A nonhormonal treatment of endometriosis: Dichloroacetate

A nonhormonal treatment of endometriosis: Dichloroacetate By Irem Onur

In women with endometriosis, peritoneal mesothelial cells show higher glycolysis, lower mitochondrial respiration, decreased enzymatic activity of pyruvate dehydrogenase and increased production of lactate compared to women without the disease. Transforming growth factorβ1 and lactate are elevated in the peritoneal…

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