Inhibition of PI3K/AKT/mTOR pathway for the treatment of endometriosis.

Inhibition of PI3K/AKT/mTOR pathway for the treatment of endometriosis. By Dr. Youngran Park

Dr. Matsuzaki et al. (2018) published a paper entitled ‘In vitro and in vivo effects of MK2206 and chloroquine combination therapy on endometriosis’ showing that the efficacy of MK2206, an Akt inhibitor, in combination with chloroquine for inducing autophagy in…

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Autophagy in endometriosis: Friend or foe?  

Autophagy in endometriosis: Friend or foe?   By Dr. Youngran Park

Endometriosis is a chronic, estrogen-dependent disease and affects an estimated 10% of the female population of reproductive age. Unfortunately, the etiology of endometriosis is not clear. Recently emerging evidence shows that there is a close relationship between endometriosis and autophagy.…

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