Anti-IL-8 antibody ameliorates inflammation and fibrosis: A promising treatment for endometriosis
Endometriosis is a condition associated with chronic inflammation and fibrosis, and there are limitations and side effects with current treatments such as hormonal therapy and surgery. Interleukin-8 (IL-8) and monocyte chemoattractant protein-1 (MCP1) are inflammatory cytokines that play a crucial…
Key Points Lay SummaryEnhanced local and systemic inflammatory cytokine mRNA expression in women with endometriosis
Endometriosis is not only characterized by the implantation of endometriotic tissue outside of the uterine cavity but also necessitates an impaired immune response. It is suggested that abnormal immunological mechanisms causing the dysfunction of immune cells and their mediators are…
Key Points Lay SummaryA Balancing Act: How Endometriosis Invades the Body
Endometriosis is a disease defined by the presence of endometrial tissue outside of the uterine cavity. Ectopic endometrial tissues have been shown to have some features that mimic malignancy. For example, endometriosis can invade surrounding structures and attach to surfaces such…
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