Inhibition of Histone methyltransferase for fighting endometriosis

Inhibition of Histone methyltransferase for fighting endometriosis By Dr. Youngran Park

Although the histone methyltransferase EZH2 and its product H3K27me3 are well studied in cancer, little is known about their role and potential as therapeutic targets in endometriosis. It has been previously reported that the endometriotic lesions are characterized by global…

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Epigenetic regulation of the pathological process in endometriosis.

Epigenetic regulation of the pathological process in endometriosis. By Dr. Youngran Park

Epigenetic mechanisms have been recognized as important players in the development of a broad range of human diseases including endometriosis. A growing body of evidence shows that the remodeling of retrograde endometrial tissues to the ectopic endometriotic lesions involves multiple epigenetic…

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