IL-37 regulates ectopic endometrial stromal cells to prevent endometriosis

IL-37 regulates ectopic endometrial stromal cells to prevent endometriosis By Dr. Youngran Park

Endometriosis has been identified as a chronic inflammatory disease. It has been shown that in the plasma and peritoneal fluid, women with endometriosis exhibit aberrant numbers of immune cells and concentrations of cytokines and chemokines that promote a chronic inflammatory…

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S100A6 May be a Promising Target for Endometriosis Treatments

S100A6 May be a Promising Target for Endometriosis Treatments By Kasthuri Nair

Peng et al., a group primarily from the Zhejiang University Medical College, recently published a paper in Gynecological Endocrinology titled “Upregulation of S100A6 in patients with endometriosis and its role in ectopic endometrial stromal cells.” This paper delineates a study…

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Autophagy in endometriosis

Autophagy in endometriosis By Dr. Youngran Park

Endometriosis is a common gynecologic disease affecting both fertile (5-10%) and infertile (20-50%) women, and it commonly causes chronic pelvic pain, dysmenorrhea, and infertility. Recent research found that the autophagy exerts a pro-apoptotic effect on normal human endometrial cells and…

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The Role of IL-35 in the Pathogenesis of Endometriosis

The Role of IL-35 in the Pathogenesis of Endometriosis By Kasthuri Nair

The molecular mechanism that drives endometriosis remains elusive to this day. Zhang et al believe that interleukin 35 (IL-35) plays a role in the pathogenesis of the disease. Their recent publication in Reproductive Sciences titled “Upregulation of Interleukin 35 in…

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