The link between autoimmunity and endometriosis

The link between autoimmunity and endometriosis By Yu Yu

A popular model to explain the etiology of endometriosis is Sampson’s theory of retrograde menstruation. In this model, the viable endometrial tissue is spread and attached to the peritoneal cavity through the fallopian tubes during menstruation, resulting in an inflammatory…

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Polymorphisms of STAT4 gene in the pathogenesis of endometriosis

Polymorphisms of STAT4 gene in the pathogenesis of endometriosis By Dr. Youngran Park

Endometriosis is one of the most common gynecological diseases in reproductive-age women characterized by the occurrence of endometrial tissue outside the uterine cavity. Researchers have put forward numerous hypotheses to explain ectopic endometrial tissue, and the bulk of the evidence…

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Endometriosis in adolescents

Endometriosis in adolescents By Irem Onur

Dr. Mama S. T. from Cooper University Hospital, Camden, New Jersey, USA, recently has published his review on advances in the management of endometriosis in the adolescent in the journal “Current Opinion Obstetrics and Gynecology”. In adolescence, there is a…

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A review on the role of immune cells on the pathogenesis of endometriosis

A review on the role of immune cells on the pathogenesis of endometriosis By Murat Osman

Immune cells play a vital role in the homeostasis against infectious pathogens but also in the pathogenesis of endometriosis. Recent research has suggested that different immune cells have unique roles in this pathogenesis. Neutrophils, which are typically the primary acute…

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Analysis of suppressive regulatory T cells and latent transforming growth factor-β-expressing macrophages in endometriosis peritoneal fluid

Analysis of suppressive regulatory T cells and latent transforming growth factor-β-expressing macrophages in endometriosis peritoneal fluid By Yu Yu

One prominent theory of endometriosis origin is the implantation of steroid hormone-sensitive endometrial cells and tissues on the peritoneal surface during retrograde menstruation and caused an inflammatory response. While women exhibit retrograde menstruation, endometriosis may be affected by women suffering…

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