Endometriosis and nuclear receptors

Endometriosis and nuclear receptors By Dr. Youngran Park

It is well recognized that endometriosis is a steroid-dependent disorder. In endometrial stromal cells, progesterone regulates retinoic acid production and action. Retinoids also act via a number of nuclear receptors (NRs) and are involved in normal endometrial function and endometriosis. Estrogen…

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A highly sensitive Immunohistochemical Marker for Stromal Cells in endometriosis

A highly sensitive Immunohistochemical Marker for Stromal Cells in endometriosis By Engin Aydin

Endometriosis is diagnosed histopathologically by the presence of endometrium-like tissues outside the uterus. Positive CD10 immunohistochemistry, highlighting stromal cells of the endometrium, is a useful adjunct for pathologists in the tissue diagnosis. However, CD10 expression is not specific to endometrial stromal…

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