suppression, which can limit fertility and is often associated with recurrence after discontinuation. A review published in Journal of Reproductive Sciences by Nakamura, Tanaka, and colleagues from Shiga University of Medical Science, Japan,…
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Blood Based Multi-Omics Endometriosis Detection
By Hale Goksever Celik
Despite its high prevalence, diagnosis is frequently delayed for 6–11 years because symptoms overlap with multiple gastrointestinal, urologic, and gynecologic disorders. Laparoscopy with histopathological confirmation remains the diagnostic gold standard, often preceded by imaging studies such as ultrasound or MRI…
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