Genetic Overlap Between Endometriosis and Autoimmune Disorders
Women with endometriosis may face a higher risk of developing several immune-related conditions, according to a large study led by Rahmioglu and Zondervan, published in Human Reproduction. Using data from more than 270,000 women in the UK Biobank, the researchers…
Key Points Lay SummaryLeiomyomas have similar genetic background with endometriosis
This multicenter research conducted in institutions located in the USA and UK published in Nature Communications, October 2019 issue. Leiomyomata of the uterus are hormone-dependent tumors with an estimated prevalence of about 20-77%. İn several publications. Research in uterine leiomyoma…
Key Points Lay SummaryThe genetic predisposition to endometriosis
Endometriosis is an estrogen-dependent gynecological disease mostly encountered in reproductive-aged women. Although endometrium is a non-malignant disease, its symptoms can range from mild to severe due to the inflammation that ectopic endometrial tissue forms around itself. The exact etiopathogenetic mechanism…
Key Points Lay SummaryNew Link Between Endometriosis and Genetics?
Two new genes have been identified that may be associated with endometriosis. This finding increases our understanding of the biology of endometriosis and may take us one small step further towards the development of new ways of treating the condition. …
Key Points Lay SummaryUpdates in the Field of Endometriosis: Genetics
This chapter written by Krishnamoorthy and Decherney re-evaluate the literature concerning the genetics of endometriosis. The genetic mechanisms and signaling pathways that led to endometriosis are updated and the tools that help researchers find these abnormal genes and pathways are…
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