The association between inflammatory cytokines and fertility in women with endometriosis

The association between inflammatory cytokines and fertility in women with endometriosis By Hale Goksever Celik

Women with endometriosis suffer not only from a broad spectrum of symptoms including pain including dysmenorrhea, dyspareunia, and chronic pelvic pain but also fertility problems. Endometriosis-associated infertility develops depending on a combination of several mechanisms such as distorted pelvic anatomy,…

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What happens to women with endometriosis after menopause?

What happens to women with endometriosis after menopause? By Selma Oransay

Endometriosis affects women in their reproductive period of life, with expected regression of lesions in the postmenopausal period. Literature about postmenopausal endometriosis assessing the prevalence, pathogenesis, and treatment is limited. As 2-5 % of postmenopausal women are affected by this uncommon condition, developing stress…

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Seven Hormonal Biomarkers for Diagnosing Endometriosis

Seven Hormonal Biomarkers for Diagnosing Endometriosis By Dr. Youngran Park

Endometriosis is an inflammatory condition characterized by implantation and invasive growth of endometrial tissue outside the uterine cavity. Although it is benign, endometriosis has cancer-like features, a mutation profile similar to that of ovarian cancer, and increased ovarian cancer risk.…

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Novel inhibitors of estrogen biosynthesis

Novel inhibitors of estrogen biosynthesis By Dr. Youngran Park

Endometriosis is a chronic benign disease which is estrogen-dependent. Estradiol creates a positive feedback loop with the synthesis of pro-inflammatory mediators, which sustains further disease establishment and causes the pain symptoms. However, hormone therapies do not cure definitively endometriosis, because…

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New Link Between Endometriosis and Genetics?

New Link Between Endometriosis and Genetics? By Özge Özkaya

Two new genes have been identified that may be associated with endometriosis. This finding increases our understanding of the biology of endometriosis and may take us one small step further towards the development of new ways of treating the condition. …

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Coumarin based compounds found to inhibit the estradiol synthesis pathway

Coumarin based compounds found to inhibit the estradiol synthesis pathway By Murat Osman

Endometriosis is a disease characterized by ectopic endometrial tissue outside the endometrium. Several biochemical and molecular pathways have been researched and used to alleviate endometriosis symptoms by inhibiting key molecules involved in the menstrual cycle. This review paper by Niinivehmas…

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EFA Medical Conference 2017: "Ovarian Cancer" Presentation by  Dr. Jeannine Villella

EFA Medical Conference 2017: By Kasthuri Nair

Dr. Jeannine Villella, the Chair of Gynecologic Oncology in the Department of OBGYN at Lenox Hill, presented at the 2017 EFA Medical Conference. Her presentation was titled “Ovarian Cancer, ” and she discussed the similarities, differences, and links between ovarian…

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A Potential New Drug for Endometriosis?

A Potential New Drug for Endometriosis?  By Özge Özkaya

A steroid derivative called PBRM could be a new emerging drug to treat endometriosis according to a study by Canadian scientists. In the study that was published in The Journal of Steroid Biochemistry and Molecular Biology, researchers characterized the pharmaceutical…

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EFA Medical Conference 2017: "Fertility Preservation to BRCA Mutations" Presentation by Dr. Kutluk Oktay

EFA Medical Conference 2017: By Kasthuri Nair

Dr. Kutluk Oktay is the Director of the Laboratory of Molecular Reproduction & Fertility Preservation as well as a Professor of OBGYN at Yale University School of Medicine. Dr. Oktay also presented at the EFA 2017 Medical Conference, and his…

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EFA Medical Conference 2017: "Hormone and Cytokine Sensitivity in Endometriosis" Presentation by Dr. Robert Taylor

EFA Medical Conference 2017: By Kasthuri Nair

The first presenter of the “Estrogen from Inflammation to Cancer: A Distant Link?” section of EFA 2017 Medical Conference was Dr. Robert Taylor from Wake Forest University Health Sciences. Dr. Taylor’s presentation was titled “Hormone and Cytokine Sensitivity in Endometriosis.”…

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EFA Medical Conference 2017: “Literature Review, Our Data, and Case Presentations” by Dr. Karli Goldstein

EFA Medical Conference 2017: “Literature Review, Our Data, and Case Presentations” by Dr. Karli Goldstein By Özge Özkaya

Dr. Karli Goldstein started her presentation with a brief literature review on the relationship between endometriosis and breast cancer. She focused on a research article by Dr. Spandidos and colleagues, which was the first epidemiological study that examined the possible…

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EFA Medical Conference 2017: "NIH Funding - Present and Future" Presentation by Dr. Lisa Halvorson

