MPO not a Good Biomarker for Endometriosis, Research Suggests

MPO not a Good Biomarker for Endometriosis, Research Suggests  - Özge  Özkaya By Özge Özkaya

A biomarker is a molecule naturally occurring in the body, which can be an indicator of health or disease.


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New Molecular Targets for the Treatment of Endometriosis-Associated Pain

New Molecular Targets for the Treatment of Endometriosis-Associated Pain - Ezio  Rosato By Ezio Rosato

The study identifies potential new targets for alleviating chronic pelvic pain that afflicts many women with endometriosis.


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Women with Endometriosis May Require Additional Care During Pregnancy and Labour

Women with Endometriosis May Require Additional Care During Pregnancy and Labour - Özge  Özkaya By Özge Özkaya

The researchers compared the pregnancy outcome of these women with the pregnancy outcome of 300 women who were not diagnosed with endometriosis.


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Immune substances in peritoneal fluid for endometriosis diagnosis and armamentarium

Immune substances in peritoneal fluid for endometriosis diagnosis and armamentarium - Yu  Yu By Yu Yu

There is a pattern of cytokine alterations that can be used to understand endometriosis pathogenesis and device diagnostic or therapeutic tools.


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Characteristics of Ovarian Endometriotic Cysts Could Help Determine Whether Endometrioma Will Reoccur

Characteristics of Ovarian Endometriotic Cysts Could Help Determine Whether Endometrioma Will Reoccur - Özge  Özkaya By Özge Özkaya

They found that there were statistically significant differences between patients in whom endometrioma reoccurred and those for whom it did not in terms of age, thickness of fibrosis, and depth of penetration of endometrial tissue into the cyst wall.


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Metabolomic profiling and biochemical evaluation of the follicular fluid of endometriosis patients.

Metabolomic profiling and biochemical evaluation of the follicular fluid of endometriosis patients. - Yu  Yu By Yu Yu

Metabolism products of our body, called metabolites; can be used to derive useful information to identify disease-related markers such as endometriosis, study suggest.


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Genetic Variations May Link Risk of Endometriosis and Ovarian Cancer

Genetic Variations May Link Risk of Endometriosis and Ovarian Cancer  - Özge  Özkaya By Özge Özkaya

Identifying genetic risk factors that are common to the two diseases might help scientists better understand the molecular events associated with the development of both diseases, and potentially develop treatments that could treat both diseases.


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Increased Oxidative Stress in Endometriosis may Be Linked to Higher Risk of Ovarian Cancer

Increased Oxidative Stress in Endometriosis may Be Linked to Higher Risk of Ovarian Cancer  - Ezio  Rosato By Ezio Rosato

Increased oxidative stress might contribute to higher risk of ovarian cancer in women with endometriosis, a new study found.


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Complexity of Urinary Tract Endometriosis: Highlights from a Review

Complexity of Urinary Tract Endometriosis: Highlights from a Review - Murat  Osman By Murat Osman

This review paper by Nezhat et al. offers a descriptive yet succinct overview of the recent understanding of the pathogenesis, presentation, diagnosis, and clinical management of urinary tract endometriosis.


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Endometriosis doubles the risk of sexual dysfunction

Endometriosis doubles the risk of sexual dysfunction  - Karime Kalil   Machado By Karime Kalil Machado

A statistically significant difference was present in all domains evaluated, including sexual desire, sexual arousal, pain during intercourse, orgasm and/or sexual satisfaction and overall sexual dysfunction.


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Diet & Endometriosis

Diet & Endometriosis - Asli Bahadirli  Talbott By Asli Bahadirli Talbott

In a recently published review paper in Ginekologia Polska, Jurkiewicz-Przondziono et al. have summarized their literature findings. Scientific evidence shows that diet and lifestyle may influence inflammation in the body, estrogen activity, menstrual cycle and prostaglandin metabolism. The team listed…


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Laparoscopic Hysterectomy as Effective as Total Abdominal Hysterectomy, Study Suggests

Laparoscopic Hysterectomy as Effective as Total Abdominal Hysterectomy, Study Suggests - Ezio  Rosato By Ezio Rosato

“A laparoscopic hysterectomy is an appropriate approach for the treatment of stage 1 endometrial cancer,” the authors concluded.


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Elagolix (ABT-620) for endometriosis pain?

Elagolix (ABT-620) for endometriosis pain? - Yu  Yu By Yu Yu

Elagolix is an active brain hormone antagonist (called gonadotropin-releasing hormone which is acting on ovaries) has just completed clinical trial for endometriosis-associated pain. The review article by Alessandro et al in Archives of Gynecology and Obstetrics summarized the current research…


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Endometriosis Symptoms Often Go Unrecognized, Nationwide Survey Finds

Endometriosis Symptoms Often Go Unrecognized, Nationwide Survey Finds - Özge  Özkaya By Özge Özkaya

The findings indicated that almost half (42%) of the women surveyed did not know that painful intercourse could be a sign of endometriosis. Importantly, 20% of healthcare professionals rarely or never asked their patients about painful intercourse.


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Desogestrel Could Effectively Be Used to Reduce Endometriosis-Related Pain Following Surgery

Desogestrel Could Effectively Be Used to Reduce Endometriosis-Related Pain Following Surgery - Özge  Özkaya By Özge Özkaya

In order to test whether desogestrel is able to relieve endometriosis-related pain, researchers conducted a double-blind and randomized placebo-controlled trial (where neither the patients nor the clinician know who is getting the drug and who is getting a placebo), in…


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$363,000 to Identify Markers of Pain in Endometriosis Awarded to St Louis Scientists

$363,000 to Identify Markers of Pain in Endometriosis Awarded to St Louis Scientists - Özge  Özkaya By Özge Özkaya

"Our goal is to take this exciting basic science work a step further and study to see if these molecules can serve as biomarkers in people, helping us to identify patients who would and who would not benefit from drugs…


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Women with Endometriosis Should be Closely Monitored During Pregnancy and Birth, Study Suggests

Women with Endometriosis Should be Closely Monitored During Pregnancy and Birth, Study Suggests - Özge  Özkaya By Özge Özkaya

Almost all pregnancy complications occurred more frequently in women with endometriosis than in women without endometriosis. These included the risk of preeclampsia, bleeding, placental abruption, placental previa (where the placenta lies low in the uterus and partially or completely covers…


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New Method Could Help Diagnose Endometriosis in a Non-invasive Manner

New Method Could Help Diagnose Endometriosis in a Non-invasive Manner - Özge  Özkaya By Özge Özkaya

The authors concluded that the study of proteins based on high-resolution mass spectrometry could be a non-invasive way of diagnosing endometriosis. They also noted that their results confirm endometriosis as a chronic inflammatory disease.


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Women With a Higher BMI May Have a Lower Risk of Endometriosis

Women With a Higher BMI May Have a Lower Risk of Endometriosis - Özge  Özkaya By Özge Özkaya

Based on the results of these studies, the researchers calculated that the risk of endometriosis fell by 33% with each 5 kg/m2 increase in BMI. Moreover, obese women (defined as having a BMI between 30 and 40) had 11% less…


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Endometriosis Can Reduce Sleep Quality and Negatively Impact Patient’s Quality of Life Study Suggests

Endometriosis Can Reduce Sleep Quality and Negatively Impact Patient’s Quality of Life  Study Suggests - Özge  Özkaya By Özge Özkaya

The researchers assessed sleep quality, daytime sleepiness, and insomnia in all women using the Pittsburgh Sleep Quality Index, the Epworth sleepiness scale, and the Insomnia Severity Index respectively, all self-evaluating questionnaires.


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