Is it iron that calls vessels to form endometriosis

Is it iron that calls vessels to form endometriosis By Bahar Yuksel

The trigger mechanism of endometriosis formation is still under investigation. But it is clear that there is an iron overload on endometriotic lesions. In the study conducted by Guojing Li et al, the mechanism of iron on endometriosis formation has been…

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Erastin, Ferroptosis and Endometriosis

Erastin, Ferroptosis and Endometriosis By Dr. Youngran Park

Iron overload has been linked to endometriosis. There are abundant free iron and high oxidation in ectopic lesions, probably due to retrograde menstruation. Interestingly, iron overload in endometriosis activates NF-kB signaling and results in proinflammatory communication. More clear pieces of…

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Defective “ferroptosis”: a new pathogenetic explanation of endometriosis

Defective “ferroptosis”: a new pathogenetic explanation of endometriosis By Nasuhi Engin Aydin

Dr. Ng and associates from Tufts University School of Medicine, Boston, USA made a comprehensive review of the role of the iron element in the development of endometriotic lesions. Though iron element is essential for cell survival, and its deficiency is important…

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