Could a defect in phagocytosis cause endometriosis?

Could a defect in phagocytosis cause endometriosis? By Yu Yu

The macrophages are important immune cells in the peritoneal cavity because they function to remove aberrant cells or tissues by the process of phagocytosis. In endometriosis, there is an increased number of peritoneal macrophages and heightened production of inflammation molecules…

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Antibiotic therapy for endometriosis

Antibiotic therapy for endometriosis By Yu Yu

Current treatments for endometriosis are surgery and hormone therapy; however, these approaches may have significant side effects and do not prevent a recurrence. Therefore, alternative treatment modalities for endometriosis is needed. Recently, the idea that endometriosis may be influenced by…

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Study Sheds Light on the Molecular Mechanism of Endometriosis Development

Study Sheds Light on the Molecular Mechanism of Endometriosis Development By Özge Özkaya

A protein called transforming growth factor-beta1 (TGF-B1) enhances the capacity of endometriotic cells or cells that make up the lining of the uterus to migrate, invade, and colonize other areas in the body. This is according to a study published…

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Another Study Suggesting That Endometriosis May Be a Disease Associated With Immune System Dysfunction

Another Study Suggesting That Endometriosis May Be a Disease Associated With Immune System Dysfunction By Özge Özkaya

An immune system protein called TGF-β in the peritoneal fluid or fluid that lubricates the lining of the abdominal wall and pelvic cavity may be creating an environment favorable for the formation of endometrial lesions. This is according to a…

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New Target for Endometriosis Treatment?

New Target for Endometriosis Treatment? By Özge Özkaya

NR4A1 could be a novel target for the treatment of endometriosis, according to a study published in the scientific journal Cell Physiology and Biochemistry. NR4A1 is a receptor protein involved in cell division, inflammation, and programmed cell death. The development…

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Research Sheds Light Onto Molecular Mechanism of Endometriosis

Research Sheds Light Onto Molecular Mechanism of Endometriosis By Özge Özkaya

A cell signaling molecule called transforming growth factor β 1 or TGF-β1 is involved in the development of endometriosis, a new study found. A better understanding of the molecular events associated with the development of this disease could help scientists…

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TGF-β1 Increases Cell Adhesion and Drives Disease Progression

TGF-β1 Increases Cell Adhesion and Drives Disease Progression By Kasthuri Nair

Without a doubt, the mechanism that drives endometriosis disease progression is complicated. Choi et al. look to elucidate one part of this complex process. They seek to understand the role of transforming growth factor β1 (TGF-β1) in the initial adhesion…

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