Autophagy, Endometrium and Endometriosis

Autophagy, Endometrium and Endometriosis By Dr. Youngran Park

Autophagy, or autophagocytosis, is a self-digestion process by which cells recycle non-functional proteins to repurpose them. Unwanted cellular parts in cytosolic material are first isolated within double-membrane vesicles called the autophagosome, which subsequently fuses with the acidic lysosome. Autophagy is a survival…

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Ovarian, breast and endometrial cancer coexisting with endometriosis.

Ovarian, breast and endometrial cancer coexisting with endometriosis. By Selma Oransay

The invasive nature of endometriosis results in calling the disease " benign cancer". The transformation of endometriosis to malignancy is rare, but when compared to the general population, the relative risk of developing ovarian cancer is 4.2 times greater especially…

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Drugs targeting estrogen biosynthesis opening up new approaches to the treatment of endometriosis.

Drugs targeting estrogen biosynthesis opening up new approaches to the treatment of endometriosis. By Selma Oransay

Gibson et al., from the Univerity of Edinburgh, UK, take over a new interest about endometriosis occurrence and progress by endometrial tissue intracrinology in their recently online published article in International Journal of Molecular Sciences. The authors summarize the last…

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Vitamin D and Endometriosis

Vitamin D and Endometriosis By Nasuhi Engin Aydin

Scientists from Milan, Italy reviewed the effects of vitamin D on the reproductive health, and in particular "endometriosis" in their article which appeared in International Journal of Molecular Sciences. Vitamin D (VD), is a steroid hormone that is activated in…

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An update of estrogen receptors on human disease

An update of estrogen receptors on human disease By Yu Yu

Estrogens and its receptors influence numerous human physiological processes. Two estrogen receptors exist, including estrogen receptor α (ERα) and ERβ. Hence, it is essential to elucidate the functions of these receptors in healthy and diseased states. This is particularly important…

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Laparoscopic Hysterectomy as Effective as Total Abdominal Hysterectomy, Study Suggests

Laparoscopic Hysterectomy as Effective as Total Abdominal Hysterectomy, Study Suggests By Ezio Rosato

Laparoscopic hysterectomy, a minimally invasive surgical procedure that is used to remove the uterus, results in similar rates of disease-free survival among women with stage 1 endometrial cancer as the standard abdominal hysterectomy, showed a study published in The Journal…

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