By Özge ÖzkayaMPO not a Good Biomarker for Endometriosis, Research Suggests
By Özge Özkaya
A biomarker is a molecule naturally occurring in the body, which can be an indicator of health or disease.
Lay Summary
By Ezio RosatoNew Molecular Targets for the Treatment of Endometriosis-Associated Pain
By Ezio Rosato
The study identifies potential new targets for alleviating chronic pelvic pain that afflicts many women with endometriosis.
Lay Summary
Women with Endometriosis May Require Additional Care During Pregnancy and Labour
By Özge Özkaya
The researchers compared the pregnancy outcome of these women with the pregnancy outcome of 300 women who were not diagnosed with endometriosis.
Lay Summary
By Yu YuImmune substances in peritoneal fluid for endometriosis diagnosis and armamentarium
By Yu Yu
There is a pattern of cytokine alterations that can be used to understand endometriosis pathogenesis and device diagnostic or therapeutic tools.
Key Points Lay Summary
Characteristics of Ovarian Endometriotic Cysts Could Help Determine Whether Endometrioma Will Reoccur
By Özge Özkaya
They found that there were statistically significant differences between patients in whom endometrioma reoccurred and those for whom it did not in terms of age, thickness of fibrosis, and depth of penetration of endometrial tissue into the cyst wall.
Lay Summary
Metabolomic profiling and biochemical evaluation of the follicular fluid of endometriosis patients.
By Yu Yu
Metabolism products of our body, called metabolites; can be used to derive useful information to identify disease-related markers such as endometriosis, study suggest.
Key Points Lay Summary
Genetic Variations May Link Risk of Endometriosis and Ovarian Cancer
By Özge Özkaya
Identifying genetic risk factors that are common to the two diseases might help scientists better understand the molecular events associated with the development of both diseases, and potentially develop treatments that could treat both diseases.
Lay Summary
Increased Oxidative Stress in Endometriosis may Be Linked to Higher Risk of Ovarian Cancer
By Ezio Rosato
Increased oxidative stress might contribute to higher risk of ovarian cancer in women with endometriosis, a new study found.
Lay Summary
By Murat OsmanComplexity of Urinary Tract Endometriosis: Highlights from a Review
By Murat Osman
This review paper by Nezhat et al. offers a descriptive yet succinct overview of the recent understanding of the pathogenesis, presentation, diagnosis, and clinical management of urinary tract endometriosis.
Key Points Lay Summary
By Karime Kalil MachadoEndometriosis doubles the risk of sexual dysfunction
By Karime Kalil Machado
A statistically significant difference was present in all domains evaluated, including sexual desire, sexual arousal, pain during intercourse, orgasm and/or sexual satisfaction and overall sexual dysfunction.
Lay Summary
By Asli Bahadirli TalbottDiet & Endometriosis
By Asli Bahadirli Talbott
In a recently published review paper in Ginekologia Polska, Jurkiewicz-Przondziono et al. have summarized their literature findings. Scientific evidence shows that diet and lifestyle may influence inflammation in the body, estrogen activity, menstrual cycle and prostaglandin metabolism. The team listed…
Key Points Lay Summary
Laparoscopic Hysterectomy as Effective as Total Abdominal Hysterectomy, Study Suggests
By Ezio Rosato
“A laparoscopic hysterectomy is an appropriate approach for the treatment of stage 1 endometrial cancer,” the authors concluded.
Lay Summary
Elagolix (ABT-620) for endometriosis pain?
By Yu Yu
Elagolix is an active brain hormone antagonist (called gonadotropin-releasing hormone which is acting on ovaries) has just completed clinical trial for endometriosis-associated pain. The review article by Alessandro et al in Archives of Gynecology and Obstetrics summarized the current research…
Key Points Lay Summary
Endometriosis Symptoms Often Go Unrecognized, Nationwide Survey Finds
By Özge Özkaya
The findings indicated that almost half (42%) of the women surveyed did not know that painful intercourse could be a sign of endometriosis. Importantly, 20% of healthcare professionals rarely or never asked their patients about painful intercourse.
Lay Summary
Desogestrel Could Effectively Be Used to Reduce Endometriosis-Related Pain Following Surgery
By Özge Özkaya
In order to test whether desogestrel is able to relieve endometriosis-related pain, researchers conducted a double-blind and randomized placebo-controlled trial (where neither the patients nor the clinician know who is getting the drug and who is getting a placebo), in…
Lay Summary
$363,000 to Identify Markers of Pain in Endometriosis Awarded to St Louis Scientists
By Özge Özkaya
"Our goal is to take this exciting basic science work a step further and study to see if these molecules can serve as biomarkers in people, helping us to identify patients who would and who would not benefit from drugs…
Lay Summary
Women with Endometriosis Should be Closely Monitored During Pregnancy and Birth, Study Suggests
By Özge Özkaya
Almost all pregnancy complications occurred more frequently in women with endometriosis than in women without endometriosis. These included the risk of preeclampsia, bleeding, placental abruption, placental previa (where the placenta lies low in the uterus and partially or completely covers…
Lay Summary
New Method Could Help Diagnose Endometriosis in a Non-invasive Manner
By Özge Özkaya
The authors concluded that the study of proteins based on high-resolution mass spectrometry could be a non-invasive way of diagnosing endometriosis. They also noted that their results confirm endometriosis as a chronic inflammatory disease.
Lay Summary
Women With a Higher BMI May Have a Lower Risk of Endometriosis
By Özge Özkaya
Based on the results of these studies, the researchers calculated that the risk of endometriosis fell by 33% with each 5 kg/m2 increase in BMI. Moreover, obese women (defined as having a BMI between 30 and 40) had 11% less…
Lay Summary
Endometriosis Can Reduce Sleep Quality and Negatively Impact Patient’s Quality of Life Study Suggests
By Özge Özkaya
The researchers assessed sleep quality, daytime sleepiness, and insomnia in all women using the Pittsburgh Sleep Quality Index, the Epworth sleepiness scale, and the Insomnia Severity Index respectively, all self-evaluating questionnaires.
Lay Summary