EFA Medical Conference 2017: By Kasthuri Nair

Dr. Lisa Halvorson, the Chief at the Gynecologic Health and Disease Branch at the National Institute of Health (NIH)/NICHD/HHS, gave a presentation titled “NIH Funding - Present and Future” at the EFA 2107 Medical conference. Dr. Halvorson’s presentation began with…

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EFA Medical Conference 2017: "Breast Cancer in Young Women; Early Diagnosis Timely Intervention" Presentation by Dr. Stephanie Bernik

EFA Medical Conference 2017: By Kasthuri Nair

Dr. Stephanie Bernik is the Chief of Surgical Oncology of Surgery and General Surgery at the Lenox Hill Hospital. She recently presented at the EFA 2017 Medical Conference, and her presentation was titled “Breast Cancer in Young Women; Early Diagnosis…

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EFA Medical Conference 2017: "Prophylactic Mastectomy and Breast Reconstruction" Presentation by Dr. Oren Lerman

EFA Medical Conference 2017: By Özge Özkaya

Dr. Oren Lerman, a plastic and reconstructive surgeon at Lenox Hill Hospital in New York City, described the reconstructive options of a woman who has been or is going to go through a mastectomy (removal of breast tissues) whether it…

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EFA Medical Conference 2017: "Endometriosis: hormonal or surgical? My reality!" Presentation by Dr. Harry Reich

EFA Medical Conference 2017: By Kasthuri Nair

Dr. Harry Reich, the Former Director of Advanced Laparoscopic Surgery at Columbia University Department of OBGYN, was the last speaker in the Mission and History part of the EFA 2017 Medical Conference. His presentation was titled “Endometriosis: hormonal or surgical?…

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EFA Medical Conference 2017: "Cells Are the New Cure" Presentation by Dr. Max Gomez

EFA Medical Conference 2017: By Kasthuri Nair

Dr. Max Gomez is an award-winning broadcast journalist, CBS News Medical Correspondent, and a presenter at the EFA 2017 Medical Conference. Dr. Gomez’s presentation was titled “Cells Are the New Cure: The Cutting-Edge Medical Breakthroughs That Are Transforming Our Health.”…

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What is the role of hormones on the function and development of the brain?

What is the role of hormones on the function and development of the brain? By Murat Osman

Dr. Sarah L. Berga, Professor, and Chair of Obstetrics and Gynecology Wake Forest School of Medicine aim to talk about the effects of sex hormones such as estrogens and progestins on brain health with an emphasis on the neuroprotective characteristics…

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EFA.MC.2017.“The Abnormal Embryos That Aren’t”,“Tens of thousands of women thought they couldn't have babies: But what if they could.”Dr. Norbert Gleicher Dr. Monica Halem

EFA.MC.2017.“The Abnormal Embryos That Aren’t”,“Tens of thousands of women thought they couldn't have babies: But what if they could.”Dr. Norbert Gleicher Dr. Monica Halem By Özge Özkaya

The presentation started with the story of Monica Halem who had endometriosis and had been trying to conceive using in vitro fertilization VF), but was told that none of her fertilized embryos would be viable based on pre-implantation genetic screening…

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EFA Medical Conference 2017: EFA Research Grants Presentation by Dr. Serin Seckin

EFA Medical Conference 2017: EFA Research Grants Presentation by Dr. Serin Seckin By Kasthuri Nair

Dr. Serin Seckin, a Resident Physician at Mount Sinai Health System, gave a presentation during the 2017 Medical Conference titled “EFA Research Grants.” This presentation delineated and went into some detail about the research grants worth over $400,000 that were…

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EFA Medical Conference 2017: "The Environmental Risks of Breast Cancer" Presentation by Dr. Marisa Weiss

EFA Medical Conference 2017: By Kasthuri Nair

The second speaker in the subsection of the conference titled “Estrogen from Inflammation to Cancer: A Distant Link?” was Dr. Marisa Weiss and she gave a presentation titled “The Environmental Risks of Breast Cancer: Common Ground with Endometriosis.” Dr. Weiss…

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EFA Medical Conference 2017: Welcome Presentation by Dr. Tamer Seckin

EFA Medical Conference 2017: Welcome Presentation by Dr. Tamer Seckin By Kasthuri Nair

The first part of the Endometriosis Foundation of America’s 2017 Medical Conference delved into the mission and history of the Endometriosis Foundation of America. The first presenter was Dr. Tamer Seckin, a renowned surgeon, and gynecologist who is also the…

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Retinoic Acid Signaling Involved in Endometrial Decidualization

Retinoic Acid Signaling Involved in Endometrial Decidualization By Murat Osman

Decidualization occurs in the eutopic endometrium during the luteal phase and is controlled by signaling pathways such as cyclic adenosine monophosphate (cAMP) and progesterone. Researchers from the Northwestern University School of Medicine reported in their recent paper entitled "Altered Retinoid…

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