Macrophages Become Myofibroblasts in Endometriosis Fibrosis

Macrophages Become Myofibroblasts in Endometriosis Fibrosis By Ayse Ayhan

Fibrosis is a major but often underrecognized feature of endometriosis. It contributes to pain, adhesions, impaired endometrial receptivity, and progressive lesion stiffness. Although fibrosis is well documented in both ectopic lesions and the eutopic endometrium, the exact cellular mechanisms driving…

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A Balancing Act: How Endometriosis Invades the Body

A Balancing Act: How Endometriosis Invades the Body By Murat Osman

Endometriosis is a disease defined by the presence of endometrial tissue outside of the uterine cavity. Ectopic endometrial tissues have been shown to have some features that mimic malignancy. For example, endometriosis can invade surrounding structures and attach to surfaces such…

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