Quantification of nerve bundle density as a biomarker for endometriosis utilizing PGP9.5 immunostaining
Scientists from Netherlands and Canada have published their authentic study on immunohistochemically assessed nerve fiber bundles of endometriotic tissues in a recent issue of Frontiers in Reproductive Health. Endometriotic tissues have nerve fibers which are stimulated in inflammatory processes leading…
Key Points Lay SummaryIs the presence of nerve fibers in the endometrium associated with endometriosis?
Endometriosis is a common disease in reproductive women and diagnostic imaging have a limited role in its diagnosis. The gold standard diagnostic method remains to be the histopathological examination of the tissue obtained via laparoscopy. One of its most common…
Key Points Lay SummaryNew Signaling Pathway Could Be Crucial in the Development of Endometriosis
RAMP1 signaling is crucial for growth and blood and lymphatic vessel formation in endometrial tissue, according to a new study published in the Journal of Cellular and Molecular Medicine. This suggests that blocking RAMP1 could be a new way to…
Key Points Lay Summary