Ancient Genetic Variants and Modern Pollutants in Endometriosis Risk

Ancient Genetic Variants and Modern Pollutants in Endometriosis Risk By Selma Oransay

Researchers are increasingly examining how genetic susceptibility interacts with modern environmental pollutants to influence the development of endometriosis. In a new study published in the European Journal of Human Genetics, a team led by Dr.A.Mantzouratou investigated whether inherited regulatory variants may…

Key Points Lay Summary

Kisspeptin and its Receptor in the Pathogenesis of Endometriosis

Kisspeptin and its Receptor in the Pathogenesis of Endometriosis By Irem Onur

It is known that matrix metalloproteinases (MMP) may play a role in the pathogenesis of endometriosis. For example, the upregulation of MMP-2 and MMP-9 may enhance the degradation of extracellular matrix proteins, facilitating cell migration and invasion. Kisspeptin (KISS1, also…

Key Points Lay Summary